Search Results - "Dimeglio, A."
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COVID-19 and Type 1 Diabetes: Addressing Concerns and Maintaining Control
Published in Diabetes care (01-09-2021)“…The worldwide outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been an unprecedented pandemic. Early on, even as the signs and…”
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100 years of insulin: celebrating the past, present and future of diabetes therapy
Published in Nature medicine (01-07-2021)“…The year 2021 marks the centennial of Banting and Best’s landmark description of the discovery of insulin. This discovery and insulin’s rapid clinical…”
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Current state of type 1 diabetes treatment in the U.S.: updated data from the T1D Exchange clinic registry
Published in Diabetes care (01-06-2015)“…To examine the overall state of metabolic control and current use of advanced diabetes technologies in the U.S., we report recent data collected on individuals…”
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Diagnosis and Management of Osteopetrosis: Consensus Guidelines From the Osteopetrosis Working Group
Published in The journal of clinical endocrinology and metabolism (01-09-2017)“…Abstract Background Osteopetrosis encompasses a group of rare metabolic bone diseases characterized by impaired osteoclast activity or development, resulting…”
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Racial Differences in the Relationship of Glucose Concentrations and Hemoglobin A1c Levels
Published in Annals of internal medicine (18-07-2017)“…Debate exists as to whether the higher hemoglobin A1c (HbA1c) levels observed in black persons than in white persons are due to worse glycemic control or…”
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Prevalence of detectable C-Peptide according to age at diagnosis and duration of type 1 diabetes
Published in Diabetes care (01-03-2015)“…It is generally accepted that complete β-cell destruction eventually occurs in individuals with type 1 diabetes, which has implications for treatment…”
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Global Consensus Recommendations on Prevention and Management of Nutritional Rickets
Published in Hormone research in paediatrics (2016)“…Vitamin D and calcium deficiencies are common worldwide, causing nutritional rickets and osteomalacia, which have a major impact on health, growth, and…”
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ISPAD Clinical Practice Consensus Guidelines 2022: Exercise in children and adolescents with diabetes
Published in Pediatric diabetes (01-12-2022)Get full text
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Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial
Published in The Lancet (British edition) (2011)“…Summary Background The immunopathogenesis of type 1 diabetes mellitus is associated with T-cell autoimmunity. To be fully active, immune T cells need a…”
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Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials
Published in The Lancet (British edition) (01-06-2013)“…Summary Background Innate immunity contributes to the pathogenesis of autoimmune diseases, such as type 1 diabetes, but until now no randomised, controlled…”
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Global Consensus Recommendations on Prevention and Management of Nutritional Rickets
Published in The journal of clinical endocrinology and metabolism (01-02-2016)“…Background: Vitamin D and calcium deficiencies are common worldwide, causing nutritional rickets and osteomalacia, which have a major impact on health, growth,…”
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ISPAD Clinical Practice Consensus Guidelines 2022: Managing diabetes in preschoolers
Published in Pediatric diabetes (01-12-2022)Get full text
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Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial
Published in The Lancet (British edition) (23-07-2011)“…Summary Background Glutamic acid decarboxylase (GAD) is a major target of the autoimmune response that occurs in type 1 diabetes mellitus. In animal models of…”
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Cause or effect? A review of clinical data demonstrating beta cell dysfunction prior to the clinical onset of type 1 diabetes
Published in Molecular metabolism (Germany) (01-09-2019)“…Limited successes of conventional approaches to type 1 diabetes (T1D) prevention and treatment have highlighted the need for improved understanding of risk…”
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Evaluating the effect of prebiotics on the gut microbiome profile and β cell function in youth with newly diagnosed type 1 diabetes: protocol of a pilot randomized controlled trial
Published in Pilot and feasibility studies (25-08-2023)“…Data show that disturbances in the gut microbiota play a role in glucose homeostasis, type 1 diabetes (T1D) risk and progression. The prebiotic high amylose…”
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Growth differentiation factor 15 (GDF15) elevation in children with newly diagnosed cancer
Published in Frontiers in oncology (11-12-2023)“…Growth differentiation factor 15 (GDF15), an inflammatory marker and mediator of adult cancer cachexia, remains largely unexplored in children. GDF15 increases…”
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Growth in Pediatric Orthopaedics
Published in Journal of pediatric orthopaedics (01-07-2001)Get full text
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Advances in the Classification and Treatment of Osteogenesis Imperfecta
Published in Current osteoporosis reports (01-02-2016)“…Osteogenesis imperfecta (OI) is a rare disorder of type 1 collagen with 13 currently identified types attributable to inherited abnormalities in type 1…”
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Type 1 diabetes
Published in The Lancet (British edition) (16-06-2018)“…Type 1 diabetes is a chronic autoimmune disease characterised by insulin deficiency and resultant hyperglycaemia. Knowledge of type 1 diabetes has rapidly…”
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In Vitro Hyperglycemia or a Diabetic Intrauterine Environment Reduces Neonatal Endothelial Colony-Forming Cell Numbers and Function
Published in Diabetes (New York, N.Y.) (01-03-2008)“…In Vitro Hyperglycemia or a Diabetic Intrauterine Environment Reduces Neonatal Endothelial Colony-Forming Cell Numbers and Function David A. Ingram 1 , 2 ,…”
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