Search Results - "Dina, Lev"

Outcome Prediction in Primary Resected Retroperitoneal Soft Tissue Sarcoma: Histology-Specific Overall Survival and Disease-Free Survival Nomograms Built on Major Sarcoma Center Data Sets by GRONCHI, Alessandro, MICELI, Rosalba, BONVALOT, Sylvie, MARIANI, Luigi, POLLOCK, Raphael E, SHURELL, Elizabeth, EILBER, Fritz C, EILBER, Frederick R, ANAYA, Daniel A, KATTAN, Michael W, HONORE, Charles, LEV, Dina C, COLOMBO, Chiara

“…Integration of numerous prognostic variables not included in the conventional staging of retroperitoneal soft tissue sarcomas (RPS) is essential in providing…”
Get full text

Multimodality Treatment of Desmoplastic Small Round Cell Tumor: Chemotherapy and Complete Cytoreductive Surgery Improve Patient Survival by Subbiah, Vivek, Lamhamedi-Cherradi, Salah-Eddine, Cuglievan, Branko, Menegaz, Brian A, Camacho, Pamela, Huh, Winston, Ramamoorthy, Vandhana, Anderson, Pete M, Pollock, Raphael E, Lev, Dina C, Qiao, Wei, McAleer, Mary Frances, Benjamin, Robert S, Patel, Shreyaskumar, Herzog, Cynthia E, Daw, Najat C, Feig, Barry W, Lazar, Alexander J, Hayes-Jordan, Andrea, Ludwig, Joseph A

“…Desmoplastic small round cell tumor (DSRCT), which harbors EWSR1-WT1 t(11;22)(p13:q12) chromosomal translocation, is an aggressive malignancy that typically…”
Get full text

Exosome-Derived miR-25-3p and miR-92a-3p Stimulate Liposarcoma Progression by Casadei, Lucia, Calore, Federica, Creighton, Chad J, Guescini, Michele, Batte, Kara, Iwenofu, O Hans, Zewdu, Abeba, Braggio, Danielle A, Bill, Kate Lynn, Fadda, Paolo, Lovat, Francesca, Lopez, Gonzalo, Gasparini, Pierluigi, Chen, James L, Kladney, Raleigh D, Leone, Gustavo, Lev, Dina, Croce, Carlo M, Pollock, Raphael E

“…Despite the development of combined modality treatments against liposarcoma in recent years, a significant proportion of patients respond only modestly to such…”
Get full text

ERG and FLI1 protein expression in epithelioid sarcoma by Stockman, David L, Hornick, Jason L, Deavers, Michael T, Lev, Dina C, Lazar, Alexander J, Wang, Wei-Lien

“…Epithelioid sarcoma is a rare, aggressive keratin-positive sarcoma that co-expresses CD34 in 50% of cases and may mimic an angiosarcoma. Recently, we have…”
Get full text

Locoregional Disease Patterns in Well-Differentiated and Dedifferentiated Retroperitoneal Liposarcoma: Implications for the Extent of Resection? by Tseng, William W., Madewell, John E., Wei, Wei, Somaiah, Neeta, Lazar, Alexander J., Ghadimi, Markus P., Hoffman, Aviad, Pisters, Peter W. T., Lev, Dina C., Pollock, Raphael E.

“…Background Well-differentiated (WD)/dedifferentiated (DD) liposarcoma is the most common soft tissue sarcoma of the retroperitoneum. The frequency of distant…”
Get full text

Detection and characterization of EWSR1/ATF1 and EWSR1/CREB1 chimeric transcripts in clear cell sarcoma (melanoma of soft parts) by Wang, Wei-Lien, Mayordomo, Empar, Zhang, Wenyong, Hernandez, Vivian S, Tuvin, Daniel, Garcia, Lisa, Lev, Dina C, Lazar, Alexander JF, López-Terrada, Dolores

“…Unlike melanoma, clear cell sarcoma harbors either a t(12;22)(q13;q12) recurrent translocation, resulting in an EWSR1/ATF1 chimeric gene, or less commonly a…”
Get full text

MicroRNA-182 drives metastasis of primary sarcomas by targeting multiple genes by Sachdeva, Mohit, Mito, Jeffrey K, Lee, Chang-Lung, Zhang, Minsi, Li, Zhizhong, Dodd, Rebecca D, Cason, David, Luo, Lixia, Ma, Yan, Van Mater, David, Gladdy, Rebecca, Lev, Dina C, Cardona, Diana M, Kirsch, David G

“…Metastasis causes most cancer deaths, but is incompletely understood. MicroRNAs can regulate metastasis, but it is not known whether a single miRNA can…”
Get full text

SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma by Bill, Kate Lynn J, Garnett, Jeannine, Meaux, Isabelle, Ma, XiaoYen, Creighton, Chad J, Bolshakov, Svetlana, Barriere, Cedric, Debussche, Laurent, Lazar, Alexander J, Prudner, Bethany C, Casadei, Lucia, Braggio, Danielle, Lopez, Gonzalo, Zewdu, Abbie, Bid, Hemant, Lev, Dina, Pollock, Raphael E

“…Dedifferentiated liposarcoma (DDLPS) is an aggressive malignancy that can recur locally or disseminate even after multidisciplinary care. Genetically amplified…”
Get full text

Clinical, Pathological, and Molecular Variables Predictive of Malignant Peripheral Nerve Sheath Tumor Outcome by CHANGYE ZOU, SMITH, Kerrington D, POLLOCK, Raphael E, LEV, Dina, JUN LIU, LAHAT, Guy, MYERS, Sarah, WANG, Wei-Lien, WEI ZHANG, MCCUTCHEON, Ian E, SLOPIS, John M, LAZAR, Alexander J

“…Improved staging systems for malignant peripheral nerve sheath tumor (MPNST) prognostication and management are needed. Consequently, we sought to identify…”
Get full text

MDM2 Derived from Dedifferentiated Liposarcoma Extracellular Vesicles Induces MMP2 Production from Preadipocytes by Casadei, Lucia, Calore, Federica, Braggio, Danielle A, Zewdu, Abeba, Deshmukh, Ameya A, Fadda, Paolo, Lopez, Gonzalo, Wabitsch, Martin, Song, Chi, Leight, Jennifer L, Grignol, Valerie P, Lev, Dina, Croce, Carlo M, Pollock, Raphael E

“…Dedifferentiated liposarcoma (DDLPS) is frequently diagnosed late, and patients typically respond poorly to treatments. DDLPS is molecularly characterized by…”
Get full text

Editor's Note: Genomic and Molecular Characterization of Malignant Peripheral Nerve Sheath Tumor Identifies the IGF1R Pathway as a Primary Target for Treatment by Yang, Jilong, Ylipää, Antti, Sun, Yan, Zheng, Hong, Chen, Kexin, Nykter, Matti, Trent, Jonathan, Ratner, Nancy, Lev, Dina C, Zhang, Wei

Get full text

The hepatocyte growth factor receptor as a potential therapeutic target for dedifferentiated liposarcoma by Bill, Kate Lynn J, Garnett, Jeannine, Ma, Xiaoyan, May, Caitlin D, Bolshakov, Svetlana, Lazar, Alexander J, Lev, Dina C, Pollock, Raphael E

“…Dedifferentiated liposarcomas (DDLPS) are highly resistant to conventional chemo- and radiotherapies, with surgical resection remaining the classic treatment…”
Get full text

NY-ESO-1 (CTAG1B) expression in mesenchymal tumors by Endo, Makoto, de Graaff, Marieke A, Ingram, Davis R, Lim, Simin, Lev, Dina C, Briaire-de Bruijn, Inge H, Somaiah, Neeta, Bovée, Judith VMG, Lazar, Alexander J, Nielsen, Torsten O

“…New York esophageal squamous cell carcinoma 1 (NY-ESO-1, CTAG1B) is a cancer-testis antigen and currently a focus of several targeted immunotherapeutic…”
Get full text

The role of surgical margin status in retroperitoneal sarcoma by Anaya, Daniel A., Lev, Dina C., Pollock, Raphael E.

“…Retroperitoneal sarcomas (RPS) represent approximately 15% of all soft tissue sarcomas (STS). Clinical and prognostic features as well as oncologic outcomes…”
Get full text

Noncontact measurement of elasticity for the detection of soft-tissue tumors using phase-sensitive optical coherence tomography combined with a focused air-puff system by Wang, Shang, Li, Jiasong, Manapuram, Ravi Kiran, Menodiado, Floredes M, Ingram, Davis R, Twa, Michael D, Lazar, Alexander J, Lev, Dina C, Pollock, Raphael E, Larin, Kirill V

“…We report on an optical noncontact method for the detection of soft-tissue tumors based on the measurement of their elasticity. A focused air-puff system is…”
Get more information

Experimental models of undifferentiated pleomorphic sarcoma and malignant peripheral nerve sheath tumor by Bhalla, Angela D., Landers, Sharon M., Singh, Anand K., Landry, Jace P., Yeagley, Michelle G., Myerson, Gabryella S. B., Delgado-Baez, Cristian B., Dunnand, Stephanie, Nguyen, Theresa, Ma, Xiaoyan, Bolshakov, Svetlana, Menegaz, Brian A., Lamhamedi-Cherradi, Salah-Eddine, Mao, Xizeng, Song, Xingzhi, Lazar, Alexander J., McCutcheon, Ian E., Slopis, John M., Ludwig, Joseph A., Lev, Dina C., Rai, Kunal, Torres, Keila E.

“…Undifferentiated pleomorphic sarcoma (UPS) and malignant peripheral nerve sheath tumor (MPNST) are aggressive soft tissue sarcomas that do not respond well to…”
Get full text

Genomic and molecular characterization of malignant peripheral nerve sheath tumor identifies the IGF1R pathway as a primary target for treatment by Yang, Jilong, Ylipää, Antti, Sun, Yan, Zheng, Hong, Chen, Kexin, Nykter, Matti, Trent, Jonathan, Ratner, Nancy, Lev, Dina C, Zhang, Wei

“…Malignant peripheral nerve sheath tumor (MPNST) is a rare sarcoma that lacks effective therapeutic strategies. We gain insight into the most recurrent…”
Get full text

Vimentin is a novel anti-cancer therapeutic target; insights from in vitro and in vivo mice xenograft studies by Lahat, Guy, Zhu, Quan-Sheng, Huang, Kai-Lieh, Wang, Suizhao, Bolshakov, Svetlana, Liu, Jeffery, Torres, Keila, Langley, Robert R, Lazar, Alexander J, Hung, Mien Chie, Lev, Dina

“…Vimentin is a ubiquitous mesenchymal intermediate filament supporting mechano-structural integrity of quiescent cells while participating in adhesion,…”
Get full text

A Small-Molecule Inhibitor Targeting the Mitotic Spindle Checkpoint Impairs the Growth of Uterine Leiomyosarcoma by WEIWEI SHAN, AKINFENWA, Patricia Y, SAVANNAH, Kari B, KOLOMEYEVSKAYA, Nonna, LAUCIRICA, Rudolfo, THOMAS, Dafydd G, ODUNSI, Kunle, CREIGHTON, Chad J, LEV, Dina C, ANDERSON, Matthew L

“…Uterine leiomyosarcoma (ULMS) is a poorly understood cancer with few effective treatments. This study explores the molecular events involved in ULMS with the…”
Get full text

Vascular tumors have increased p70 S6-kinase activation and are inhibited by topical rapamycin by Du, Wa, Gerald, Damien, Perruzzi, Carole A, Rodriguez-Waitkus, Paul, Enayati, Ladan, Krishnan, Bhuvaneswari, Edmonds, Joseph, Hochman, Marcelo L, Lev, Dina C, Phung, Thuy L

“…Vascular tumors are endothelial cell neoplasms whose cellular and molecular mechanisms, leading to tumor formation, are poorly understood, and current…”
Get full text