Search Results - "Dillingham, Elwood O."

Design and Synthesis of Piperidine-3-carboxamides as Human Platelet Aggregation Inhibitors by Zheng, Xiaozhang, Salgia, Somna R, Thompson, Walter B, Dillingham, Elwood O, Bond, Stephen.E, Feng, Zixia, Prasad, K. Ram, Gollamudi, Ram

“…A detailed structure-activity analysis was carried out using eight 1-alkyl(aralkyl)nipecotamides (type 5), 33 bis-nipecotamidoalkanes and aralkanes (type 6),…”
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Antithrombotic nipecotamide increases cyclic AMP levels and inhibits protein phosphorylation in human platelets by Handa, R K, Dillingham, E O, Gollamudi, R

“…alpha,alpha'-bis[3-(N,N-diethylcarbamoyl)piperidino]-p-xylene dihydrobromide (A-1), a typical antithrombotic nipecotamide, elevated the levels of cyclic…”
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Molecular determinants of the platelet aggregation inhibitory activity of carbamoylpiperidines by Feng, Zixia, Gollamudi, Ramachander, Dillingham, Elwood O, Bond, Stephen E, Lyman, Beverly A, Purcell, William P, Hill, Robert J, Korfmacher, Walter A

“…A series of alpha,alpha'-bis[3-(N,N-dialkylcarbamoyl)piperidino]-p- xylenes were synthesized and tested for their inhibitory activity on ADP-induced…”
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Design and Synthesis of Piperidine-3-carboxamides as Human Platelet Aggregation Inhibitors [Erratum to document cited in CA122:95850] by Zheng, Xiaozhang, Salgia, Somna R, Thompson, Walter B, Dillingham, Elwood O, Bond, Stephen E, Feng, Zixia, Prasad, K. Ram, Gollamudi, Ram

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Relationships between chemical structure and inhibition of epinephrine-induced human blood platelet aggregation by Petrusewicz, J, Lasslo, A, Carter-Burks, G, Gollamudi, R, Dillingham, E O, Bond, S E

“…The effect of structural features in a series of carbamoylpiperidine and nipecotoylpiperazine congeners on epinephrine-induced aggregation of human blood…”
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Cytosolic ionized calcium in human platelets: the influence of collagen and a novel antiplatelet agent by Gollamudi, R, Dillingham, E O, Bond, S E, Lyman, B A

“…Two phases of calcium mobilization were observed when aequorin-loaded human platelets, suspended in a nominally calcium-free medium containing 0.1 mM EGTA,…”
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Preliminary in vivo studies on the platelet aggregation inhibitory activity of alpha, alpha'-bis[3-(N,N-diethylcarbamoyl)piperidino]-p-xylene dihydrobromide in beagle dogs by Lawrence, W H, Gollamudi, R, Dillingham, E O, Carter-Burks, G, Tisdelle, P A, Lasslo, A

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Relationships between chemical structure and inhibition of ADP-stimulated human thrombocyte release of serotonin and platelet factor 4 by Dillingham, E O, Lasslo, A, Carter-Burks, G, Bond, S E, Gollamudi, R

“…The inhibitory potencies of carbamoylpiperidinoalkane and N-alkylnipecotoylpiperazine derivatives on ADP-stimulated human blood platelet aggregation, serotonin…”
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Effects of novel aggregation inhibitors on serotonin uptake by human blood platelets by Lasslo, A, Dillingham, E O, Gollamudi, R, Carter-Burks, G

“…Novel aggregation inhibitors blocked serotonin uptake by human blood platelets in concentrations ranging from 0.7 +/- 0.1 microM to 237.5 +/- 35.7 microM; a…”
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The influence of urea and cell-surface protein on the behavior of nontumorigenic and chemically transformed cells by Phelps, A W, Dillingham, E O, Autian, J

“…Alterations in cell-cell interactions induced by urea and urea-isolated cell-surface protein (CSP) were examined using the nontumorigenic mouse fibroblast…”
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Antiplatelet effects of r, s-( meso)- α, α′- bis[3-( n , n-diethylcarbamoyl) piperidino]- p-xylene ex vivo in the dog and in vivo in the mouse by Han, Guozhu, Bannerman, Dana, Handa, Raj K., Dillingham, Elwood O., Lawrence, W.Homer, Gollamudi, Ram

“…1. 1. The nipecotamide α,α′-bis[3-(N,N-diethylcarbamoyl)piperidino]-p-xylene (A-1) is a platelet aggregation inhibitor. The meso diastereomer A-1c is superior…”
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Synergistic antiplatelet effects of a nipecotamide A-1C and low dose aspirin by Han, G, Bond, S E, Lawrence, W H, Dillingham, E O, Zheng, X, Gollamudi, R

“…1. The effects of an antithrombotic nipecotamide, A-1, and aspirin were examined separately and in combination, on human platelet aggregation in vitro and on…”
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