Search Results - "Dimond, R L"

Visualization of antigenic proteins on Western blots by Knecht, D A, Dimond, R L

“…A new technique for the detection of antibodies bound to proteins blotted onto nitrocellulose paper was developed. The method is rapid, sensitive, and does not…”
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Inhibition of Early but Not Late Proteolytic Processing Events Leads to the Missorting and Oversecretion of Precursor Forms of Lysosomal Enzymes in Dictyostelium discoideum by Richardson, Jan M., Woychik, Nancy A., Ebert, David L., Dimond, Randall L., Cardelli, James A.

“…Lysosomal enzymes are initially synthesized as precursor polypeptides which are proteolytically cleaved to generate mature forms of the enzymatically active…”
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Antigenic determinants shared by lysosomal proteins of Dictyostelium discoideum. Characterization using monoclonal antibodies and isolation of mutations affecting the determinant by Knecht, D A, Dimond, R L, Wheeler, S, Loomis, W F

“…Polyclonal antisera raised against a single lysosomal enzyme from Dictyostelium discoideum will cross-react with other lysosomal proteins due to the presence…”
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Lysosomal Enzymes in Dictyostelium discoideum Are Transported to Lysosomes at Distinctly Different Rates by Cardelli, James A., Golumbeski, George S., Dimond, Randall L.

“…We are investigating the molecular mechanisms involved in the localization of lysosomal enzymes in Dictyostelium discoideum, an organism that lacks any…”
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A Dictyostelium discoideum Mutant That Missorts and Oversecretes Lysosomal Enzyme Precursors Is Defective in Endocytosis by Ebert, David L., Freeze, Hudson H., Richardson, Jan, Dimond, Randall L., Cardelli, James A.

“…A mutant strain of Dictyostelium discoideum, HMW570, oversecretes several lysosomal enzyme activities during growth. Using a radiolable pulse-chase protocol,…”
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Sulfated oligosaccharides block antibodies to many Dictyostelium discoideum acid hydrolases by Freeze, H H, Mierendorf, R C, Wunderlich, R, Dimond, R L

“…The lysosomal hydrolases of the cellular slime mold, Dictyostelium discoideum, possess a common posttranslational modification which is extremely antigenic in…”
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A single mutation prevents the normal intracellular transport of multiple lysosomal proteins from the rough endoplasmic reticulum by Woychik, N.A., Dimond, R.L.

“…Dictyostelium discoideum strain HMW-426 has been previously shown to be defective in the proteolytic processing of the lysosomal enzyme precursor to…”
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Biosynthesis of two developmentally distinct acid phosphatase isozymes in Dictyostelium discoideum by Bennett, V D, Dimond, R L

“…The presence of a common antigenic determinant on the Dictyostelium discoideum acid phosphatase isozyme 1 (ap 1), and the absence of this determinant on the…”
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A conformationally altered precursor to the lysosomal enzyme alpha-mannosidase accumulates in the endoplasmic reticulum in a mutant strain of Dictyostelium discoideum by Woychik, N A, Cardelli, J A, Dimond, R L

“…The mutant strain of Dictyostelium discoideum, HMW-437, contains a mutation in the structural gene coding for the lysosomal enzyme alpha-mannosidase. Unlike…”
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Synthesis of related forms of the lysosomal enzyme alpha-mannosidase in Dictyostelium discoideum by Mierendorf, R C, Cardelli, J A, Livi, G P, Dimond, R L

“…Purified lysosomal alpha-mannosidase from the cellular slime mold, Dictyostelium discoideum, is composed of two subunits of Mr = 58,000 and 60,000 as revealed…”
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Lysosomal enzymes possess a common antigenic determinant in the cellular slime mold, Dictyostelium discoideum [Fungi] by Knecht, D.A, Dimond, R.L

“…Antisera have been prepared against two lysosomal enzymes of the cellular slime mold, Dictyostelium discoideum. The two purified enzyme preparations used for…”
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Lysosomal enzyme secretory mutants of Dictyostelium discoideum by Ebert, D.L, Jordan, K.B, Dimond, R.L

“…Dictyostelium discoideum secretes a number of lysosomal enzymes during axenic growth and upon suspension in a low ionic strength, non-nutrient buffer (standard…”
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Secretion of lysosomal enzymes in the cellular slime mold, Dictyostelium discoideum by Dimond, R L, Burns, R A, Jordan, K B

“…One group of enzymes, including N-Acetylglucosaminidase, alpha -mannosidase, beta -glucosidase, beta -galactosidase-1, and beta -glucosidase-1 are very…”
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Purification and characterization of a staphylococcal epidermolytic toxin by Dimond, R L, Wuepper, K D

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Biogenesis of lysosomal enzymes in the alpha-glucosidase II-deficient modA mutant of Dictyostelium discoideum: retention of alpha-1,3-linked glucose on N-linked oligosaccharides delays intracellular transport but does not alter sorting of alpha-mannosidase or beta-glucosidase by Ebert, D L, Bush, J M, Dimond, R L, Cardelli, J A

“…The endoplasmic reticulum-localized enzyme alpha-glucosidase II is responsible for removing the two alpha-1,3-linked glucose residues from N-linked…”
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The use of tolerization in the production of monoclonal antibodies against minor antigenic determinants by Golumbeski, Jr, G S, Dimond, R L

“…An initial attempt to prepare monoclonal antibodies specific for the Dictyostelium discoideum lysosomal enzyme beta-glucosidase was unsuccessful. All of the…”
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Characterization and distribution of multiple antigens on N-linked oligosaccharides of Dictyostelium discoideum proteins by Judelson, H S, Freeze, H H, Dimond, R L

“…Monoclonal antibodies were prepared against a mixture of purified lysosomal enzymes from Dictyostelium discoideum. Three classes of antibodies were found which…”
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Developmentally regulated expression of temporally distinct β-glucosidase isozymes in Dictyostelium discoideum by Golumbeski, George S., Dimond, Randall L.

“…During development of Dictyostelium discoideum, the cellular specific activity of β-glucosidase increases before aggregation, declines to low levels during…”
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A late developmental change in lysosomal enzyme sulfation specific to newly synthesized proteins in Dictyostelium discoideum by Livi, George P., Woychik, Nancy A., Dimond, Randall L.

“…During development in Dictyostelium discoideum, several lysosomal glycosidases undergo changes in post-translational modification that are thought to involve…”
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Initial events involved in the synthesis of the lysosomal enzyme alpha-mannosidase in Dictyostelium discoideum by Cardelli, J A, Mierendorf, Jr, R C, Dimond, R L

“…In Dictyostelium discoideum the lysosomal enzyme alpha-mannosidase is initially synthesized in vivo as a 140,000 Mr protein which is subsequently processed…”
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