Search Results - "Ding, YiLi"

Randomly Methylated β -Cyclodextrin Inclusion Complex with Ketoconazole: Preparation, Characterization, and Improvement of Pharmacological Profiles by Ding, Yili, Xu, Shufeng, Ding, Charles, Zhang, Zhiyuan, Xu, Zhe

“…As a powerful imidazole antifungal drug, ketoconazole's low solubility (0.017 mg/mL), together with its odor and irritation, limited its clinical applications…”
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The Use of Cyclodextrin Inclusion Complexes to Increase the Solubility and Pharmacokinetic Profile of Albendazole by Ding, Yili, Zhang, Zhiyuan, Ding, Charles, Xu, Shufeng, Xu, Zhe

“…Albendazole is the preferred deworming drug and has strong insecticidal effects on human and animal helminth parasites, showing remarkable activity against…”
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Solubility and Pharmacokinetic Profile Improvement of Griseofulvin through Supercritical Carbon Dioxide-Assisted Complexation with HP-γ-Cyclodextrin by Ding, Yili, Cui, Wutong, Zhang, Zhiyuan, Ma, Yanzhi, Ding, Charles, Lin, Yikai, Xu, Zhe

“…Since griseofulvin was marketed as a non-polyene antifungal antibiotic drug in 1958, its poor water solubility has been an issue for its wide applications, and…”
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Preparation and evaluation of fenbendazole methyl-β-cyclodextrin inclusion complexes by Ding, Yili, Zhang, Zhiyuan, Ding, Charles, Xu, Shufeng, Xu, Zhe

“…As an orally effective benzimidazole anthelmintic agent, fenbendazole was not only widely used in agriculture and animal husbandry to prevent and treat…”
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Improvement of solubility and pharmacokinetic profile of hepatoprotector icariin through complexation with HP- γ -cyclodextrin by Ding, Yili, Yu, Bo, Zhou, Shuzhen, Ding, Charles, Zhang, Zhiyuan, Xu, Shufeng, Xu, Zhe

“…Icariin as a hepatoprotector from can expand the cardiovascular and cerebral blood vessels, promote hematopoietic functions, enhance the immune system and show…”
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Formation of inclusion complex of enrofloxacin with 2-hydroxypropyl-β-cyclodextrin by Ding, Yili, Pang, Yuchang, Vara Prasad, Chamakura V. N. S., Wang, Bingyun

“…Enrofloxacin, a third-generation fluoroquinolone, is a broad-spectrum antimicrobial drug against a lot of veterinary bacterial diseases. However, bactericidal…”
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Glycosylation on Unprotected or Partially Protected Acceptors by Ding, Yili, Vara Prasad, Chamakura V. N. S., Wang, Bingyun

“…Over the last 30 years, there have been several methods developed for the synthesis of oligosaccharides, such as combinatorial synthesis, programmable one‐pot…”
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Preparation of inclusion complex of praziquantel with 2-hydroxypropyl-β-cyclodextrin and pharmacokinetic property improvement by Ding, Yili, Cui, Wutong, Pang, Yuchang, Vara Prasad, Chamakura V.N.S., Wang, Bingyun

“…An inclusion complex of praziquantel with 2-hydroxypropyl-β-cyclodextrin was designed and prepared by an optimized method and the inclusion complex was…”
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An ex vivo abomasal ovine model to study the immediate immune response in the context of Haemonchus contortus larval-stage by El-Ashram, Saeed, Li, Cuiping, Abouhajer, Fathi, Mehmood, Rashid, Al Nasr, Ibrahim, Zhang, Yinghui, Lu, Tang, Yili, Ding, Suo, Xun, Haoji, Zhang, Li, Zhili, Huang, Shujian

“…•Histological and transcriptional analyses of ovine abomasal explants.•A total of 233 were markedly up-regulated genes in response to L4-inoculation.•The…”
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Design and Synthesis of Lactose, Galactose and Cholic Acid Related Dual Conjugated Chitosan Derivatives as Potential Anti Liver Cancer Drug Carriers by Ding, Yili, Cui, Wutong, Vara Prasad, Chamakura V. N. S., Wang, Bingyun

“…Cholic acid and galactose or lactose dual conjugated chitosan derivatives were designed and synthesized as potential anti liver cancer drug carriers, their…”
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Synthesis of Gemcitabine Analogues as Potential Anti-tumor Agents by Ding, Yili

“…Gemcitabine analogue was designed to keep the anti-tumor activities but not to be the substrate of deoxycytidine deaminase. By coupling the…”
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Advances in Chemical Synthesis of Fondaparinux by Ding, Yili, Wang, Bingyun, Vara Prasad, Chamakura V. N. S.

“…Fondaparinux (trade name Arixtra) is a safe and efficacious anticoagulant, and it is chemically related to low-molecular-weight heparins such as enoxaparin…”
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Differential Biosynthesis of Polysialic Acid on Neural Cell Adhesion Molecule (NCAM) and Oligosaccharide Acceptors by Three Distinct α2,8-Sialyltransferases, ST8Sia IV (PST), ST8Sia II (STX), and ST8Sia III by Angata, Kiyohiko, Suzuki, Misa, McAuliffe, Joseph, Ding, Yili, Hindsgaul, Ole, Fukuda, Minoru

“…Polysialylated neural cell adhesion molecule (NCAM) is thought to play a critical role in neural development. Polysialylation of NCAM was shown to be achieved…”
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Synthesis of thiazolone-based sulfonamides as inhibitors of HCV NS5B polymerase by Ding, Yili, Smith, Kenneth L., Varaprasad, Chamakura V.N.S., Chang, Eugene, Alexander, John, Yao, Nanhua

“…Several thiazolone-based sulfonamides were prepared, utilizing various hetero-aryl sulfonyl chlorides and different aldehydes, as inhibitors of NS5B…”
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Design, synthesis, and evaluation of novel 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as potent and selective CXCR2 chemokine receptor antagonists by Liu, Shilan, Liu, Yinhui, Wang, Hongmei, Ding, YiLi, Wu, Hao, Dong, Jingchao, Wong, Angela, Chen, Shu-Hui, Li, Ge, Chan, Manuel, Sawyer, Nicole, Gervais, Francois G., Henault, Martin, Kargman, Stacia, Bedard, Leanne L., Han, Yongxin, Friesen, Rick, Lobell, Robert B., Stout, David M.

“…A novel series of 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as potent and selective CXCR2 chemokine receptor antagonists were identified. We describe…”
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Parallel synthesis of pteridine derivatives as potent inhibitors for hepatitis C virus NS5B RNA-dependent RNA polymerase by Ding, Yili, Girardet, Jean-Luc, Smith, Kenneth L., Larson, Gary, Prigaro, Brett, Lai, Vicky C.H., Zhong, Weidong, Wu, Jim Z.

“…[Display omitted] From compound library screening using an HCV NS5B RNA-dependent RNA polymerase enzymatic assay, we identified a pteridine hit compound with…”
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Synthesis of 9-(2-β- C-methyl-β- d-ribofuranosyl)-6-substituted purine derivatives as inhibitors of HCV RNA replication by Ding, Yili, Girardet, Jean-Luc, Hong, Zhi, Lai, Vicky C.H., An, Haoyun, Koh, Yung-hyo, Shaw, Stephanie Z., Zhong, Weidong

“…[Display omitted] A series of 9-(2′-β- C-methyl-β- d-ribofuranosyl)-6-substituted purine derivatives were synthesized as potential inhibitors of HCV RNA…”
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Synthesis of 2′-β- C-methyl toyocamycin and sangivamycin analogues as potential HCV inhibitors by Ding, Yili, An, Haoyun, Hong, Zhi, Girardet, Jean-Luc

“…[Display omitted] Coupling reaction of 2-β- C-methyl-1,2,3,4-tetra- O-benzoyl- d-ribofuranose with 4-amino-6-bromo-5-cyanopyrrolo[2,3- d]pyrimidine, followed…”
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Preparation of trimethoprim/methyl β-cyclodextrin complexes, in vitro and in vivo pharmacokinetic study, and evaluation of antibacterial activity in combination with the complex of sulfamethoxazole/methyl β-cyclodextrin by Ding, Yili, Ma, Yanzhi, Ding, Charles, Nie, Jiehua, Xu, Zhe

“…•The inclusion complexes of trimethoprim/cyclodextrin were prepared and confirmed by NMR, DSC and FTIR.•The solubility of trimethoprim was increased 1500-2600…”
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Randomly Methylated Iβ/I-Cyclodextrin Inclusion Complex with Ketoconazole: Preparation, Characterization, and Improvement of Pharmacological Profiles by Ding, Yili, Xu, Shufeng, Ding, Charles, Zhang, Zhiyuan, Xu, Zhe

“…As a powerful imidazole antifungal drug, ketoconazole’s low solubility (0.017 mg/mL), together with its odor and irritation, limited its clinical applications…”
Get full text