Search Results - "Dillon, Stephanie M"

Inside Out: HIV, the Gut Microbiome, and the Mucosal Immune System by Liu, Jay, Williams, Brett, Frank, Daniel, Dillon, Stephanie M, Wilson, Cara C, Landay, Alan L

“…The components of the human gut microbiome have been found to influence a broad array of pathologic conditions ranging from heart disease to diabetes and even…”
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Interferon-α Subtypes in an Ex Vivo Model of Acute HIV-1 Infection: Expression, Potency and Effector Mechanisms by Harper, Michael S, Guo, Kejun, Gibbert, Kathrin, Lee, Eric J, Dillon, Stephanie M, Barrett, Bradley S, McCarter, Martin D, Hasenkrug, Kim J, Dittmer, Ulf, Wilson, Cara C, Santiago, Mario L

“…HIV-1 is transmitted primarily across mucosal surfaces and rapidly spreads within the intestinal mucosa during acute infection. The type I interferons (IFNs)…”
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Commensal and Pathogenic Bacteria Indirectly Induce IL-22 but Not IFNγ Production From Human Colonic ILC3s via Multiple Mechanisms by Castleman, Moriah J, Dillon, Stephanie M, Purba, Christine M, Cogswell, Andrew C, Kibbie, Jon J, McCarter, Martin D, Santiago, Mario L, Barker, Edward, Wilson, Cara C

“…Innate lymphoid cells (ILCs) are a diverse family of cells that play critical roles in mucosal immunity. One subset of the ILC family, Group 3 ILCs (ILC3s),…”
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Qualitative Differences Between the IFNα subtypes and IFNβ Influence Chronic Mucosal HIV-1 Pathogenesis by Guo, Kejun, Shen, Guannan, Kibbie, Jon, Gonzalez, Tania, Dillon, Stephanie M, Smith, Harry A, Cooper, Emily H, Lavender, Kerry, Hasenkrug, Kim J, Sutter, Kathrin, Dittmer, Ulf, Kroehl, Miranda, Kechris, Katerina, Wilson, Cara C, Santiago, Mario L

“…The Type I Interferons (IFN-Is) are innate antiviral cytokines that include 12 different IFNα subtypes and IFNβ that signal through the IFN-I receptor (IFNAR),…”
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Enteric bacteria induce IFNγ and Granzyme B from human colonic Group 1 Innate Lymphoid Cells by Castleman, Moriah J., Dillon, Stephanie M., Purba, Christine, Cogswell, Andrew C., McCarter, Martin, Barker, Edward, Wilson, Cara

“…Group 1 Innate Lymphoid Cells (which include Natural Killer cells and ILC1s) aid in gut anti-bacterial defense through the production of IFNγ, which is…”
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The transcriptome of HIV-1 infected intestinal CD4+ T cells exposed to enteric bacteria by Yoder, Alyson C, Guo, Kejun, Dillon, Stephanie M, Phang, Tzu, Lee, Eric J, Harper, Michael S, Helm, Karen, Kappes, John C, Ochsenbauer, Christina, McCarter, Martin D, Wilson, Cara C, Santiago, Mario L

“…Global transcriptome studies can help pinpoint key cellular pathways exploited by viruses to replicate and cause pathogenesis. Previous data showed that…”
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Granzyme B+ CD4 T cells accumulate in the colon during chronic HIV-1 infection by Dillon, Stephanie M., Mickens, Kaylee L., Thompson, Tezha A., Cooper, Emily H., Nesladek, Sabrina, Christians, Allison J., Castleman, Moriah, Guo, Kejun, Wood, Cheyret, Frank, Daniel N., Kechris, Katerina, Santiago, Mario L., Wilson, Cara C.

“…Chronic HIV-1 infection results in the sustained disruption of gut homeostasis culminating in alterations in microbial communities (dysbiosis) and increased…”
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Reduced immune-regulatory molecule expression on human colonic memory CD4 T cells in older adults by Dillon, Stephanie M, Thompson, Tezha A, Christians, Allison J, McCarter, Martin D, Wilson, Cara C

“…The etiology of the low-level chronic inflammatory state associated with aging is likely multifactorial, but a number of animal and human studies have…”
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Human intestinal lamina propria CD1c+ dendritic cells display an activated phenotype at steady state and produce IL-23 in response to TLR7/8 stimulation by Dillon, Stephanie M, Rogers, Lisa M, Howe, Rawleigh, Hostetler, Lydia A, Buhrman, Jonathan, McCarter, Martin D, Wilson, Cara C

“…Intestinal dendritic cells (DCs) play key roles in mediating tolerance to commensal flora and inflammatory responses against mucosal pathogens. The mechanisms…”
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The gut microbiome and HIV-1 pathogenesis: a two-way street by Dillon, Stephanie M, Frank, Daniel N, Wilson, Cara C

“…HIV-1 infection is associated with substantial damage to the gastrointestinal tract resulting in structural impairment of the epithelial barrier and a…”
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Increased Escherichia coli-Induced Interleukin-23 Production by CD16+ Monocytes Correlates with Systemic Immune Activation in Untreated HIV-1-Infected Individuals by Manuzak, Jennifer A, Dillon, Stephanie M, Lee, Eric J, Dong, Zachary M, Hecht, Daniel K, Wilson, Cara C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Blood Myeloid Dendritic Cells from HIV-1-Infected Individuals Display a Proapoptotic Profile Characterized by Decreased Bcl-2 Levels and by Caspase-3+ Frequencies That Are Associated with Levels of Plasma Viremia and T Cell Activation in an Exploratory Study by DILLON, Stephanie M, FRIEDLANDER, Laura J, ROGERS, Lisa M, MEDITZ, Amie L, FOLKVORD, Joy M, CONNICK, Elizabeth, MCCARTER, Martin D, WILSON, Cara C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Low abundance of colonic butyrate-producing bacteria in HIV infection is associated with microbial translocation and immune activation by Dillon, Stephanie M, Kibbie, Jon, Lee, Eric J, Guo, Kejun, Santiago, Mario L, Austin, Gregory L, Gianella, Sara, Landay, Alan L, Donovan, Andrew M, Frank, Daniel N, McCarter, Martin D, Wilson, Cara C

“…OBJECTIVE:Gut microbial translocation is a major driving force behind chronic immune activation during HIV-1 infection. HIV-1-related intestinal dysbiosis,…”
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Butyrate directly decreases human gut lamina propria CD4 T cell function through histone deacetylase (HDAC) inhibition and GPR43 signaling by Kibbie, Jon J., Dillon, Stephanie M., Thompson, Tezha A., Purba, Christine M., McCarter, Martin D., Wilson, Cara C.

“…An important function of the gut microbiome is the fermentation of non-digestible dietary fibers into short chain fatty acids (SCFAs). The three primary SCFAs:…”
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Gut Bacteria Induce Granzyme B Expression in Human Colonic ILC3s In Vitro in an IL-15-Dependent Manner by Castleman, Moriah J, Dillon, Stephanie M, Thompson, Tezha A, Santiago, Mario L, McCarter, Martin D, Barker, Edward, Wilson, Cara C

“…Group 3 innate lymphoid cells (ILC3s) in the gut mucosa have long been thought to be noncytotoxic lymphocytes that are critical for homeostasis of intestinal…”
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What is the collective effect of aging and HIV on the gut microbiome? by Dillon, Stephanie M., Wilson, Cara C.

“…PURPOSE OF REVIEWAging and HIV share features of intestinal damage and alterations in the communities of enteric bacteria, termed dysbiosis. The purpose of…”
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Gut Innate Immunity and HIV Pathogenesis by Dillon, Stephanie M., Wilson, Cara C.

“…Purpose of Review In the gastro-intestinal tract, the complex network of multiple innate cell populations play critical roles not only as a first line of…”
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Microbiota-dependent indole production stimulates the development of collagen-induced arthritis in mice by Seymour, Brenda J, Trent, Brandon, Allen, Brendan E, Berlinberg, Adam J, Tangchittsumran, Jimmy, Jubair, Widian K, Chriswell, Meagan E, Liu, Sucai, Ornelas, Alfredo, Stahly, Andrew, Alexeev, Erica E, Dowdell, Alexander S, Sneed, Sunny L, Fechtner, Sabrina, Kofonow, Jennifer M, Robertson, Charles E, Dillon, Stephanie M, Wilson, Cara C, Anthony, Robert M, Frank, Daniel N, Colgan, Sean P, Kuhn, Kristine A

“…Altered tryptophan catabolism has been identified in inflammatory diseases like rheumatoid arthritis (RA) and spondyloarthritis (SpA), but the causal…”
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High-fat diet exacerbates SIV pathogenesis and accelerates disease progression by He, Tianyu, Xu, Cuiling, Krampe, Noah, Dillon, Stephanie M., Sette, Paola, Falwell, Elizabeth, Haret-Richter, George S., Butterfield, Tiffany, Dunsmore, Tammy L., McFadden, William M., Martin, Kathryn J., Policicchio, Benjamin B., Raehtz, Kevin D., Penn, Ellen P., Tracy, Russell P., Ribeiro, Ruy Miguel, Frank, Daniel N., Wilson, Cara C., Landay, Alan L., Apetrei, Cristian, Pandrea, Ivona

“…Copyright: © 2019. American Society for Clinical Investigation. Consuming a high-fat diet (HFD) is a risk factor for obesity and diabetes; both of these…”
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Altered Immunoglobulin Repertoire and Decreased IgA Somatic Hypermutation in the Gut during Chronic HIV-1 Infection by Jones, Sean T., Guo, Kejun, Cooper, Emily H., Dillon, Stephanie M., Wood, Cheyret, Nguyen, David H., Shen, Guannan, Barrett, Bradley S., Frank, Daniel N., Kroehl, Miranda, Janoff, Edward N., Kechris, Katerina, Wilson, Cara C., Santiago, Mario L.

“…Humoral immune perturbations contribute to pathogenic outcomes in persons with HIV-1 infection (PWH). Gut barrier dysfunction in PWH is associated with…”
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