Search Results - "Dinchhana, Lal"

Dual PI3Kδγ inhibition demonstrates potent anticancer effects in diffuse large B-cell lymphoma models: Discovery and preclinical characterization of LL-00084282 by Verma, Mahip K., Samant, Charudatt, Kale, Ramesh, Patra, Sukanya, Mahajan, Nilesh, Gholve, Milind K., Marisetti, Ajitkumar, Sunkara, Brahmam, Naik, Aditya, Shingare, Manisha, Reddy, Madhusudhan, Bokare, Anand M., Akarte, Atul, Koul, Sarita, Nigade, Prashant B., Patil, Vinod B., Modi, Dipak, Ahirrao, Prajakta, Pawar, Shashikant, Kuldharan, Sandip, Dinchhana, Lal, Mehta, Maneesh, Gundu, Jayasagar, Jana, Nirmal, Vidhate, Prashant, Mahangare, Sachin Jaysing, Shukla, Manojkumar R., Goel, Rajan N., Bhonde, Mandar, Kamboj, Rajender Kumar, Palle, Venkata P.

“…Phosphoinositide 3-kinase (PI3K) pathway mediates key signaling events downstream to B-cell receptor (BCR) for survival of mature B-cells, and overexpression…”
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Discovery of a Potent and Selective PI3Kδ Inhibitor ( S )-2,4-Diamino-6-((1-(7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenyl-4 H -quinolizin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile with Improved Pharmacokinetic Profile and Superior Efficacy in Hematological Cancer Models by Shukla, Manojkumar R, Patra, Sukanya, Verma, Mahip, Sadasivam, Gayathri, Jana, Nirmal, Mahangare, Sachin J, Vidhate, Prashant, Lagad, Dipak, Tarage, Anand, Cheemala, Murthy, Kulkarni, Chaitanya, Bhagwat, Shankar, Chaudhari, Vinod D, Sayyed, Majid, Pachpute, Vipul, Phadtare, Ramesh, Gole, Gopal, Phukan, Samiron, Sunkara, Brahmam, Samant, Charudatt, Shingare, Manisha, Naik, Aditya, Trivedi, Sneha, Marisetti, Ajit Kumar, Reddy, Madhusudhan, Gholve, Milind, Mahajan, Nilesh, Sabde, Sudeep, Patil, Vinod, Modi, Dipak, Mehta, Maneesh, Nigade, Prashant, Tamane, Kaustubh, Tota, Swati, Goyal, Hemant, Volam, Harish, Pawar, Shashikant, Ahirrao, Prajakta, Dinchhana, Lal, Mallurwar, Sadanand, Akarte, Atul, Bokare, Anand, Kanhere, Rupesh, Reddy, Neetinkumar, Koul, Sarita, Dandekar, Manoj, Singh, Minakshi, Bernstein, Peter R, Narasimham, Lakshmi, Bhonde, Mandar, Gundu, Jayasagar, Goel, Rajan, Kulkarni, Sanjeev, Sharma, Sharad, Kamboj, Rajender Kumar, Palle, Venkata P

“…PI3Kδ inhibitors have been approved for B-cell malignancies like CLL, small lymphocytic lymphoma, and so forth. However, currently available PI3Kδ inhibitors…”
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Discovery of a Potent and Selective PI3Kδ Inhibitor (S)‑2,4-Diamino-6-((1-(7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenyl‑4H‑quinolizin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile with Improved Pharmacokinetic Profile and Superior Efficacy in Hematological Cancer Models by Shukla, Manojkumar R, Patra, Sukanya, Verma, Mahip, Sadasivam, Gayathri, Jana, Nirmal, Mahangare, Sachin J, Vidhate, Prashant, Lagad, Dipak, Tarage, Anand, Cheemala, Murthy, Kulkarni, Chaitanya, Bhagwat, Shankar, Chaudhari, Vinod D, Sayyed, Majid, Pachpute, Vipul, Phadtare, Ramesh, Gole, Gopal, Phukan, Samiron, Sunkara, Brahmam, Samant, Charudatt, Shingare, Manisha, Naik, Aditya, Trivedi, Sneha, Marisetti, Ajit Kumar, Reddy, Madhusudhan, Gholve, Milind, Mahajan, Nilesh, Sabde, Sudeep, Patil, Vinod, Modi, Dipak, Mehta, Maneesh, Nigade, Prashant, Tamane, Kaustubh, Tota, Swati, Goyal, Hemant, Volam, Harish, Pawar, Shashikant, Ahirrao, Prajakta, Dinchhana, Lal, Mallurwar, Sadanand, Akarte, Atul, Bokare, Anand, Kanhere, Rupesh, Reddy, Neetinkumar, Koul, Sarita, Dandekar, Manoj, Singh, Minakshi, Bernstein, Peter R, Narasimham, Lakshmi, Bhonde, Mandar, Gundu, Jayasagar, Goel, Rajan, Kulkarni, Sanjeev, Sharma, Sharad, Kamboj, Rajender Kumar, Palle, Venkata P

“…PI3Kδ inhibitors have been approved for B-cell malignancies like CLL, small lymphocytic lymphoma, and so forth. However, currently available PI3Kδ inhibitors…”
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