Search Results - "Dinan, T G"

Melancholic microbes: a link between gut microbiota and depression? by Dinan, T. G., Cryan, J. F.

“…There is a growing awareness of the potential for microbiota to influence gut‐brain communication in health and disease. A variety of strategies have been used…”
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Microbiota is essential for social development in the mouse by Desbonnet, L, Clarke, G, Shanahan, F, Dinan, T G, Cryan, J F

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The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner by Clarke, G, Grenham, S, Scully, P, Fitzgerald, P, Moloney, R D, Shanahan, F, Dinan, T G, Cryan, J F

“…Bacterial colonisation of the intestine has a major role in the post-natal development and maturation of the immune and endocrine systems. These processes are…”
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Bifidobacteria exert strain‐specific effects on stress‐related behavior and physiology in BALB/c mice by Savignac, H. M., Kiely, B., Dinan, T. G., Cryan, J. F.

“…Background Accumulating evidence suggests that commensal bacteria consumption has the potential to have a positive impact on stress‐related psychiatric…”
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Regulation of prefrontal cortex myelination by the microbiota by Hoban, A E, Stilling, R M, Ryan, F J, Shanahan, F, Dinan, T G, Claesson, M J, Clarke, G, Cryan, J F

“…The prefrontal cortex (PFC) is a key region implicated in a range of neuropsychiatric disorders such as depression, schizophrenia and autism. In parallel, the…”
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Genomics of schizophrenia: time to consider the gut microbiome? by Dinan, T G, Borre, Y E, Cryan, J F

“…Research into the genomics of schizophrenia promises much, but so far is resplendent with failures to replicate, and has yielded little of therapeutic…”
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The microbiome regulates amygdala-dependent fear recall by Hoban, A E, Stilling, R M, Moloney, G, Shanahan, F, Dinan, T G, Clarke, G, Cryan, J F

“…The amygdala is a key brain region that is critically involved in the processing and expression of anxiety and fear-related signals. In parallel, a growing…”
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Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression by Desbonnet, L, Garrett, L, Clarke, G, Kiely, B, Cryan, J.F, Dinan, T.G

“…Abstract The concept that intestinal microbial composition not only affects the health of the gut, but also influences centrally-mediated systems involved in…”
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Bifidobacterium longum 1714 as a translational psychobiotic: modulation of stress, electrophysiology and neurocognition in healthy volunteers by Allen, A P, Hutch, W, Borre, Y E, Kennedy, P J, Temko, A, Boylan, G, Murphy, E, Cryan, J F, Dinan, T G, Clarke, G

“…The emerging concept of psychobiotics—live microorganisms with a potential mental health benefit—represents a novel approach for the management of…”
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Review article: probiotics for the treatment of irritable bowel syndrome - focus on lactic acid bacteria by Clarke, G., Cryan, J. F., Dinan, T. G., Quigley, E. M.

“…Summary Background Irritable bowel syndrome (IBS) is a poorly understood, yet highly prevalent functional gastrointestinal disorder (FGID). The withdrawal, due…”
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A sustained hypothalamic-pituitary-adrenal axis response to acute psychosocial stress in irritable bowel syndrome by Kennedy, P J, Cryan, J F, Quigley, E M M, Dinan, T G, Clarke, G

“…Despite stress being considered a key factor in the pathophysiology of the functional gastrointestinal (GI) disorder irritable bowel syndrome (IBS), there is a…”
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Little things on which happiness depends: microRNAs as novel therapeutic targets for the treatment of anxiety and depression by O'Connor, R M, Dinan, T G, Cryan, J F

“…Anxiety and depression are devastating mental illnesses that are a significant public health concern. Selective serotonin-reuptake inhibitors are the…”
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High-fat diet selectively protects against the effects of chronic social stress in the mouse by Finger, B.C, Dinan, T.G, Cryan, J.F

“…Abstract Obesity and stress-related psychiatric disorders are frequently comorbid. However, our understanding of the relationship between diet, everyday life…”
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Antipsychotics and the gut microbiome: olanzapine-induced metabolic dysfunction is attenuated by antibiotic administration in the rat by Davey, K J, Cotter, P D, O'Sullivan, O, Crispie, F, Dinan, T G, Cryan, J F, O'Mahony, S M

“…The atypical antipsychotic olanzapine is often associated with serious metabolic side effects including weight gain and increased visceral fat. These adverse…”
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Priming for health: gut microbiota acquired in early life regulates physiology, brain and behaviour by Clarke, G, O'Mahony, SM, Dinan, TG, Cryan, JF

“…The infant gut microbiome is dynamic, and radical shifts in composition occur during the first 3 years of life. Disruption of these developmental patterns, and…”
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Cognitive performance in irritable bowel syndrome: evidence of a stress-related impairment in visuospatial memory by Kennedy, P J, Clarke, G, O'Neill, A, Groeger, J A, Quigley, E M M, Shanahan, F, Cryan, J F, Dinan, T G

“…Central nervous system (CNS) dysfunction is a prominent feature of the functional gastrointestinal (GI) disorder, irritable bowel syndrome (IBS). However, the…”
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MicroRNAs as biomarkers for major depression: a role for let-7b and let-7c by Gururajan, A, Naughton, M E, Scott, K A, O'Connor, R M, Moloney, G, Clarke, G, Dowling, J, Walsh, A, Ismail, F, Shorten, G, Scott, L, McLoughlin, D M, Cryan, J F, Dinan, T G

“…There is a growing emphasis in the field of psychiatry on the need to identify candidate biomarkers to aid in diagnosis and clinical management of depression,…”
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Altered peripheral toll‐like receptor responses in the irritable bowel syndrome by McKernan, D. P., Gaszner, G., Quigley, E. M., Cryan, J. F., Dinan, T. G.

“…Aliment Pharmacol Ther 2011; 33: 1045–1052 Summary Background  Irritable bowel syndrome (IBS) is a stress‐related disorder with disturbed brain‐gut…”
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Kynurenine pathway in psychosis: evidence of increased tryptophan degradation by Barry, S, Clarke, G, Scully, P, Dinan, TG

“…Abstract The kynurenine pathway of tryptophan degradation may serve to integrate disparate abnormalities heretofore identified in research aiming to elucidate…”
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The probiotic Bifidobacterium infantis 35624 displays visceral antinociceptive effects in the rat by Mckernan, D. P, Fitzgerald, P., Dinan, T. G., Cryan, J. F.

“…Background  Irritable bowel syndrome (IBS) is characterized by recurrent abdominal pain and altering bowel habit with a high percentage of patients displaying…”
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