Search Results - "Dinasarapu, Ashok R"
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Correction: Signatures of somatic mutations and gene expression from p16INK4A positive head and neck squamous cell carcinomas (HNSCC)
Published in PloS one (2024)“…[This corrects the article DOI: 10.1371/journal.pone.0238497.]…”
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2
Spiny projection neurons exhibit transcriptional signatures within subregions of the dorsal striatum
Published in Cell reports (Cambridge) (28-11-2023)“…The dorsal striatum is organized into functional territories defined by corticostriatal inputs onto both direct and indirect spiny projection neurons (SPNs),…”
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3
Anti-inflammatory effects of recreational marijuana in virally suppressed youth with HIV-1 are reversed by use of tobacco products in combination with marijuana
Published in Retrovirology (31-05-2022)“…Marijuana's putative anti-inflammatory properties may benefit HIV-associated comorbidities. How recreational marijuana use affects gene expression in…”
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Induced pluripotent stem cells from subjects with Lesch-Nyhan disease
Published in Scientific reports (19-04-2021)“…Lesch-Nyhan disease (LND) is an inherited disorder caused by pathogenic variants in the HPRT1 gene, which encodes the purine recycling enzyme…”
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Neuroinflammatory transcriptional programs induced in rhesus pre-frontal cortex white matter during acute SHIV infection
Published in Journal of neuroinflammation (06-10-2022)“…Immunosurveillance of the central nervous system (CNS) is vital to resolve infection and injury. However, immune activation within the CNS in the setting of…”
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6
Analysis of inflammatory and lipid metabolic networks across RAW264.7 and thioglycolate-elicited macrophages
Published in Journal of lipid research (01-09-2013)“…Studies of macrophage biology have been significantly advanced by the availability of cell lines such as RAW264.7 cells. However, it is unclear how these cell…”
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Signatures of somatic mutations and gene expression from p16INK4A positive head and neck squamous cell carcinomas (HNSCC)
Published in PloS one (2020)“…Human papilloma virus (HPV) causes a subset of head and neck squamous cell carcinomas (HNSCC) of the oropharynx. We combined targeted DNA- and genome-wide…”
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8
Uric Acid in Parkinson's Disease: What Is the Connection?
Published in Movement disorders (01-11-2022)“…Numerous studies have linked Parkinson's disease (PD) with low levels of uric acid (UA). Low UA has been associated with the risk of developing PD, and its…”
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Uric Acid in Parkinson′s Disease: What Is the Connection?
Published in Movement disorders (01-11-2022)“…Numerous studies have linked Parkinson′s disease (PD) with low levels of uric acid (UA). Low UA has been associated with the risk of developing PD, and its…”
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10
Rectal Microbiome Composition Correlates with Humoral Immunity to HIV-1 in Vaccinated Rhesus Macaques
Published in mSphere (11-12-2019)“…The microbiome is an integral and dynamic component of the host and is emerging as a critical determinant of immune responses; however, its influence on…”
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An Exploratory, Randomized, Double‐Blind Clinical Trial of Dipraglurant for Blepharospasm
Published in Movement disorders (01-04-2024)“…Background Blepharospasm is treated with botulinum toxin, but obtaining satisfactory results is sometimes challenging. Objective The aim is to conduct an…”
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12
Chronic SIV-induced neuroinflammation disrupts CCR7+CD4+ T cell immunosurveillance in the rhesus macaque brain
Published in The Journal of clinical investigation (01-05-2024)“…CD4 T cells survey and maintain immune homeostasis in the brain, yet their differentiation states and functional capabilities remain unclear. Our approach,…”
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13
Exploration of potential immune mechanisms in cervical dystonia
Published in Parkinsonism & related disorders (01-05-2024)“…Although there are many possible causes for cervical dystonia (CD), a specific etiology cannot be identified in most cases. Prior studies have suggested a…”
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14
Impact of Th1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques
Published in Journal of virology (28-02-2020)“…Generating durable humoral immunity through vaccination depends upon effective interactions of follicular helper T (Tfh) cells with germinal center (GC) B…”
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15
Abnormalities of neural stem cells in Lesch-Nyhan disease
Published in Journal of neurogenetics (03-07-2022)“…Lesch-Nyhan disease (LND) is a neurodevelopmental disorder caused by variants in the HPRT1 gene, which encodes the enzyme hypoxanthine-guanine phosphoribosyl…”
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16
Circulating integrin α 4 β 7 + CD4 T cells are enriched for proliferative transcriptional programs in HIV infection
Published in FEBS letters (01-09-2021)“…HIV preferentially infects α β CD4 T cells, forming latent reservoirs that contribute to HIV persistence during antiretroviral therapy. However, the properties…”
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Differential expression of striatal proteins in a mouse model of DOPA-responsive dystonia reveals shared mechanisms among dystonic disorders
Published in Molecular genetics and metabolism (01-08-2021)“…Dystonia is characterized by involuntary muscle contractions that cause debilitating twisting movements and postures. Although dysfunction of the basal…”
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Impact of T h 1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques
Published in Journal of virology (28-02-2020)“…Generating durable humoral immunity through vaccination depends upon effective interactions of follicular helper T (T ) cells with germinal center (GC) B…”
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19
CMAP: Complement Map Database
Published in Bioinformatics (15-07-2013)“…The human complement system is increasingly perceived as an intricate protein network of effectors, inhibitors and regulators that drives critical processes in…”
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20
Uric Acid in Parkinson Disease: What is the Connection?
Published in Movement disorders (03-09-2022)“…Numerous studies have linked Parkinson disease (PD) with low levels of uric acid (UA). Low UA has been associated with the risk of developing PD, and its…”
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