Search Results - "Dillen, L"

High-Resolution Mass Spectrometry Quantification: Impact of Differences in Data Processing of Centroid and Continuum Data by Vereyken, L., Dillen, L., Vreeken, R. J., Cuyckens, F.

“…High-resolution mass spectrometry (HRMS) in full scan mode acquires all ions present in the sample of interest offering a lot of qualitative information. This,…”
Get full text

2′-Deoxy-2′-spirocyclopropylcytidine Revisited: A New and Selective Inhibitor of the Hepatitis C Virus NS5B Polymerase by Jonckers, Tim H. M, Lin, Tse-I, Buyck, Christophe, Lachau-Durand, Sophie, Vandyck, Koen, Van Hoof, Steven, Vandekerckhove, Leen A. M, Hu, Lili, Berke, Jan Martin, Vijgen, Leen, Dillen, Lieve L. A, Cummings, Maxwell D, de Kock, Herman, Nilsson, Magnus, Sund, Christian, Rydegård, Christina, Samuelsson, Bertil, Rosenquist, Åsa, Fanning, Gregory, Van Emelen, Kristof, Simmen, Kenneth, Raboisson, Pierre

“…The current therapy for hepatitis C virus (HCV) infection has limited efficacy, in particular against the genotype 1 virus, and a range of side effects. In…”
Get full text

Inhibition of all-TRANS-retinoic acid metabolism by R116010 induces antitumour activity by VAN HEUSDEN, J, VAN GINCKEL, R, DILLEN, L, VAN HOVE, C, WILLEMSENS, G, JANICOT, M, WOUTERS, W, BRUWIERE, H, MOELANS, P, JANSSEN, B, FLOREN, W, VAN DER LEEDE, B. J, VAN DUN, J, SANZ, G, VENET, M

“…All-trans-retinoic acid is a potent inhibitor of cell proliferation and inducer of differentiation. However, the clinical use of all-trans-retinoic acid in the…”
Get full text

Use of a Classification System to Guide Nonsurgical Management of a Patient With Chronic Low Back Pain by Maluf, K S, Sahrmann, S A, Van Dillen, L R

“…This case report describes the use of a classification system in the evaluation of a patient with chronic low back pain (LBP) and illustrates how this system…”
Get full text

Novel Temporary Treatment for a Severe Case of Syndrome of Trephined by Dillen, William L., Pittman, Thomas A., Grupke, Stephen L.

“…Syndrome of the trephined is a unique neurosurgical condition that is seen in patients that have undergone craniectomy. While the symptoms of the condition…”
Get full text

Older parents’ experiences following a serious illness trajectory of an adult child: A review of the literature and recommendations for future research by Van Humbeeck, L, Piers, R, Dillen, L, Verhaeghe, S, Van Den Noortgate, N

Get full text

Novel approach to the treatment of a cerebral abscess using the Apollo vibration/suction device by Dillen, William L., van Horne, Craig G., Fraser, Justin F.

“…•Brief Review of intracerebral abscesses and current surgical treatment options.•Presentation of First reported use of the Apollo for intracerebral abscess…”
Get full text

Surfer’s myelopathy: A rare presentation in a teenage gymnast and review of the literature by Dillen, William L., Hendricks, Benjamin K., Mannas, Jonathan P., Wheeler, Greg R.

“…•A review of the literature pertaining to Surfer’s Myelopathy.•Presentation of the first reported case of Surfer’s Myelopathy in a gymnast.•Delayed…”
Get full text

Predictors of re-operation in the setting of non-acute subdural hematomas: A 12-year single center retrospective study by Maher Hulou, M., McLouth, Christopher J., Hayden, Christopher S., Sheldrake, Amy K., Parekh, Mansi, Dillen, William L., Wheeler, Greg R., Fraser, Justin F.

“…•Operative technique, thrombocytopenia, and presence of postoperative acute blood are significant predictors of reoperation.•Postoperative residual hematoma…”
Get full text

Effect of active limb movements on symptoms in patients with low back pain by Van Dillen, L R, Sahrmann, S A, Norton, B J, Caldwell, C A, Fleming, D, McDonnell, M K, Bloom, N J

“…A descriptive, correlational study of patients with mechanical low back pain (LBP). To assess the effect of active limb movements on symptoms in patients with…”
Get full text

Synthesis and Biological Evaluation of 1,2,4-Triazinylphenylalkylthiazolecarboxylic Acid Esters as Cytokine-Inhibiting Antedrugs with Strong Bronchodilating Effects in an Animal Model of Asthma by Freyne, Eddy J, Lacrampe, Jean F, Deroose, Frederik, Boeckx, Gustaaf M, Willems, Marc, Embrechts, Werner, Coesemans, Erwin, Willems, Johan J, Fortin, Jerome M, Ligney, Yannick, Dillen, Lieve L, Cools, Willy F, Goossens, Jan, Corens, David, De Groot, Alex, Van Wauwe, Jean P

“…The influx of leukocytes (eosinophils, lymphocytes, and monocytes) into the airways and their production of proinflammatory cytokines contribute to the…”
Get full text

Antimicrobial peptides from Amaranthus caudatus seeds with sequence homology to the cysteine/glycine-rich domain of chitin-binding proteins by Broekaert, Willem F, Marien, Wim, Terras, Franky R. G, De Bolle, Miguel F. C, Proost, Paul, Van Damme, Jozef, Dillen, Lieve, Claeys, Magda, Rees, Sarah B

“…Two antimicrobial peptides (Ac-AMP1 and Ac-AMP2) were isolated from seeds of amaranth (Amaranthus caudatus), and their physicochemical and biological…”
Get full text

All-trans-retinoic acid metabolites significantly inhibit the proliferation of MCF-7 human breast cancer cells in vitro by VAN HEUSDEN, J, WOUTERS, W, RAMAEKER, F, KREKELS, M, DILLEN, L, BORGERS, M, SMETS, G

“…All-trans-retinoic acid (ATRA) is well known to inhibit the proliferation of human breast cancer cells. Much less is known about the antiproliferative activity…”
Get full text

Reliability of Physical Examination Items Used for Classification of Patients With Low Back Pain by Van Dillen, L R, Sahrmann, S A, Norton, B J, Caldwell, C A, Fleming, D A, McDonnell, M K, Woolsey, N B

“…The purpose of this study was to examine the interrater reliability of measurements obtained by examiners administering tests proposed to be important for…”
Get full text

The antiproliferative activity of all-trans-retinoic acid catabolites and isomers is differentially modulated by liarozole-fumarate in MCF-7 human breast cancer cells by VAN HEUSDEN, J, WOUTERS, W, RAMAEKERS, F. C. S, KREKELS, M. D. W. G, DILLEN, L, BORGERS, M, SMETS, G

“…The clinical use of all-trans-retinoic acid (ATRA) in the treatment of cancer is significantly hampered by the prompt emergence of resistance, believed to be…”
Get full text

Posttranslational processing of proenkephalins and chromogranins/secretogranins by Dillen, L, Miserez, B, Claeys, M, Aunis, D, De Potter, W

“…Posttranslational processing of peptide-precursors is nowadays believed to play an important role in the functioning of neurons and endocrine cells. Both…”
Get more information

A comprehensive study of the genetic impact of rare variants in SORL1 in European early-onset Alzheimer’s disease by Verheijen, Jan, Van den Bossche, Tobi, van der Zee, Julie, Engelborghs, Sebastiaan, Sanchez-Valle, Raquel, Lladó, Albert, Graff, Caroline, Thonberg, Håkan, Pastor, Pau, Ortega-Cubero, Sara, Pastor, Maria A., Benussi, Luisa, Ghidoni, Roberta, Binetti, Giuliano, Clarimon, Jordi, Lleó, Alberto, Fortea, Juan, de Mendonça, Alexandre, da Rocha Martins, Madalena Cristina, Grau-Rivera, Oriol, Gelpi, Ellen, Bettens, Karolien, Mateiu, Ligia, Dillen, Lubina, Cras, Patrick, De Deyn, Peter P., Van Broeckhoven, Christine, Sleegers, Kristel

“…© The Author(s) 2016. This article is published with open access at Springerlink.com. This article is distributed under the terms of the Creative Commons…”
Get full text

Plasma phosphorylated TDP-43 levels are elevated in patients with frontotemporal dementia carrying a C9orf72 repeat expansion or a GRN mutation by Suárez-Calvet, Marc, Dols-Icardo, Oriol, Lladó, Albert, Sánchez-Valle, Raquel, Hernández, Isabel, Amer, Guillermo, Antón-Aguirre, Sofía, Alcolea, Daniel, Fortea, Juan, Ferrer, Isidre, van der Zee, Julie, Dillen, Lubina, Van Broeckhoven, Christine, Molinuevo, José Luís, Blesa, Rafael, Clarimón, Jordi, Lleó, Alberto

“…Objectives About a half of patients with frontotemporal dementia (FTD) has deposition of phosphorylated TDP-43 protein (pTDP-43) in the brain. We studied…”
Get full text

Bioanalysis for plasma protein binding studies in drug discovery and drug development: views and recommendations of the European Bioanalysis Forum by Buscher, Brigitte, Laakso, Sirpa, Mascher, Hermann, Pusecker, Klaus, Doig, Mira, Dillen, Lieve, Wagner-Redeker, Winfried, Pfeifer, Thomas, Delrat, Pascal, Timmerman, Philip

“…Plasma protein binding (PPB) is an important parameter for a drug's efficacy and safety that needs to be investigated during each drug-development program…”
Get full text

Study of the enzymatic degradation of vasostatin I and II and their precursor chromogranin A by dipeptidyl peptidase IV using high-performance liquid chromatography/electrospray mass spectrometry by Zhang, X. Y., De Meester, I., Lambeir, A.-M., Dillen, L., Van Dongen, W., Esmans, E. L., Haemers, A., Scharpé, S., Claeys, M.

“…The interaction of dipeptidyl peptidase IV with structurally related proteins differing in chain length, namely vasostatin I and II and their precursor protein…”
Get full text