Search Results - "Ding, Hanying"
-
1
MicroRNA-30a Sensitizes Tumor Cells to cis-Platinum via Suppressing Beclin 1-mediated Autophagy
Published in The Journal of biological chemistry (03-02-2012)“…Autophagy is activated in cancer cells during chemotherapy and often contributes to tumor chemotherapy resistance. In this study, we characterized the role of…”
Get full text
Journal Article -
2
Fasting induces a subcutaneous-to-visceral fat switch mediated by microRNA-149-3p and suppression of PRDM16
Published in Nature communications (31-05-2016)“…Visceral adiposity is strongly associated with metabolic disease risk, whereas subcutaneous adiposity is comparatively benign. However, their relative…”
Get full text
Journal Article -
3
MicroRNA-10a/b inhibit TGF-β/Smad-induced renal fibrosis by targeting TGF-β receptor 1 in diabetic kidney disease
Published in Molecular therapy. Nucleic acids (14-06-2022)“…TGF-β/Smad signaling plays a vital role in the development of fibrosis in diabetic kidney disease (DKD). However, remedies targeting key elements in TGF-β/Smad…”
Get full text
Journal Article -
4
Kidney-secreted erythropoietin lowers lipidemia via activating JAK2-STAT5 signaling in adipose tissue
Published in EBioMedicine (01-12-2019)“…Dyslipidemia is commonly observed in various kidney diseases, renal specific secreted erythropoietin (EPO) may participate in this process. However, how this…”
Get full text
Journal Article -
5
Norathyriol reverses obesity- and high-fat-diet-induced insulin resistance in mice through inhibition of PTP1B
Published in Diabetologia (01-10-2014)“…Aim/hypothesis Protein tyrosine phosphatase 1B (PTP1B) negatively regulates insulin signalling. PTP1B deficiency improves obesity-induced insulin resistance…”
Get full text
Journal Article -
6
Environmental pollution and kidney diseases
Published in Nature reviews. Nephrology (01-05-2018)“…Key Points Up to 22% of the global burden of disease and 23% of deaths are attributable to environmental pollution; the general public is inevitably exposed to…”
Get full text
Journal Article -
7
MicroRNA-10 negatively regulates inflammation in diabetic kidney via targeting activation of the NLRP3 inflammasome
Published in Molecular therapy (07-07-2021)“…NLRP3 (NOD-, LRR-, and pyrin domain-containing protein 3) inflammasome activation has emerged as a central mediator of kidney inflammation in diabetic kidney…”
Get full text
Journal Article -
8
MicroRNA-19b/221/222 induces endothelial cell dysfunction via suppression of PGC-1α in the progression of atherosclerosis
Published in Atherosclerosis (01-08-2015)“…Abstract Background Peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) is a master regulator of cellular energy metabolism that is associated…”
Get full text
Journal Article -
9
Tumor-suppressive miR-218-5p inhibits cancer cell proliferation and migration via EGFR in non-small cell lung cancer
Published in Oncotarget (10-05-2016)“…Lung cancer remains the leading cause of cancer-related death worldwide, and non-small cell lung cancer (NSCLC) accounts for approximately 80% of lung cancer…”
Get full text
Journal Article -
10
Co-targeting of EGFR by co-expressed miRNA-193a-3p/−5p in lung cancer
Published in ExRNA (06-12-2019)Get full text
Journal Article