Search Results - "Ding, Isabelle"

Contribution of the Immune Response to Phage Therapy by Krut, Oleg, Bekeredjian-Ding, Isabelle

“…Therapeutic phages are being employed for vaccination and treatment of cancer and bacterial infections. Their natural immunogenicity triggers intertwined…”
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Prevalence and antibiotic susceptibility trends of periodontal pathogens in the subgingival microbiota of German periodontitis patients: A retrospective surveillance study by Jepsen, Karin, Falk, Wolfgang, Brune, Friederike, Fimmers, Rolf, Jepsen, Søren, Bekeredjian‐Ding, Isabelle

“…Objective This retrospective surveillance study aimed to follow periodontitis‐associated bacterial profiles and to identify time‐dependent changes in…”
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Toll-like receptors - sentries in the B-cell response by Bekeredjian-Ding, Isabelle, Jego, Gaetan

“…Toll-like receptors (TLR) play a central role in the initiation of the innate immune response to pathogens. Upon recognition of molecular motifs specific for…”
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Plasmacytoid Dendritic Cells Control TLR7 Sensitivity of Naive B Cells via Type I IFN by Bekeredjian-Ding, Isabelle Beatrice, Wagner, Moritz, Hornung, Veit, Giese, Thomas, Schnurr, Max, Endres, Stefan, Hartmann, Gunther

“…Detailed information of human B cell activation via TLR may lead to a better understanding of B cell involvement in autoimmunity and malignancy. In this study…”
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TNFR2 expression is a hallmark of human memory B cells with suppressive function by Ticha, Olga, Slanina, Peter, Moos, Lukas, Stichova, Julie, Vlkova, Marcela, Bekeredjian‐Ding, Isabelle

“…Tumor Necrosis Factor Receptor 2 (TNFR2) expression is increasingly being linked to tolerogenic immune reactions and cells with suppressor function including a…”
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DGfI Study Group Vaccines ‐ Annual Meeting 2022 by Wöhrle, Franziska, Kerscher, Bernhard, Cicin‐Sain, Luka, Bekeredjian‐Ding, Isabelle

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Challenges for Clinical Development of Vaccines for Prevention of Hospital-Acquired Bacterial Infections by Bekeredjian-Ding, Isabelle

“…Increasing antibiotic resistance in bacteria causing endogenous infections has entailed a need for innovative approaches to therapy and prophylaxis of these…”
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Characterization of transfusion-relevant bacteria reference strains in a lyophilized format by Prax, Marcel, McDonald, Carl P, Bekeredjian-Ding, Isabelle, Cloutier, Marc, Gravemann, Ute, Grothaus, Anna, Krut, Oleg, Mpumlwana, Xoliswa, O'Flaherty, Niamh, Satake, Masahiro, Stafford, Bianca, Suessner, Susanne, Vollmer, Tanja, Ramirez-Arcos, Sandra

“…Blood safety measures used by blood establishments to increase blood component safety can be validated using Transfusion-Relevant Bacterial Reference Strains…”
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Whole-exome sequencing links caspase recruitment domain 11 ( CARD11 ) inactivation to severe combined immunodeficiency by Greil, Johann, MD, Rausch, Tobias, PhD, Giese, Thomas, MD, Bandapalli, Obul R., PhD, Daniel, Volker, MD, Bekeredjian-Ding, Isabelle, MD, Stütz, Adrian M., PhD, Drees, Christoph, MD, Roth, Susanne, MD, Ruland, Jürgen, MD, Korbel, Jan O., PhD, Kulozik, Andreas E., MD, PhD

“…Background Primary immunodeficiencies represent model diseases for the mechanistic understanding of the human innate and adaptive immune response. They are…”
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Impact of hepatitis E virus testing on the safety of blood components in Germany – results of a simulation study by Kamp, Christel, Blümel, Johannes, Baylis, Sally A., Bekeredjian‐Ding, Isabelle, Chudy, Michael, Heiden, Margarethe, Henseler, Olaf, Keller‐Stanislawski, Brigitte, de Vos, Anneke S., Funk, Markus B.

“…Hepatitis E virus (HEV) infections may be acquired through transfusion of blood components. As transfusion‐transmitted infections mostly affect vulnerable…”
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Optimizing the dynamics of protein expression by Trösemeier, Jan-Hendrik, Rudorf, Sophia, Loessner, Holger, Hofner, Benjamin, Reuter, Andreas, Schulenborg, Thomas, Koch, Ina, Bekeredjian-Ding, Isabelle, Lipowsky, Reinhard, Kamp, Christel

“…Heterologously expressed genes require adaptation to the host organism to ensure adequate levels of protein synthesis, which is typically approached by…”
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Individual combinations of danger signals synergistically increase FVIII product immunogenicity by Miller, Lilija, Klemm, Jessica, Schmidt, Carolin, Hanschmann, Kay‐Martin, Bekeredjian‐Ding, Isabelle, Waibler, Zoe

“…Introduction The most severe side effect in haemophilia A treatment is the development of antifactor VIII antibodies, also called inhibitors. Why inhibitors…”
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Establishment of transfusion‐relevant bacteria reference strains for red blood cells by Prax, Marcel, Spindler‐Raffel, Eva, McDonald, Carl Peter, Bearne, Jennifer, Satake, Masahiro, Kozakai, Moe, Rojo, Julieta, Hanschmann, Kay‐Martin O., Lambrecht, Bernd, Grundmann, Udo, O’Flaherty, Niamh, Klimek, Agata, Bekeredjian‐Ding, Isabelle, Gathof, Birgit S., Störmer, Melanie, Süßner, Susanne, Renke, Claudia, Lee, Cheuk‐kwong, Knabbe, Cornelius, Vollmer, Tanja, Keil, Shawn D., Shipps, Marley E., Wagner, Stephen J., Jentsch, Ute, Mpumlwana, Xoliswa, Cloutier, Marc, Bringmann, Peter, Lu, Thea, Ramirez‐Arcos, Sandra, Kou, Yuntong, Krut, Oleg

“…Background and objectives Red blood cell concentrates (RBCC) are susceptible to bacterial contamination despite cold storage. A reliable evaluation of…”
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Publisher Correction: Optimizing the dynamics of protein expression by Trösemeier, Jan-Hendrik, Rudorf, Sophia, Loessner, Holger, Hofner, Benjamin, Reuter, Andreas, Schulenborg, Thomas, Koch, Ina, Bekeredjian-Ding, Isabelle, Lipowsky, Reinhard, Kamp, Christel

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Assessment of the involvement of the macrophage migration inhibitory factor–glucocorticoid regulatory dyad in the expression of matrix metalloproteinase‐2 during periodontitis by Hirschfeld, Josefine, Howait, Mohammed, Movila, Alexandru, Parčina, Marijo, Bekeredjian‐Ding, Isabelle, Deschner, James, Jepsen, Søren, Kawai, Toshihisa

“…Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine and counter‐regulator of endogenous glucocorticoids (GCs). It is implicated in acute…”
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Tumour‐derived prostaglandin E 2 and transforming growth factor‐β synergize to inhibit plasmacytoid dendritic cell‐derived interferon‐α by Bekeredjian‐Ding, Isabelle, Schäfer, Meike, Hartmann, Evelyn, Pries, Ralph, Parcina, Marijo, Schneider, Philip, Giese, Thomas, Endres, Stefan, Wollenberg, Barbara, Hartmann, Gunther

“…Summary In previous studies we reported that plasmacytoid dendritic cells (PDC) infiltrating head and neck cancer tissue are functionally impaired, but the…”
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A cell-based in vitro assay for testing of immunological integrity of Tetanus toxoid vaccine antigen by Ticha, Olga, Klemm, Dido, Moos, Lukas, Bekeredjian-Ding, Isabelle

“…Vaccines containing inactivated toxins confer protection by eliciting a neutralizing antibody response against bacterial toxins such as tetanus and diphtheria…”
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Ca2+‐related signaling events influence TLR9‐induced IL‐10 secretion in human B cells by Ziegler, Saskia, Gartner, Katrin, Scheuermann, Uwe, Zoeller, Tanja, Hantzschmann, Julia, Over, Benjamin, Foermer, Sandra, Heeg, Klaus, Bekeredjian‐Ding, Isabelle

“…Suppressory B‐cell function controls immune responses and is mainly dependent on IL‐10 secretion. Pharmacological manipulation of B‐cell‐specific IL‐10…”
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Prioritizing of bacterial infections transmitted through substances of human origin in Europe by Domanović, Dragoslav, Cassini, Alessandro, Bekeredjian‐Ding, Isabelle, Bokhorst, Arlinke, Bouwknegt, Martijn, Facco, Giuseppina, Galea, George, Grossi, Paolo, Jashari, Ramadan, Jungbauer, Christoph, Marcelis, Jan, Raluca‐Siska, Ioana, Andersson‐Vonrosen, Inger, Suk, Jonathan E.

“…BACKGROUND Bacteria are the pathogens most frequently transmitted through substances of human origin (SoHO). The European Centre for Disease Prevention and…”
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Expression of Tumor Necrosis Factor Receptor 2 Characterizes TLR9-Driven Formation of Interleukin-10-Producing B Cells by Ticha, Olga, Moos, Lukas, Wajant, Harald, Bekeredjian-Ding, Isabelle

“…B cell-derived interleukin-10 (IL-10) production has been described as a hallmark for regulatory function in B lymphocytes. However, there is an ongoing debate…”
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