Search Results - "Dima, Mariavittoria"

Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors by Antico Arciuch, Valeria G, Russo, Marika A, Dima, Mariavittoria, Kang, Kristy S, Dasrath, Florence, Liao, Xiao-Hui, Refetoff, Samuel, Montagna, Cristina, Di Cristofano, Antonio

“…Anaplastic thyroid carcinoma (ATC) is the most aggressive form of thyroid cancer, and often derives from pre-existing well-differentiated tumors. Despite a…”
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High periostin expression correlates with aggressiveness in papillary thyroid carcinomas by Puppin, Cinzia, Fabbro, Dora, Dima, Mariavittoria, Di Loreto, Carla, Puxeddu, Efisio, Filetti, Sebastiano, Russo, Diego, Damante, Giuseppe

“…Periostin is a mesenchyme-specific gene product, which acts as an adhesion molecule during bone formation and supports osteoblastic cell line attachment and…”
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Epigenetic-related gene expression profile in medullary thyroid cancer revealed the overexpression of the histone methyltransferases EZH2 and SMYD3 in aggressive tumours by Sponziello, Marialuisa, Durante, Cosimo, Boichard, Amelie, Dima, Mariavittoria, Puppin, Cinzia, Verrienti, Antonella, Tamburrano, Giulia, Di Rocco, Giorgio, Redler, Adriano, Lacroix, Ludovic, Bidart, Jean-Michel, Schlumberger, Martin, Damante, Giuseppe, Russo, Diego, Filetti, Sebastiano

“…•Epigenetic machinery may be involved in the progression of MTC.•A common gene expression pattern of the more aggressive tumours was revealed.•EZH2 and SMYD3…”
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Abstract LB-152: Characterization of the first mouse model of anaplastic thyroid carcinoma by Dima, Mariavittoria, Cristofano, Antonio Di

“…Although anaplastic thyroid carcinoma is a rather uncommon malignancy, it accounts for the vast majority of deaths from thyroid cancer. Despite considerable…”
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Abstract 5075: PI3K activation restores KrasG12D oncogenic ability in a mouse model of follicular thyroid cancer by directly opposing multiple Kras-initiated negative feedback signals by Dima, Mariavittoria, Baker, Kristen, Cristofano, Antonio Di

“…Activating mutations of Ras family members and aberrant activation of the PI3K/AKT pathway are quite common in thyroid cancer originating from the follicular…”
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Molecular profiles of cancer stem-like cell populations in aggressive thyroid cancers by Dima, Mariavittoria, Pecce, Valeria, Biffoni, Mauro, Di Gioia, Cira Rosaria Tiziana, Tallini, Giovanni, Biffoni, Marco, Rosignolo, Francesca, Verrienti, Antonella, Sponziello, Marialuisa, Damante, Giuseppe, Russo, Diego, Durante, Cosimo

“…A substantial proportion of patients with advanced thyroid carcinoma fail to respond to or at some point become refractory to conventional therapies. This…”
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Cross-talk between PI3K and estrogen in the mouse thyroid predisposes to the development of follicular carcinomas with a higher incidence in females by Antico-Arciuch, V G, Dima, M, Liao, X-H, Refetoff, S, Di Cristofano, A

“…It is well known that thyroid disease is more frequent in women than in men; however, the molecular basis for this gender-based difference is still poorly…”
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Establishment and characterization of cell lines from a novel mouse model of poorly differentiated thyroid carcinoma: powerful tools for basic and preclinical research by Dima, Mariavittoria, Miller, Kelly A, Antico-Arciuch, Valeria Gabriela, Di Cristofano, Antonio

“…Poorly differentiated and anaplastic thyroid carcinomas have a rather poor prognosis. The development of relevant model systems to unravel in vitro and in vivo…”
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Increased expression of pro-angiogenic factors and vascularization in thyroid hyperfunctioning adenomas with and without TSH receptor activating mutations by Celano, Marilena, Sponziello, Marialuisa, Tallini, Giovanni, Maggisano, Valentina, Bruno, Rocco, Dima, Mariavittoria, Di Oto, Enrico, Redler, Adriano, Durante, Cosimo, Sacco, Rosario, Filetti, Sebastiano, Russo, Diego

“…Autonomously functioning thyroid nodules (AFTN) are known to receive an increased blood influx necessary to sustain their high rate of growth and hormone…”
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Prohibitin is overexpressed in papillary thyroid carcinomas bearing the BRAF(V600E) mutation by Franzoni, Alessandra, Dima, Mariavittoria, D'Agostino, Maria, Puppin, Cinzia, Fabbro, Dora, Loreto, Carla Di, Pandolfi, Maura, Puxeddu, Efisio, Moretti, Sonia, Celano, Marilena, Bruno, Rocco, Filetti, Sebastiano, Russo, Diego, Damante, Giuseppe

“…Prohibitin (PHB) is a multifunctional protein that is localized in different intracellular sites. PHB may exert different roles in tumorigenesis, having either…”
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