Search Results - "Dinesh Deelchand"

Simultaneous frequency and phase corrections of single‐shot MRS data using cross‐correlation by Deelchand, Dinesh K.

“…Purpose The objective of this study was to propose a novel preprocessing approach to simultaneously correct for the frequency and phase drifts in MRS data…”
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Cystathionine as a marker for 1p/19q codeleted gliomas by in vivo magnetic resonance spectroscopy by Branzoli, Francesca, Pontoizeau, Clément, Tchara, Lucien, Di Stefano, Anna Luisa, Kamoun, Aurélie, Deelchand, Dinesh K, Valabrègue, Romain, Lehéricy, Stéphane, Sanson, Marc, Ottolenghi, Chris, Marjańska, Małgorzata

“…Abstract Background Codeletion of chromosome arms 1p and 19q (1p/19q codeletion) highly benefits diagnosis and prognosis in gliomas. In this study, we…”
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Quantification of GABA concentration measured noninvasively in the human posterior cingulate cortex with 7 T ultra-short-TE MR spectroscopy by Genovese, Guglielmo, Deelchand, Dinesh K, Terpstra, Melissa, Marjańska, Małgorzata

“…The increased spectral dispersion achieved at ultra-high field permits quantification of γ-aminobutyric acid (GABA) concentrations at ultra-short-TE without…”
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Improved localization, spectral quality, and repeatability with advanced MRS methodology in the clinical setting by Deelchand, Dinesh K., Kantarci, Kejal, Öz, Gülin

“…Purpose To investigate the utility of an advanced magnetic resonance spectroscopy (MRS) protocol in the clinical setting, and to compare the localization…”
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Neurochemical and BOLD Responses during Neuronal Activation Measured in the Human Visual Cortex at 7 Tesla by Bednařík, Petr, Tkáč, Ivan, Giove, Federico, DiNuzzo, Mauro, Deelchand, Dinesh K, Emir, Uzay E, Eberly, Lynn E, Mangia, Silvia

“…Several laboratories have consistently reported small concentration changes in lactate, glutamate, aspartate, and glucose in the human cortex during prolonged…”
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Test-retest reproducibility of neurochemical profiles with short-echo, single-voxel MR spectroscopy at 3T and 7T by Terpstra, Melissa, Cheong, Ian, Lyu, Tianmeng, Deelchand, Dinesh K., Emir, Uzay E., Bednařík, Petr, Eberly, Lynn E., Öz, Gülin

“…Purpose To determine the test‐retest reproducibility of neurochemical concentrations obtained with a highly optimized, short‐echo, single‐voxel proton MR…”
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Results and interpretation of a fitting challenge for MR spectroscopy set up by the MRS study group of ISMRM by Marjańska, Małgorzata, Deelchand, Dinesh K., Kreis, Roland, Alger, Jeffry R., Bolan, Patrick J., Borbath, Tamas, Boumezbeur, Fawzi, Fernandes, Carolina C., Coello, Eduardo, Nagraja, Bharath Halandur, Považan, Michal, Ratiney, Hélène, Sima, Diana, Starčuková, Jana, Soher, Brian J., Wilson, Martin, Asten, Jack J.A.

“…Purpose Fitting of MRS data plays an important role in the quantification of metabolite concentrations. Many different spectral fitting packages are used by…”
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In vivo 1H MR spectroscopy with J‐refocusing by Deelchand, Dinesh K., Walls, Jamie D., Marjańska, Małgorzata

“…Purpose The goal of this study was to propose a novel localized proton MR spectroscopy (MRS) sequence that reduces signal loss due to J‐modulation in the rat…”
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In vivo 1 H MR spectroscopy with J-refocusing by Deelchand, Dinesh K, Walls, Jamie D, Marjańska, Małgorzata

“…The goal of this study was to propose a novel localized proton MR spectroscopy (MRS) sequence that reduces signal loss due to J-modulation in the rat brain in…”
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B 0 -insensitive image navigators for prospective motion-corrected MRS with localized second-order shimming by Adanyeguh, Isaac M, Park, Young Woo, Henry, Pierre-Gilles, Deelchand, Dinesh K

“…Localized shimming in single-voxel MRS often results in large B inhomogeneity outside the volume-of-interest. This causes unacceptable degradation in motion…”
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Apparent diffusion coefficients of the five major metabolites measured in the human brain in vivo at 3T by Deelchand, Dinesh K., Auerbach, Edward J., Marjańska, Małgorzata

“…Purpose To measure the apparent diffusion coefficients (ADC) of five main metabolites in the human brain at 3T with PRESS and STEAM, avoiding measurement…”
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Neurochemical Differences between 1p/19q Codeleted and Noncodeleted IDH-mutant Gliomas by in Vivo MR Spectroscopy by Branzoli, Francesca, Liserre, Roberto, Deelchand, Dinesh K, Poliani, Pietro Luigi, Bielle, Franck, Nichelli, Lucia, Sanson, Marc, Lehéricy, Stéphane, Marjańska, Małgorzata

“…Background Noninvasive identification of glioma subtypes is important for optimizing treatment strategies. Purpose To compare the in vivo neurochemical…”
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Neurochemical abnormalities in premanifest and early spinocerebellar ataxias by Joers, James M., Deelchand, Dinesh K., Lyu, Tianmeng, Emir, Uzay E., Hutter, Diane, Gomez, Christopher M., Bushara, Khalaf O., Eberly, Lynn E., Öz, Gülin

“…Objective To investigate whether early neurochemical abnormalities are detectable by high‐field magnetic resonance spectroscopy (MRS) in individuals with…”
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In vivo H MRS detection of cystathionine in human brain tumors by Branzoli, Francesca, Deelchand, Dinesh, Sanson, Marc, Lehéricy, Stéphane, Marjańska, Małgorzata

“…Purpose: To report the technical aspects of noninvasive detection of cystathionine in human brain glioma with edited MRS, and to investigate possible further…”
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Highly specific determination of IDH status using edited in vivo magnetic resonance spectroscopy by Branzoli, Francesca, Di Stefano, Anna Luisa, Capelle, Laurent, Ottolenghi, Chris, Valabrègue, Romain, Deelchand, Dinesh K, Bielle, Franck, Villa, Chiara, Baussart, Bertrand, Lehéricy, Stéphane, Sanson, Marc, Marjanska, Malgorzata

“…Mutations in the isocitrate dehydrogenase (IDH) enzyme affect 40% of gliomas and represent a major diagnostic and prognostic marker. The goals of this study…”
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MEGA‐PRESS of GABA+: Influences of acquisition parameters by Deelchand, Dinesh K., Marjańska, Małgorzata, Henry, Pierre‐Gilles, Terpstra, Melissa

“…γ‐aminobutyric acid (GABA) was the first molecule that was edited with MEGA‐PRESS. GABA edited spectroscopy is challenged by limited selectivity of editing…”
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Prospective motion correction for cervical spinal cord MRS by Adanyeguh, Isaac M., Henry, Pierre‐Gilles, Deelchand, Dinesh K.

“…Purpose To develop prospective motion correction for single‐voxel MRS in the human cervical spinal cord. Methods A motion MR navigator was implemented using…”
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A natural history study to track brain and spinal cord changes in individuals with Friedreich's ataxia: TRACK-FA study protocol by Georgiou-Karistianis, Nellie, Corben, Louise A, Reetz, Kathrin, Adanyeguh, Isaac M, Corti, Manuela, Deelchand, Dinesh K, Delatycki, Martin B, Dogan, Imis, Evans, Rebecca, Farmer, Jennifer, França, Marcondes C, Gaetz, William, Harding, Ian H, Harris, Karen S, Hersch, Steven, Joules, Richard, Joers, James J, Krishnan, Michelle L, Lax, Michelle, Lock, Eric F, Lynch, David, Mareci, Thomas, Muthuhetti Gamage, Sahan, Pandolfo, Massimo, Papoutsi, Marina, Rezende, Thiago J R, Roberts, Timothy P L, Rosenberg, Jens T, Romanzetti, Sandro, Schulz, Jörg B, Schilling, Traci, Schwarz, Adam J, Subramony, Sub, Yao, Bert, Zicha, Stephen, Lenglet, Christophe, Henry, Pierre-Gilles

“…Drug development for neurodegenerative diseases such as Friedreich's ataxia (FRDA) is limited by a lack of validated, sensitive biomarkers of pharmacodynamic…”
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On the relationship between GABA+ and glutamate across the brain by Rideaux, Reuben, Ehrhardt, Shane E., Wards, Yohan, Filmer, Hannah L., Jin, Jin, Deelchand, Dinesh K., Marjańska, Małgorzata, Mattingley, Jason B., Dux, Paul E.

“…Equilibrium between excitation and inhibition (E/I balance) is key to healthy brain function. Conversely, disruption of normal E/I balance has been implicated…”
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The influence of cystathionine on neurochemical quantification in brain tumor in vivo MR spectroscopy by Branzoli, Francesca, Deelchand, Dinesh K., Liserre, Roberto, Poliani, Pietro Luigi, Nichelli, Lucia, Sanson, Marc, Lehéricy, Stéphane, Marjańska, Małgorzata

“…Purpose To evaluate the ability of the PRESS sequence (TE = 97 ms, optimized for 2‐hydroxyglutarate detection) to detect cystathionine in gliomas and the…”
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