Search Results - "Dilweg, Ivar W."

Xrn1-resistant RNA motifs are disseminated throughout the RNA virome and are able to block scanning ribosomes by Dilweg, Ivar W., Peer, Jasper, Olsthoorn, René C. L.

“…RNAs that are able to prevent degradation by the 5’–3’ exoribonuclease Xrn1 have emerged as crucial structures during infection by an increasing number of RNA…”
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Investigating the correlation between Xrn1-resistant RNAs and frameshifter pseudoknots by Dilweg, Ivar W., Oskam, Megan G., Overbeek, Sophie, Olsthoorn, René C.L.

“…Xrn1-resistant RNA structures are multifunctional elements employed by an increasing number of RNA viruses. One of such elements is the coremin motif,…”
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Structural features of an Xrn1-resistant plant virus RNA by Dilweg, Ivar W., Gultyaev, Alexander P., Olsthoorn, René C.

“…Xrn1 is a major 5ʹ-3ʹ exoribonuclease involved in the RNA metabolism of many eukaryotic species. RNA viruses have evolved ways to thwart Xrn1 in order to…”
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All genera of Flaviviridae host a conserved Xrn1-resistant RNA motif by Dilweg, Ivar W., Savina, Anya, Köthe, Susanne, Gultyaev, Alexander P., Bredenbeek, Peter J., Olsthoorn, René C.L.

“…After infection by flaviviruses like Zika and West Nile virus, eukaryotic hosts employ the well-conserved endoribonuclease Xrn1 to degrade the viral genomic…”
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Xrn1-resistant RNA structures are well-conserved within the genus flavivirus by Dilweg, Ivar W., Bouabda, Assia, Dalebout, Tim, Gultyaev, Alexander P., Bredenbeek, Peter J., Olsthoorn, R. C. L.

“…Subgenomic RNAs are produced by several RNA viruses through incomplete degradation of their genomic RNA by the exoribonuclease Xrn1, and have been shown to be…”
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