Search Results - "Dillon, John F."
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Guidelines on the management of abnormal liver blood tests
Published in Gut (01-01-2018)“…These updated guidelines on the management of abnormal liver blood tests have been commissioned by the Clinical Services and Standards Committee (CSSC) of the…”
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A systematic review and meta-analysis of community and primary-care-based hepatitis C testing and treatment services that employ direct acting antiviral drug treatments
Published in BMC health services research (28-10-2019)“…Direct Acting Antiviral (DAAs) drugs have a much lower burden of treatment and monitoring requirements than regimens containing interferon and ribavirin, and a…”
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Accuracy of Non-Invasive Imaging Techniques for the Diagnosis of MASH in Patients With MASLD: A Systematic Review
Published in Liver international (14-10-2024)“…Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing public health problem. The secondary stage in MASLD is steatohepatitis (MASH),…”
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Cost-Effectiveness of Treating Hepatitis C in Clients on Opioid Agonist Therapy in Community Pharmacies Compared to Primary Healthcare in Australia
Published in Journal of viral hepatitis (23-10-2024)“…Meeting the World Health Organisation 2030 target of treating 80% of people with hepatitis C virus (HCV) in Australia requires accessible testing and treatment…”
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Increased risk of chronic kidney disease and mortality in a cohort of people diagnosed with metabolic dysfunction associated steatotic liver disease with hepatic fibrosis
Published in PloS one (16-04-2024)“…Metabolic dysfunction associated steatotic liver disease (MASLD) increases the risk of incident chronic kidney disease (CKD). However, the relative risk of CKD…”
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Drug‐Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles
Published in Clinical pharmacology and therapeutics (01-07-2019)“…Some patients prescribed flucloxacillin (~ 0.01%) develop drug‐induced liver injury (DILI). HLA‐B*57:01 is an established genetic risk factor for…”
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Toward a more complete understanding of the association between a hepatitis C sustained viral response and cause‐specific outcomes
Published in Hepatology (Baltimore, Md.) (01-08-2015)“…Sustained viral response (SVR) is the optimal outcome of hepatitis C virus (HCV) therapy, yet more detailed data are required to confirm its clinical value…”
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Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2)
Published in Cellular and molecular gastroenterology and hepatology (01-01-2018)“…Background & Aims Nonalcoholic steatohepatitis (NASH) is associated with oxidative stress. We surmised that pharmacologic activation of NF-E2 p45-related…”
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Mixed-methods evaluation of point-of-care hepatitis C virus RNA testing in a Scottish prison
Published in BMJ open (10-04-2023)“…ObjectivesHepatitis C virus (HCV) poses a global public health threat. Prisons are a focus of prevention efforts due to high infection burdens. Expedition of…”
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Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis
Published in Free radical biology & medicine (15-01-2010)“…Nonalcoholic steatohepatitis (NASH) arises from nonalcoholic fatty liver disease (NAFLD) as a consequence of oxidative stress. Herein we report that the…”
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Thrombocytosis and abnormal liver enzymes: A trigger for investigation of underlying malignancy
Published in PloS one (28-04-2022)“…Thrombocytosis is often an incidental finding in primary care with a range of causes. Despite evidence of a strong association between thrombocytosis and…”
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Optimal ALT threshold for the automated diagnosis of MASLD: A population-based study using iLFT
Published in Annals of hepatology (01-03-2024)“…Early diagnosis of metabolic dysfunction-associated steatotic liver disease (MASLD), especially with advanced fibrosis, is crucial due to the increased risk of…”
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Transformation of identity in substance use as a pathway to recovery and the potential of treatment for hepatitis C: a systematic review protocol
Published in BMJ open (07-02-2022)“…IntroductionHepatitis C virus (HCV) is a strongly stigmatised disease as it is framed within the context of injecting substance use. HCV provides the identity…”
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Mortality in hepatitis C patients who achieve a sustained viral response compared to the general population
Published in Journal of hepatology (01-01-2017)“…Graphical abstract…”
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Laying the foundations for hepatitis C elimination: evaluating the development and contribution of community care pathways to diagnostic efforts
Published in BMC public health (07-01-2023)“…Hepatitis C Virus (HCV) is a public health threat which contributes substantially to the global burden of liver disease. There is much debate about effective…”
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Intelligent Liver Function Testing (iLFT): An Intelligent Laboratory Approach to Identifying Chronic Liver Disease
Published in Diagnostics (Basel) (01-05-2024)“…The intelligent Liver Function Testing (iLFT) pathway is a novel, algorithm-based system which provides automated laboratory investigations and clinical…”
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Future destinations and social inclusion scoping review: how people cured of hepatitis C (HCV) using direct- acting antiviral drugs progress in a new HCV-free world
Published in Substance abuse treatment, prevention and policy (08-06-2022)“…There has been a paradigm shift in the treatment of Hepatitis C (HCV) from the interferon-era to direct-acting antiviral (DAA) drugs. Cure of HCV for the key…”
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Enhanced liver fibrosis (ELF) score predicts hepatic decompensation and mortality
Published in JHEP reports (01-06-2024)“…In community pathways for detection of liver disease the most common reason for referral is fibrosis assessment. We investigated the impact of adding the…”
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A multistakeholder approach to innovations in NAFLD care
Published in Communications medicine (03-01-2023)“…Non-alcoholic fatty liver disease (NAFLD) is highly prevalent globally and requires multidisciplinary care. Here, we report key findings of a NAFLD care…”
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Long-term risk factors for developing Barrett’s oesophagus in patients with gastro-oesophageal reflux disease: a longitudinal cohort study
Published in BMJ open gastroenterology (22-03-2024)“…Background and aimsSeveral characteristics are known to affect the risk of Barrett’s oesophagus (BO) in the general population, with symptomatic…”
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