Search Results - "Dingermann, T"

The MLL recombinome of acute leukemias in 2013 by Meyer, C, Hofmann, J, Burmeister, T, Gröger, D, Park, T S, Emerenciano, M, Pombo de Oliveira, M, Renneville, A, Villarese, P, Macintyre, E, Cavé, H, Clappier, E, Mass-Malo, K, Zuna, J, Trka, J, De Braekeleer, E, De Braekeleer, M, Oh, S H, Tsaur, G, Fechina, L, van der Velden, V H J, van Dongen, J J M, Delabesse, E, Binato, R, Silva, M L M, Kustanovich, A, Aleinikova, O, Harris, M H, Lund-Aho, T, Juvonen, V, Heidenreich, O, Vormoor, J, Choi, W W L, Jarosova, M, Kolenova, A, Bueno, C, Menendez, P, Wehner, S, Eckert, C, Talmant, P, Tondeur, S, Lippert, E, Launay, E, Henry, C, Ballerini, P, Lapillone, H, Callanan, M B, Cayuela, J M, Herbaux, C, Cazzaniga, G, Kakadiya, P M, Bohlander, S, Ahlmann, M, Choi, J R, Gameiro, P, Lee, D S, Krauter, J, Cornillet-Lefebvre, P, Te Kronnie, G, Schäfer, B W, Kubetzko, S, Alonso, C N, zur Stadt, U, Sutton, R, Venn, N C, Izraeli, S, Trakhtenbrot, L, Madsen, H O, Archer, P, Hancock, J, Cerveira, N, Teixeira, M R, Lo Nigro, L, Möricke, A, Stanulla, M, Schrappe, M, Sedék, L, Szczepański, T, Zwaan, C M, Coenen, E A, van den Heuvel-Eibrink, M M, Strehl, S, Dworzak, M, Panzer-Grümayer, R, Dingermann, T, Klingebiel, T, Marschalek, R

“…Chromosomal rearrangements of the human MLL (mixed lineage leukemia) gene are associated with high-risk infant, pediatric, adult and therapy-induced acute…”
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Secondary mutations in t(4;11) leukemia patients by Prelle, C, Bursen, A, Dingermann, T, Marschalek, R

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Metamizole: Something to think about by Dingermann, T

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PEGylation--a well-proven strategy for the improvement of recombinant drugs by Zündorf, I, Dingermann, T

“…Protein and peptide drugs hold great promise as therapeutic agents. But there are shortcomings: Many recombinant proteins are quickly degraded by proteolytic…”
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The leukemogenic AF4-MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures by Benedikt, A, Baltruschat, S, Scholz, B, Bursen, A, Arrey, T N, Meyer, B, Varagnolo, L, Müller, A M, Karas, M, Dingermann, T, Marschalek, R

“…Expression of the AF4–MLL fusion protein in murine hematopoietic progenitor/stem cells results in the development of proB acute lymphoblastic leukemia. In this…”
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The MLL recombinome of acute leukemias by MEYER, C, SCHNEIDER, B, PIETERS, R, ENNAS, M.-G, ANGELUCCI, E, KOEHL, U, GREIL, J, GRIESINGER, F, ZUR STADT, U, ECKERT, C, SZCZEPANSKI, T, NIGGLI, F. K, JAKOB, S, SCHÄFER, B. W, KEMPSKI, H, BRADY, H. J. M, ZUNA, J, TRKA, J, NIGRO, L. L, BIONDI, A, DELABESSE, E, MACINTYRE, E, STANULLA, M, STREHL, S, SCHRAPPE, M, HAAS, O. A, BURMEISTER, T, DINGERMANN, T, KLINGEBIEL, T, MARSCHALEK, R, ATTARBASCHI, A, SCHNITTGER, S, SCHOCH, C, JANSEN, M. W. J. C, VAN DONGEN, J. J. M, DEN BOER, M. L

“…Chromosomal rearrangements of the human MLL gene are a hallmark for aggressive (high-risk) pediatric, adult and therapy-associated acute leukemias. These…”
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The heterodimerization domains of MLL-FYRN and FYRC-are potential target structures in t(4;11) leukemia by Pless, B, Oehm, C, Knauer, S, Stauber, R H, Dingermann, T, Marschalek, R

“…The chromosomal translocation t(4;11)(q21;q23) is a frequent genetic aberration of the mixed lineage leukemia ( MLL) gene, predominantly associated with…”
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Combined effects of the two reciprocal t(4;11) fusion proteins MLL AF4 and AF4 MLL confer resistance to apoptosis, cell cycling capacity and growth transformation by GAUSSMANN, A, WENGER, T, EBERLE, I, BURSEN, A, BRACHARZ, S, HERR, I, DINGERMANN, T, MARSCHALEK, R

“…The reciprocal chromosomal translocation t(4;11) is correlated with infant, childhood, adult and therapy-related high-risk acute leukemia. Here, we…”
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Transcription linked to recombination : a gene-internal promoter coincides with the recombination hot spot II of the human MLL gene by SCHARF, S, ZECH, J, BURSEN, A, SCHRAETS, D, OLIVER, P. L, KLIEM, S, PFITZNER, E, GILLERT, E, DINGERMANN, T, MARSCHALEK, R

“…The MLL gene is frequently involved in chromosomal translocations associated with high-risk acute leukaemia. Infant and therapy-related acute leukaemia…”
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Spliced MLL fusions: a novel mechanism to generate functional chimeric MLL-MLLT1 transcripts in t(11;19)(q23;p13.3) leukemia by Meyer, C, Burmeister, T, Strehl, S, Schneider, B, Hubert, D, Zach, O, Haas, O, Klingebiel, T, Dingermann, T, Marschalek, R

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Inv(11)(q21q23) fuses MLL to the Notch co-activator mastermind-like 2 in secondary T-cell acute lymphoblastic leukemia by Metzler, M, Staege, M S, Harder, L, Mendelova, D, Zuna, J, Fronkova, E, Meyer, C, Flohr, T, Bednarova, D, Harbott, J, Langer, T, Gesk, S, Trka, J, Siebert, R, Dingermann, T, Marschalek, R, Niemeyer, C, Rascher, W

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Renal accumulation and clearance of advanced glycation end-products in type 2 diabetic nephropathy : effect of angiotensin-converting enzyme and vasopeptidase inhibition by WIHLER, C, SCHÄFER, S, HUBER, J, SCHMID, K, DEEMER, E. K, MÜNCH, G, BLEICH, M, BUSCH, A. E, DINGERMANN, T, SOMOZA, V, BAYNES, J. W

“…Renal accumulation of AGEs may contribute to the progression of diabetic nephropathy. We evaluated the effect of ramipril (a pure ACE inhibitor) and AVE7688 (a…”
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An alternative to animal testing in the quality control of erythropoietin by Zimmermann, H, Gerhard, D, Hothorn, L A, Dingermann, T

“…A physico-chemical method has been developed as an alternative to the current bioassay in normocythaemic mice for estimating the biological activity of…”
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Dictyostelium mobile elements: strategies to amplify in a compact genome by Winckler, T, Dingermann, T, Glöckner, G

“…Dictyostelium discoideum is a eukaryotic microorganism that is attractive for the study of fundamental biological phenomena such as cell-cell communication,…”
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The AMNOG and its consequences by Dingermann, T

“…On 11 November 2010, the German Bundestag approved the law on the Reorganization of the Pharmaceutical Market (AMNOG). This act went into force on 01 January…”
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Monoclonal antibodies against an arabinogalactan-protein from pressed juice of Echinacea purpurea by Classen, B, Csávás, M, Borbás, A, Dingermann, T, Zündorf, I

“…Pressed juices of the aerial parts of Echinacea purpurea are used as non-specific immunostimulants, and arabinogalactan-proteins (AGPs) have been shown to be…”
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Inv(11)(q21q23) fuses MLL to the notch co-activator mastermind-like 2 in secondary T-cell acute lymphoblastic leukemia by Metzler, M, Staege, M S, Harder, L, Mendelova, D, Zuna, J, Fronkova, E, Meyer, C, Flohr, T, Bednarova, D, Harbott, J, Langer, T, Gesk, S, Trka, J, Siebert, R, Dingermann, T, Marschalek, R, Niemeyer, C, Rascher, W

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Template jumping by a LINE reverse transcriptase has created a SINE-like 5S rRNA retropseudogene in Dictyostelium by Szafranski, K, Dingermann, T, Glöckner, G, Winckler, T

“…Short interspersed nuclear elements (SINEs) are non-autonomous retroelements that mimic the 3' ends of so-called long interspersed nuclear elements (LINEs) to…”
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Enhanced in vitro oligonucleotide and plasmid DNA transport by VP1 virus-like particles by HENKE, S, ROHMANN, A, BERTLING, W. M, DINGERMANN, Th, ZIMMER, A

“…We developed a prokaryotic expression system to express the major capsid protein of Polyomavirus, VP1. Furthermore, we investigated the transport of single…”
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Metamizol: Something to think about by Dingermann, T.

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