Search Results - "Dinesh, S"
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Glycosylated Porphyrins, Phthalocyanines, and Other Porphyrinoids for Diagnostics and Therapeutics
Published in Chemical reviews (23-09-2015)“…An examination of the therapeutics and diagnostics use of porphyrinoids including phthalocyanines and glycosylated porphyrins is offered. Topics covered…”
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2
Coumarin hybrid derivatives as promising leads to treat tuberculosis: Recent developments and critical aspects of structural design to exhibit anti-tubercular activity
Published in Tuberculosis (Edinburgh, Scotland) (01-03-2021)“…Tuberculosis (TB) is a highly contagious airborne disease with nearly 25% of the world's population infected with it. Challenges such as multi drug resistant…”
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3
microRNA Regulation of Inflammatory Responses
Published in Annual review of immunology (01-01-2012)“…The mammalian inflammatory response is a rapid and complex physiological reaction to noxious stimuli including microbial pathogens. Although inflammation plays…”
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4
Fluorinated porphyrinoids as efficient platforms for new photonic materials, sensors, and therapeutics
Published in Organic & biomolecular chemistry (01-01-2016)“…Porphyrinoids are robust heterocyclic dyes studied extensively for their applications in medicine and as photonic materials because of their tunable…”
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5
Physiological and pathological roles for microRNAs in the immune system
Published in Nature reviews. Immunology (01-02-2010)“…Key Points MicroRNAs (miRNAs) are expressed by cells that constitute the immune system, and they function by repressing specific mRNA targets at the…”
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6
Antibody-based protection against HIV infection by vectored immunoprophylaxis
Published in Nature (London) (05-01-2012)“…A single injection of a viral vector that encodes antibodies able to neutralize most HIV strains protects humanized mice from HIV infection. Anti-HIV…”
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Antimicrobial and anti-inflammatory activities of short dodecapeptides derived from duck cathelicidin: Plausible mechanism of bactericidal action and endotoxin neutralization
Published in European journal of medicinal chemistry (15-10-2020)“…Antimicrobial peptides (AMPs) have gained increasing attention to combat antibiotic-resistant pathogens. dCATH (duck cathelicidin) is a 20-residue avian…”
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8
Cancer cell spheroids are a better screen for the photodynamic efficiency of glycosylated photosensitizers
Published in PloS one (17-05-2017)“…Photodynamic Therapy (PDT) relies on the use of non-toxic photosensitizers that are locally and selectively activated by light to induce cell death or…”
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A randomized synbiotic trial to prevent sepsis among infants in rural India
Published in Nature (London) (24-08-2017)“…Sepsis in early infancy results in one million annual deaths worldwide, most of them in developing countries. No efficient means of prevention is currently…”
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10
Inositol phosphatase SHIP1 is a primary target of miR-155
Published in Proceedings of the National Academy of Sciences - PNAS (28-04-2009)“…MicroRNA-155 (miR-155) has emerged as a critical regulator of immune cell development, function, and disease. However, the mechanistic basis for its impact on…”
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11
MicroRNAs: new regulators of immune cell development and function
Published in Nature immunology (01-08-2008)“…Decades of research went into understanding immune cell development and function without awareness that consideration of a key element, microRNA (miRNA), was…”
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Parameters of Porosity and Compressive Strength-Based Optimization on Reinforced Aluminium from the Recycled Waste Automobile Frames
Published in Advances in materials science and engineering (2021)“…Automobile industries were ready to recycle the waste old parts as well as the damaged parts of the old vehicles as much as possible. This study mainly focused…”
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13
Proinflammatory NFkB signalling promotes mitochondrial dysfunction in skeletal muscle in response to cellular fuel overloading
Published in Cellular and molecular life sciences : CMLS (01-12-2019)“…Sustained nutrient (fuel) excess, as occurs during obesity and diabetes, has been linked to increased inflammation, impaired mitochondrial homeostasis,…”
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14
Energy-Efficient Design of Hybrid MTJ/CMOS and MTJ/Nanoelectronics Circuits
Published in IEEE transactions on magnetics (01-07-2018)“…As CMOS technology scales down to the nanoscale, high leakage power consumption becomes one of the major concerns in the design of electronic circuits. To…”
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15
miRNA dysregulation in cancer: towards a mechanistic understanding
Published in Frontiers in genetics (18-03-2014)“…It is now well known that gene expression is intricately regulated inside each cell especially in mammals. There are multiple layers of gene regulation active…”
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miR-155 Promotes T Follicular Helper Cell Accumulation during Chronic, Low-Grade Inflammation
Published in Immunity (Cambridge, Mass.) (16-10-2014)“…Chronic inflammation is a contributing factor to most life-shortening human diseases. However, the molecular and cellular mechanisms that sustain chronic…”
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miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice
Published in The Journal of experimental medicine (06-06-2011)“…Excessive or inappropriate activation of the immune system can be deleterious to the organism, warranting multiple molecular mechanisms to control and properly…”
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Exploration of Non-Volatile MTJ/CMOS Circuits for DPA-Resistant Embedded Hardware
Published in IEEE transactions on magnetics (01-12-2019)“…Magnetic tunnel junction (MTJ/CMOS-based Logic-in-Memory (LiM) circuits have nearly zero leakage power dissipation, and they are very appropriate to design…”
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Vectored immunoprophylaxis protects humanized mice from mucosal HIV transmission
Published in Nature medicine (01-03-2014)“…Delivery of HIV-specific neutralizing antibodies by adeno-associated virus vectors—termed vectored immunoprophylaxis (VIP)—has been shown to protect mice or…”
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MicroRNA function in myeloid biology
Published in Blood (15-09-2011)“…The past 5 years have seen an explosion of knowledge about miRNAs and their roles in hematopoiesis, cancer, and other diseases. In myeloid development, there…”
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