Search Results - "Dillon, S.R"

The Murine Equivalent of the Heterozygous C104R TACI Mutation Impairs B Cell Function via Haploinsufficiency by Lee, J.J, Jabara, H.H, Garibyan, L, Rauter, I, Sannikova, T.Y, Dillon, S.R, Bram, R.J, Geha, R.S

“…Co-transfection of C76R with WT TACI did not exert a dominant negative effect on BAFF stimulated NF-κB driven luciferase reporter gene expression…”
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Interleukin (IL) 31 induces in cynomolgus monkeys a rapid and intense itch response that can be inhibited by an IL‐31 neutralizing antibody by Lewis, K.E., Holdren, M.S., Maurer, M.F., Underwood, S., Meengs, B., Julien, S.H., Byrnes‐Blake, K.A., Freeman, J.A., Bukowski, T.R., Wolf, A.C., Hamacher, N.B., Rixon, M.W., Dillon, S.R.

“…Background Overexpression or administration of interleukin 31 (IL‐31) has been shown to induce a profound itch response in mice and dogs. The chronic pruritus…”
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WCN23-0466 PHASE 1 STUDY IN HEALTHY ADULTS OF THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF ALPN-303, A DUAL BAFF/APRIL ANTAGONIST FOR THE TREATMENT OF AUTOIMMUNE GLOMERULONEPHRITIDES by Dillon, S.R., Davies, R., Lickliter, J.D., McLendon, K., Manjarrez, K.L., Smith, A., Lessig, M.C., Blanchfield, L., Sanderson, R.J., Chunyk, A.G., Enstrom, A., Blair, T., Hany Zayed, H.Z., LI, J., Peng, S.L.

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Atacicept (TACI-Ig) inhibits growth of primary myeloma cells in SCID-hu mice and in coculture with osteoclasts by Yaccoby, S, Pennisi, A, Li, X, Dillon, S.R, Zhan, F, Barlogie, B, Shaughnessy, Jr., J.D

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The receptor tyrosine kinase MerTK regulates dendritic cell production of BAFF by Gohlke, P. R., Williams, J. C., Vilen, B. J., Dillon, S. R., Tisch, R., Matsushima, G. K.

“…The MerTK receptor tyrosine kinase is an important negative regulator of dendritic cell function and is required to prevent B cell autoimmunity in vivo. It is…”
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