Search Results - "Dillon, John"
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The Micro-Elimination Approach to Eliminating Hepatitis C: Strategic and Operational Considerations
Published in Seminars in liver disease (01-08-2018)“…The introduction of efficacious new hepatitis C virus (HCV) treatments galvanized the World Health Organization to define ambitious targets for eliminating HCV…”
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Guidelines on the management of abnormal liver blood tests
Published in Gut (01-01-2018)“…These updated guidelines on the management of abnormal liver blood tests have been commissioned by the Clinical Services and Standards Committee (CSSC) of the…”
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3
Gamma‐Glutamyl Transferase (γ‐GT) – an old dog with new tricks?
Published in Liver international (01-01-2022)“…Gamma‐Glutamyl Transferase (γGT) is a key transferase involved in the transpeptidation of functional gamma‐glutamyl groups to various receptor moieties. It…”
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DOT-C: A cluster randomised feasibility trial evaluating directly observed anti-HCV therapy in a population receiving opioid substitute therapy from community pharmacy
Published in The International journal of drug policy (01-09-2017)“…Direct-acting antiviral therapy (DAAs) for hepatitis C infection (HCV) have a much smaller burden of treatment than interferon-based regimes, require less…”
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Effectiveness of the use of implementation intentions on reduction of substance use: A meta-analysis
Published in Drug and alcohol dependence (01-09-2020)“…•Small significant effect of implementation intentions on reducing alcohol use, g = 0.31 (95 % CI: 0.21, 0.42), p < .001.•Small significant effect of…”
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Accuracy of Non-Invasive Imaging Techniques for the Diagnosis of MASH in Patients With MASLD: A Systematic Review
Published in Liver international (14-10-2024)“…Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing public health problem. The secondary stage in MASLD is steatohepatitis (MASH),…”
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Cost-Effectiveness of Treating Hepatitis C in Clients on Opioid Agonist Therapy in Community Pharmacies Compared to Primary Healthcare in Australia
Published in Journal of viral hepatitis (23-10-2024)“…Meeting the World Health Organisation 2030 target of treating 80% of people with hepatitis C virus (HCV) in Australia requires accessible testing and treatment…”
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A systematic review and meta-analysis of community and primary-care-based hepatitis C testing and treatment services that employ direct acting antiviral drug treatments
Published in BMC health services research (28-10-2019)“…Direct Acting Antiviral (DAAs) drugs have a much lower burden of treatment and monitoring requirements than regimens containing interferon and ribavirin, and a…”
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Nonalcoholic steatohepatitis and mechanisms by which it is ameliorated by activation of the CNC-bZIP transcription factor Nrf2
Published in Free radical biology & medicine (01-08-2022)“…Non-alcoholic steatohepatitis (NASH) represents a global health concern. It is characterised by fatty liver, hepatocyte cell death and inflammation, which are…”
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Transformation of identity in substance use as a pathway to recovery and the potential of treatment for hepatitis C: a systematic review
Published in Addiction (Abingdon, England) (01-03-2023)“…Background and aim People who inject drugs are at high risk of contracting hepatitis C (HCV). The introduction of direct acting antiviral (DAA) drugs to treat…”
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Hepatitis C virus treatment for prevention among people who inject drugs: Modeling treatment scale‐up in the age of direct‐acting antivirals
Published in Hepatology (Baltimore, Md.) (01-11-2013)“…Substantial reductions in hepatitis C virus (HCV) prevalence among people who inject drugs (PWID) cannot be achieved by harm reduction interventions such as…”
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Increased risk of chronic kidney disease and mortality in a cohort of people diagnosed with metabolic dysfunction associated steatotic liver disease with hepatic fibrosis
Published in PloS one (16-04-2024)“…Metabolic dysfunction associated steatotic liver disease (MASLD) increases the risk of incident chronic kidney disease (CKD). However, the relative risk of CKD…”
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Reactive Oxygen Species and Oxidative Stress in the Pathogenesis of MAFLD
Published in Journal of clinical and translational hepatology (28-10-2022)“…The pathogenesis of metabolic-associated fatty liver disease (MAFLD) is complex and thought to be dependent on multiple parallel hits on a background of…”
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Thrombocytosis and abnormal liver enzymes: A trigger for investigation of underlying malignancy
Published in PloS one (28-04-2022)“…Thrombocytosis is often an incidental finding in primary care with a range of causes. Despite evidence of a strong association between thrombocytosis and…”
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Systematic review: the role of frailty in advanced chronic liver disease
Published in Alimentary pharmacology & therapeutics (01-02-2023)“…Frailty is a known predictor of outcome and mortality in patients undergoing liver transplantation. However, most patients remain unsuitable transplant…”
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Hepatitis C reinfection after successful antiviral treatment among people who inject drugs: A meta-analysis
Published in Journal of hepatology (01-04-2020)“…HCV reinfection following successful treatment can compromise treatment outcomes. This systematic review assessed the rate of HCV reinfection following…”
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Determining the role for uric acid in non-alcoholic steatohepatitis development and the utility of urate metabolites in diagnosis: An opinion review
Published in World journal of gastroenterology : WJG (21-04-2020)“…There has long been a recognised association between non-alcoholic fatty liver disease (NAFLD) and the composite aspects of the metabolic syndrome. Part of…”
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High response and re‐infection rates among people who inject drugs treated for hepatitis C in a community needle and syringe programme
Published in Journal of viral hepatitis (01-05-2019)“…Summary To achieve WHO hepatitis C virus (HCV) elimination targets by 2030, mathematical models suggest there needs to be significant scale‐up of treatment…”
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MAIT cells are activated during human viral infections
Published in Nature communications (23-06-2016)“…Mucosal-associated invariant T (MAIT) cells are abundant in humans and recognize bacterial ligands. Here, we demonstrate that MAIT cells are also activated…”
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The effect of introducing point-of-care or dried blood spot analysis on the uptake of hepatitis C virus testing in high-risk populations: A systematic review of the literature
Published in The International journal of drug policy (01-11-2015)“…Highlights • New testing methods for hepatitis C virus are needed to target high risk populations. • Dried blood spots and point of care testing both aim to…”
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