Search Results - "Dillehay, Dirck L."

Sphingolipids in food and the emerging importance of sphingolipids to nutrition by Vesper, H, Schmelz, E M, Nikolova-Karakashian, M N, Dillehay, D L, Lynch, D V, Merrill, Jr, A H

“…Eukaryotic organisms as well as some prokaryotes and viruses contain sphingolipids, which are defined by a common structural feature, i.e. , a "sphingoid base"…”
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Sphingomyelin in the suppression of colon tumors: prevention versus intervention by Lemonnier, Lori A, Dillehay, Dirck L, Vespremi, Michael J, Abrams, Judith, Brody, Ernest, Schmelz, Eva M

“…Intestinal cells are regularly exposed to sphingolipid metabolites, i.e., ceramide and sphingoid bases, after hydrolysis of complex sphingolipids from the…”
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Colonic cell proliferation and aberrant crypt foci formation are inhibited by dairy glycosphingolipids in 1, 2-dimethylhydrazine-treated CF1 mice by Schmelz, E M, Sullards, M C, Dillehay, D L, Merrill, Jr, A H

“…Dietary sphingomyelin (SM) inhibits early stages of colon cancer (appearance of aberrant crypt foci, ACF) and decreases the proportion of adenocarcinomas vs…”
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Regulation of Hepatic Cytochrome P450 Expression in Mice with Intestinal or Systemic Infections of Citrobacter rodentium by CHALUVADI, Madhusudana R, KINLOCH, Ryan D, NYAGODE, Beatrice A, RICHARDSON, Terrilyn A, RAYNOR, Malik J, SHERMAN, Melanie, ANTONOVIC, Leposava, STROBEL, Henry W, DILLEHAY, Dirck L, MORGAN, Edward T

“…We reported previously that infection of C3H/HeOuJ (HeOu) mice with the murine intestinal pathogen Citrobacter rodentium caused a selective modulation of…”
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Pathogenic virus-specific T cells cause disease during treatment with the calcineurin inhibitor FK506: implications for transplantation by Araki, Koichi, Gangappa, Shivaprakash, Dillehay, Dirck L, Rouse, Barry T, Larsen, Christian P, Ahmed, Rafi

“…Recently, several cases of fatal lymphocytic choriomeningitis virus (LCMV) infection occurred in transplant recipients being treated with the immunosuppressive…”
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Enigmol: a novel sphingolipid analogue with anticancer activity against cancer cell lines and in vivo models for intestinal and prostate cancer by Symolon, Holly, Bushnev, Anatoliy, Peng, Qiong, Ramaraju, Harsha, Mays, Suzanne G, Allegood, Jeremy C, Pruett, Sarah T, Sullards, M Cameron, Dillehay, Dirck L, Liotta, Dennis C, Merrill, Jr, Alfred H

“…Sphingoid bases are cytotoxic for many cancer cell lines and are thought to contribute to suppression of intestinal tumorigenesis in vivo by ingested…”
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PIKE-A is required for prolactin-mediated STAT5a activation in mammary gland development by Chan, Chi-Bun, Liu, Xia, Ensslin, Michael A, Dillehay, Dirck L, Ormandy, Christopher J, Sohn, Philip, Serra, Rosa, Ye, Keqiang

“…PI 3‐kinase enhancer A (PIKE‐A) is critical for the activation of Akt signalling, and has an essential function in promoting cancer cell survival. However, its…”
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Importance of sphingolipids and inhibitors of sphingolipid metabolism as components of animal diets by Merrill, Jr, A H, Schmelz, E M, Wang, E, Dillehay, D L, Rice, L G, Meredith, F, Riley, R T

“…Sphingolipids are highly bioactive compounds that participate in the regulation of cell growth, differentiation, diverse cell functions, and apoptosis. They…”
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Regulation of Vascular Endothelial Growth Factor Production and Angiogenesis by the Cytoplasmic Tail of Tissue Factor by Abe, Keisuke, Shoji, Mamoru, Chen, Jiang, Bierhaus, Angelika, Danave, Indrani, Micko, Cornelia, Casper, Katherine, Dillehay, Dirck L., Nawroth, Peter P., Rickles, Frederick R.

“…Tissue factor (TF), a transmembrane receptor for coagulation factor VII/VIIa, is aberrantly expressed in human cancers. We demonstrated a significant…”
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Modulation of intracellular β-catenin localization and intestinal tumorigenesis in vivo and in vitro by sphingolipids by SCHMELZ, Eva M, ROBERTS, Paul C, KUSTIN, Elizabeth M, LEMONNIER, Lori A, SULLARDS, M. Cameron, DILLEHAY, Dirck L, MERRILL, Alfred H

“…Sphingolipid consumption suppresses colon carcinogenesis, but the specific genetic defect(s) that can be bypassed by these dietary components are not known…”
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Ectopical expression of human MUC18 increases metastasis of human prostate cancer cells by Wu, Guang-Jer, Peng, Qiong, Fu, Pingping, Wang, Shur-Wern, Chiang, Cheng-Feng, Dillehay, Dirck L., Wu, Mei-Whey H.

“…MUC18, a cell adhesion molecule (CAM), has been reported to be a diagnostic marker for the early detection of the metastatic potential of prostate cancers as…”
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Maternal Germ-Line Transmission of Mutant mtDNAs from Embryonic Stem Cell-Derived Chimeric Mice by Sligh, J E, Levy, S E, Waymire, K G, Allard, P, Dillehay, D L, Nusinowitz, S, Heckenlively, J R, MacGregor, G R, Wallace, D C

“…We report a method for introducing mtDNA mutations into the mouse female germ line by means of embryonic stem (ES) cell cybrids. Mitochondria were recovered…”
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Overexpression of aromatase leads to development of testicular Leydig cell tumors: An in vivo model for hormone-mediated testicular cancer by FOWLER, K. A, GILL, K, KIRMA, N, DILLEHAY, D. L, RAJESHWAR RAO TEKMAL

“…Despite recent advances in diagnosis and treatment of testicular cancer, its causes remain unknown. The most common conditions known to be associated with…”
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Sphingoid bases and de novo ceramide synthesis: enzymes involved, pharmacology and mechanisms of action by Menaldino, David S, Bushnev, Anatoliy, Sun, Aiming, Liotta, Dennis C, Symolon, Holly, Desai, Kena, Dillehay, Dirck L, Peng, Qiong, Wang, Elaine, Allegood, Jeremy, Trotman-Pruett, Sarah, Sullards, M.Cameron, Merrill, Alfred H

“…The sphingoid base backbones of sphingolipids (sphingosines, sphinganines, 4-hydroxysphinganines and others) are highly bioactive species directly and—in most…”
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Sphingomyelin consumption suppresses aberrant colonic crypt foci and increases the proportion of adenomas versus adenocarcinomas in CF1 mice treated with 1,2-dimethylhydrazine : Implications for dietary sphingolipids and colon carcinogenesis by SCHMELZ, E. M, DILLEHAY, D. L, WEBB, S. K, REITER, A, ADAMS, J, MERRILL, A. H

“…Sphingolipids are hydrolyzed in the gastrointestinal tract to ceramide, sphingosine, and other metabolites that can modulate cell growth, differentiation, and…”
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A Single Amino Acid Change in the Hemagglutinin Protein of Measles Virus Determines Its Ability To Bind CD46 and Reveals Another Receptor on Marmoset B Cells by Hsu, E C, Sarangi, F, Iorio, C, Sidhu, M S, Udem, S A, Dillehay, D L, Xu, W, Rota, P A, Bellini, W J, Richardson, C D

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Ischemia-reperfusion increases transfection efficiency of intracoronary adenovirus type 5 in pig heart in situ by Shi, Weiwei, Schmarkey, L Susan, Jiang, Rong, Bone, C Collin, Condit, Marah E, Dillehay, Dirck L, Engler, Robert L, Rubanyi, Gabor M, Vinten-Johansen, Jakob

“…Efficiency of intracoronary (IC) adenoviral vector transfection is impaired by the vascular endothelium. Ischemia and substances that increase vascular…”
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Dietary sphingomyelin inhibits 1,2-dimethylhydrazine-induced colon cancer in CF1 mice by Dillehay, D L, Webb, S K, Schmelz, E M, Merrill, Jr, A H

“…Sphingolipids are in all eukaryotic cells and modulate cell growth, differentiation, and transformation; however, little is known about the physiological…”
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Uptake and metabolism of sphingolipids in isolated intestinal loops of mice by Schmelz, E M, Crall, K J, Larocque, R, Dillehay, D L, Merrill, Jr, A H

“…Sphingolipids are found in all eukaryotic organisms. However, little is known about the digestion, uptake and subsequent metabolism of these constituents of…”
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Overexpression of int-5/aromatase in mammary glands of transgenic mice results in the induction of hyperplasia and nuclear abnormalities by RAJESHWAR RAO TEKMAL, RAMACHANDRA, N, GUBBA, S, DURGAM, V. R, MANTIONE, J, TODA, K, SHIZUTA, Y, DILLEHAY, D. L

“…Our recent studies have shown that the cellular gene at the mouse mammary tumor virus integration site in the int-5 locus is aromatase. To study the role of…”
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