Search Results - "Dimura, Mykola"

Resolving dynamics and function of transient states in single enzyme molecules by Sanabria, Hugo, Rodnin, Dmitro, Hemmen, Katherina, Peulen, Thomas-Otavio, Felekyan, Suren, Fleissner, Mark R., Dimura, Mykola, Koberling, Felix, Kühnemuth, Ralf, Hubbell, Wayne, Gohlke, Holger, Seidel, Claus A. M.

“…We use a hybrid fluorescence spectroscopic toolkit to monitor T4 Lysozyme (T4L) in action by unraveling the kinetic and dynamic interplay of the conformational…”
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Automated and optimally FRET-assisted structural modeling by Dimura, Mykola, Peulen, Thomas-Otavio, Sanabria, Hugo, Rodnin, Dmitro, Hemmen, Katherina, Hanke, Christian A., Seidel, Claus A. M., Gohlke, Holger

“…FRET experiments can provide state-specific structural information of complex dynamic biomolecular assemblies. However, to overcome the sparsity of FRET…”
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Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α by Kilic, Sinan, Felekyan, Suren, Doroshenko, Olga, Boichenko, Iuliia, Dimura, Mykola, Vardanyan, Hayk, Bryan, Louise C., Arya, Gaurav, Seidel, Claus A. M., Fierz, Beat

“…The dynamic architecture of chromatin fibers, a key determinant of genome regulation, is poorly understood. Here, we employ multimodal single-molecule Förster…”
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Dynamics of the nucleosomal histone H3 N-terminal tail revealed by high precision single-molecule FRET by Lehmann, Kathrin, Felekyan, Suren, Kühnemuth, Ralf, Dimura, Mykola, Tóth, Katalin, Seidel, Claus A M, Langowski, Jörg

“…Abstract Chromatin compaction and gene accessibility are orchestrated by assembly and disassembly of nucleosomes. Although the disassembly process was widely…”
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Integrative dynamic structural biology unveils conformers essential for the oligomerization of a large GTPase by Peulen, Thomas-O, Hengstenberg, Carola S, Biehl, Ralf, Dimura, Mykola, Lorenz, Charlotte, Valeri, Alessandro, Folz, Julian, Hanke, Christian A, Ince, Semra, Vöpel, Tobias, Farago, Bela, Gohlke, Holger, Klare, Johann P, Stadler, Andreas M, Seidel, Claus A M, Herrmann, Christian

“…Guanylate binding proteins (GBPs) are soluble dynamin-like proteins that undergo a conformational transition for GTP-controlled oligomerization and disrupt…”
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FRET-Assisted Protein Structure Postdiction of CASP13 Targets by Dimura, Mykola, Gohlke, Holger, Seidel, Claus A.

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Quantitative FRET studies and integrative modeling unravel the structure and dynamics of biomolecular systems by Dimura, Mykola, Peulen, Thomas O, Hanke, Christian A, Prakash, Aiswaria, Gohlke, Holger, Seidel, Claus AM

“…[Display omitted] •Hybrid-FRET on rails automates FRET-based integrative structural modeling.•Automated experiment design assures highest structural quality…”
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From FRET Measurements to Database Deposition of Integrative Structural Models by Hanke, Christian A., Vardanyan, Hayk, Dimura, Mykola, Seidel, Claus A.M.

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Protein Structure Determination by High-Precision FRET and Molecular Modeling by Dimura, Mykola, Peulen, Thomas, Gohlke, Holger, Seidel, Claus A.M.

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Integrative Dynamic Structural Biology with Fluorescence Spectroscopy by Seidel, Claus A.M., Dimura, Mykola, Sanabria, Hugo, Hemmen, Katherina, Peulen, Thomas-Otavio, Rodnin, Dmitro, Gohlke, Holger

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Automated and Optimally FRET-Assisted Structural Modeling by Dimura, Mykola, Ottavio Peulen, Thomas, Sanabria, Hugo, Rodnin, Dmitro, Hemmen, Katherina, Seidel, Claus A.M., Gohlke, Holger

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Multiple Interaction Modes of the Nucleosomal Histone H3 N-Terminal Tail Revealed by High Precision Single-Molecule FRET by Lehmann, Kathrin, Felekyan, Suren, Kühnemuth, Ralf, Dimura, Mykola, Tóth, Katalin, Seidel, Claus A.M.

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Integrative Molecular Modelling of Biomolecules Guided by FRET Experiments by Hanke, Christian A., Dimura, Mykola, Peulen, Thomas-Otavio, Gohlke, Holger, Seidel, Claus A.M.

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Resolution of Maximum Entropy Method-Derived Posterior Conformational Ensembles of a Flexible System Probed by FRET and Molecular Dynamics Simulations by Dittrich, Jonas, Popara, Milana, Kubiak, Jakub, Dimura, Mykola, Schepers, Bastian, Verma, Neha, Schmitz, Birte, Dollinger, Peter, Kovacic, Filip, Jaeger, Karl-Erich, Seidel, Claus A. M., Peulen, Thomas-Otavio, Gohlke, Holger

“…Maximum entropy methods (MEMs) determine posterior distributions by combining experimental data with prior information. MEMs are frequently used to reconstruct…”
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Toolkit for Multi-Conformation Biomolecular Structure Determination by High-Precision FRET and Molecular Simulations by Dimura, Mykola, Kalinin, Stanislav, Peulen, Thomas, Gohlke, Holger, Seidel, Claus A.M.

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Toolkit for Multi-Conformation Biomolecular Structure Determination by High-Precision FRET and Molecular Simulations by Dimura, Mykola, Kalinin, Stanislav, Peulen, Thomas, Gohlke, Holger, Seidel, Claus A.M.

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Structural assemblies of the di- and oligomeric G-protein coupled receptor TGR5 in live cells: an MFIS-FRET and integrative modelling study by Greife, Annemarie, Felekyan, Suren, Ma, Qijun, Gertzen, Christoph G. W., Spomer, Lina, Dimura, Mykola, Peulen, Thomas O., Wöhler, Christina, Häussinger, Dieter, Gohlke, Holger, Keitel, Verena, Seidel, Claus A. M.

“…TGR5 is the first identified bile acid-sensing G-protein coupled receptor, which has emerged as a potential therapeutic target for metabolic disorders. So far,…”
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Mapping Motions and Structure to a State Necessary for Oligomerization of a Large GTPase: A Joint SAXS, NSE, EPR and FRET Study by Peulen, Thomas-Otavio, Hengstenberg, Carola S., Biehl, Ralf, Dimura, Mykola, Valeri, Alessandro, Ince, Semra, Vöpel, Tobias, Farago, Bela, Gohlke, Holger, Herrmann, Christian, Klare, Johann, Stadler, Andreas, Seidel, Claus A.M.

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Automated and optimally FRET-assisted structural modeling by Dimura, Mykola, Peulen, Thomas O, Sanabria, Hugo, Rodnin, Dmitro, Hemmen, Katherina, Seidel, Claus A. M, Gohlke, Holger

“…FRET experiments can yield state-specific structural information on complex dynamic biomolecular assemblies. However, FRET experiments need to be combined with…”
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Integrative dynamic structural biology unveils conformers essential for the oligomerization of a large GTPase by Peulen, Thomas-Otavio, Hengstenberg, Carola S, Biehl, Ralf, Dimura, Mykola, Lorenz, Charlotte, Valeri, Alessandro, Ince, Semra, Vöpel, Tobias, Faragó, Bela, Gohlke, Holger, Klare, Johann P, Stadler, Andreas M, Seidel, Claus A. M, Herrmann, Christian

“…Guanylate binding proteins (GBPs) are soluble dynamin-like proteins with structured domains that undergo a conformational transition for GTP-controlled…”
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