Search Results - "Dimintiyanova, K. P."

Increased Axon Initial Segment Length Results in Increased Na+ Currents in Spinal Motoneurones at Symptom Onset in the G127X SOD1 Mouse Model of Amyotrophic Lateral Sclerosis by Jørgensen, H.S., Jensen, D.B., Dimintiyanova, K.P., Bonnevie, V.S., Hedegaard, A., Lehnhoff, J., Moldovan, M., Grondahl, L., Meehan, C.F.

“…•In vivo electrophysiological recordings were made in symptomatic G127X SOD1 mice.•There were no deficits in repetitive firing in motoneurones in G127X…”
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Shorter axon initial segments do not cause repetitive firing impairments in the adult presymptomatic G127X SOD-1 Amyotrophic Lateral Sclerosis mouse by Bonnevie, V. S., Dimintiyanova, K. P., Hedegaard, A., Lehnhoff, J., Grøndahl, L., Moldovan, M., Meehan, C. F.

“…Increases in axonal sodium currents in peripheral nerves are some of the earliest excitability changes observed in Amyotrophic Lateral Sclerosis (ALS)…”
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Intramuscular Botulinum toxin A injections induce central changes to axon initial segments and cholinergic boutons on spinal motoneurones in rats by Jensen, D. B., Klingenberg, S., Dimintiyanova, K. P., Wienecke, J., Meehan, C. F.

“…Intramuscular injections of botulinum toxin block pre-synaptic cholinergic release at neuromuscular junctions producing a temporary paralysis of affected motor…”
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