Search Results - "Dillon, S. R."

TACI-Ig Neutralizes Molecules Critical for B Cell Development and Autoimmune Disease: Impaired B Cell Maturation in Mice Lacking BLyS by Gross, Jane A, Dillon, Stacey R, Mudri, Sherri, Johnston, Janet, Littau, Alisa, Roque, Richard, Rixon, Mark, Schou, Ole, Foley, Kevin P, Haugen, Harald, McMillen, Susan, Waggie, Kim, Schreckhise, Randy W, Shoemaker, Kim, Vu, Tuyen, Moore, Margaret, Grossman, Angelika, Clegg, Chris H

“…BLyS and APRIL have similar but distinct biological roles, mediated through two known TNF receptor family members, TACI and BCMA. We show that mice treated…”
Get full text

A Soluble Class II Cytokine Receptor, IL-22RA2, is a Naturally Occurring IL-22 Antagonist by Xu, Wenfeng, Presnell, Scott R., Parrish-Novak, Julia, Kindsvogel, Wayne, Jaspers, Steve, Chen, Zhi, Dillon, Stacey R., Gao, Zeren, Gilbert, Teresa, Madden, Karen, Schlutsmeyer, Stacy, Yao, Lena, Whitmore, Theodore E., Chandrasekher, Yasmin, Grant, Francis J., Maurer, Mark, Jelinek, Laura, Storey, Harold, Brender, Ty, Hammond, Angie, Topouzis, Stavros, Clegg, Christopher H., Foster, Donald C.

“…IL-22 is an IL-10 homologue that binds to and signals through the class II cytokine receptor heterodimer IL-22RA1/CRF2-4. IL-22 is produced by T cells and…”
Get full text

V(D)J Recombinase Activity in a Subset of Germinal Center B Lymphocytes by Han, Shuhua, Dillon, Stacey R., Zheng, Biao, Shimoda, Michiko, Schlissel, Mark S., Kelsoe, Garnett

“…Reexpression of the V(D)J recombinase-activating genes RAG1 and RAG2 in germinal center B cells creates the potential for immunoglobulin gene rearrangement and…”
Get full text

TACI-Ig prevents the development of airway hyperresponsiveness in a murine model of asthma by Bilsborough, J., Chadwick, E., Mudri, S., Ye, X., Henderson Jr, W. R., Waggie, K., Hebb, L., Shin, J., Rixon, M., Gross, J. A., Dillon, S. R.

“…Summary Background Increased levels of serum IgE are associated with greater asthma prevalence and disease severity. IgE depletion using an anti‐IgE monoclonal…”
Get full text

Annexin V Binds to Positively Selected B Cells by Dillon, Stacey R, Constantinescu, Andrei, Schlissel, Mark S

“…Recombinant annexin V (rAnV) has been used in flow cytometry to identify cells undergoing apoptosis, based on its ability to bind to phosphatidylserine, a…”
Get full text

The receptor tyrosine kinase MerTK regulates dendritic cell production of BAFF by Gohlke, P. R., Williams, J. C., Vilen, B. J., Dillon, S. R., Tisch, R., Matsushima, G. K.

“…The MerTK receptor tyrosine kinase is an important negative regulator of dendritic cell function and is required to prevent B cell autoimmunity in vivo. It is…”
Get full text

Interleukin (IL) 31 induces in cynomolgus monkeys a rapid and intense itch response that can be inhibited by an IL‐31 neutralizing antibody by Lewis, K.E., Holdren, M.S., Maurer, M.F., Underwood, S., Meengs, B., Julien, S.H., Byrnes‐Blake, K.A., Freeman, J.A., Bukowski, T.R., Wolf, A.C., Hamacher, N.B., Rixon, M.W., Dillon, S.R.

“…Background Overexpression or administration of interleukin 31 (IL‐31) has been shown to induce a profound itch response in mice and dogs. The chronic pruritus…”
Get full text

Atacicept (TACI-Ig) inhibits growth of TACI(high) primary myeloma cells in SCID-hu mice and in coculture with osteoclasts by Yaccoby, S, Pennisi, A, Li, X, Dillon, S R, Zhan, F, Barlogie, B, Shaughnessy, Jr, J D

“…APRIL (a proliferation-inducing Ligand) and BLyS/BAFF (B-lymphocyte stimulator/B-cell-activating factor of the TNF (tumor necrosis factor) family have been…”
Get full text

Atacicept (TACI-Ig) inhibits growth of TACIhigh primary myeloma cells in SCID-hu mice and in coculture with osteoclasts by Yaccoby, S, Pennisi, A, Li, X, Dillon, S R, Zhan, F, Barlogie, B, Shaughnessy, J D

“…APRIL (a proliferation-inducing Ligand) and BLyS/BAFF (B-lymphocyte stimulator/B-cell-activating factor of the TNF (tumor necrosis factor) family have been…”
Get full text

IL-31 Expression by Inflammatory Cells is Preferentially Elevated in Atopic Dermatitis by NOBBE, Stephan, DZIUNYCZ, Piotr, MÜHLEISEN, Beda, BILSBOROUGH, Janine, DILLON, Stacey R, FRENCH, Lars E, HOFBAUER, Günther F. L

“…Interleukin-31 (IL-31) is a recently discovered cytokine expressed in many human tissues, and predominantly by activated CD4(+) T cells. IL-31 signals through…”
Get full text

TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease by Gross, Jane A, Johnston, Janet, Mudri, Sherri, Enselman, Rachel, Dillon, Stacey R, Madden, Karen, Xu, Wenfeng, Parrish-Novak, Julia, Foster, Don, Lofton-Day, Cathy, Moore, Margaret, Littau, Alisa, Grossman, Angelika, Haugen, Harald, Foley, Kevin, Blumberg, Hal, Harrison, Kim, Kindsvogel, Wayne, Clegg, Christopher H

“…B cells are important in the development of autoimmune disorders by mechanisms involving disregulated polyclonal B-cell activation, production of pathogenic…”
Get full text

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function by Foster, Don, Parrish-Novak, Julia, Dillon, Stacey R, Nelson, Andrew, Hammond, Angie, Sprecher, Cindy, Gross, Jane A, Johnston, Janet, Madden, Karen, Xu, Wenfeng, West, Jim, Schrader, Sara, Burkhead, Steve, Heipel, Mark, Brandt, Cameron, Kuijper, Joseph L, Kramer, Janet, Conklin, Darrell, Presnell, Scott R, Berry, Jon, Shiota, Faith, Bort, Susan, Hambly, Kevin, Mudri, Sherri, Clegg, Chris, Moore, Margaret, Grant, Francis J, Lofton-Day, Catherine, Gilbert, Teresa, Raymond, Fenella, Ching, Andrew, Yao, Lena, Smith, Deb, Webster, Philippa, Whitmore, Theodore, Maurer, Mark, Kaushansky, Kenneth, Holly, Rick D

“…Cytokines are important in the regulation of haematopoiesis and immune responses, and can influence lymphocyte development. Here we have identified a class I…”
Get full text

Annexin V Binds to Viable B Cells and Colocalizes with a Marker of Lipid Rafts upon B Cell Receptor Activation by Dillon, Stacey R, Mancini, Marie, Rosen, Antony, Schlissel, Mark S

“…Recombinant annexin V (rAnV) has been used to identify apoptotic cells based on its ability to bind phosphatidylserine (PS), a lipid normally restricted to the…”
Get full text

Improved hemodynamics shown by continuous monitoring of electrical impedance during external counterpulsation with the end-diastolic pneumatic boot and improved ambulatory EKG monitoring after 3 weeks of therapy by Dillon, R S

“…Six normal subjects and 12 patients with clinical angina and significant ST depressions during baseline ambulatory cardiac monitoring were given a single…”
Get more information

Wocko, a neurological mutant generated in a transgenic mouse pedigree by Crenshaw, EB, 3d, Ryan, A, Dillon, SR, Kalla, K, Rosenfeld, MG

“…Naturally occurring mutations involving the nervous system have provided virtually all of our current understanding of the genetic regulation of neural…”
Get full text

Successful treatment of osteomyelitis and soft tissue infections in ischemic diabetic legs by local antibiotic injections and the end-diastolic pneumatic compression boot by DILLON, R. S

“…Thirty-four legs at risk of amputation due to peripheral arterial insufficiency associated with ischemic necrosis, soft tissue infections, osteomyelitis, and…”
Get full text

Optimizing external cardiac-assist compressions in patients with atrial fibrillation by anticipating the next beat by Dillon, R S

“…Multiple empirical formulas predicting the next RR interval in centiseconds (CS) were tested on EKG strips obtained from 30 patients with atrial fibrillation…”
Get more information

Improved serum insulin profiles in diabetic individuals who massaged their insulin injection sites by Dillon, R S

“…Improved serum insulin profiles in diabetic individuals who massaged their insulin injection sites. R S Dillon Abstract Eight insulin-dependent diabetic…”
Get full text

Self-Respect: Moral, Emotional, Political by Dillon, Robin S.

“…Dillon argues that the emotional dimensions of certain dramas reveal self-respect to be more complexly structured than previous discussions of the concept have…”
Get full text

Role of cholinergic nervous system in healing neuropathic lesions: preliminary studies and prospective, double-blinded, placebo-controlled studies by Dillon, R S

“…The amplitudes of photo-electric-plethysmography (PPG) tracings were significantly increased by subcutaneous injections of methacholine (MC) and diminished by…”
Get more information