Search Results - "Dillard, Miriam"

The Prox1-Vegfr3 feedback loop maintains the identity and the number of lymphatic endothelial cell progenitors by Srinivasan, R Sathish, Escobedo, Noelia, Yang, Ying, Interiano, Ashley, Dillard, Miriam E, Finkelstein, David, Mukatira, Suraj, Gil, Hyea Jin, Nurmi, Harri, Alitalo, Kari, Oliver, Guillermo

“…The mammalian lymphatic vasculature is important for returning fluids from the extracellular tissue milieu back to the blood circulation. We showed previously…”
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Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature by Srinivasan, R Sathish, Dillard, Miriam E, Lagutin, Oleg V, Lin, Fu-Jung, Tsai, Sophia, Tsai, Ming-Jer, Samokhvalov, Igor M, Oliver, Guillermo

“…The origin of the mammalian lymphatic vasculature has been debated for more than 100 years. Whether lymphatic endothelial cells have a single or dual, venous…”
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Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity by Johnson, Nicole C, Dillard, Miriam E, Baluk, Peter, McDonald, Donald M, Harvey, Natasha L, Frase, Sharon L, Oliver, Guillermo

“…The activity of the homeobox gene Prox1 is necessary and sufficient for venous blood endothelial cells (BECs) to acquire a lymphatic endothelial cell (LEC)…”
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Cytoneme delivery of Sonic Hedgehog from ligand-producing cells requires Myosin 10 and a Dispatched-BOC/CDON co-receptor complex by Hall, Eric T, Dillard, Miriam E, Stewart, Daniel P, Zhang, Yan, Wagner, Ben, Levine, Rachel M, Pruett-Miller, Shondra M, Sykes, April, Temirov, Jamshid, Cheney, Richard E, Mori, Motomi, Robinson, Camenzind G, Ogden, Stacey K

“…Morphogens function in concentration-dependent manners to instruct cell fate during tissue patterning. The cytoneme morphogen transport model posits that…”
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Restoration of lymphatic function rescues obesity in Prox1-haploinsufficient mice by Escobedo, Noelia, Proulx, Steven T, Karaman, Sinem, Dillard, Miriam E, Johnson, Nicole, Detmar, Michael, Oliver, Guillermo

“…heterozygous mice have a defective lymphatic vasculature and develop late-onset obesity. Chyle abnormally leaks from those vessels, accumulates in the…”
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Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity by Oliver, Guillermo, Harvey, Natasha L, Srinivasan, R Sathish, Dillard, Miriam E, Johnson, Nicole C, Witte, Marlys H, Boyd, Kelli, Sleeman, Mark W

“…Multiple organs cooperate to regulate appetite, metabolism, and glucose and fatty acid homeostasis. Here, we identified and characterized lymphatic vasculature…”
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Sonic Hedgehog activates prostaglandin signaling to stabilize primary cilium length by Ansari, Shariq S, Dillard, Miriam E, Zhang, Yan, Austria, Mary Ashley, Boatwright, Naoko, Shelton, Elaine L, Stewart, Daniel P, Johnson, Amanda, Wang, Christina E, Young, Brandon M, Rankovic, Zoran, Hansen, Baranda S, Pruett-Miller, Shondra M, Carisey, Alexandre F, Schuetz, John D, Robinson, Camenzind G, Ogden, Stacey K

“…Sonic Hedgehog (SHH) is a driver of embryonic patterning that, when corrupted, triggers developmental disorders and cancers. SHH effector responses are…”
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Cytoneme signaling provides essential contributions to mammalian tissue patterning by Hall, Eric T, Dillard, Miriam E, Cleverdon, Elizabeth R, Zhang, Yan, Daly, Christina A, Ansari, Shariq S, Wakefield, Randall, Stewart, Daniel P, Pruett-Miller, Shondra M, Lavado, Alfonso, Carisey, Alex F, Johnson, Amanda, Wang, Yong-Dong, Selner, Emma, Tanes, Michael, Ryu, Young Sang, Robinson, Camenzind G, Steinberg, Jeffrey, Ogden, Stacey K

“…During development, morphogens pattern tissues by instructing cell fate across long distances. Directly visualizing morphogen transport in situ has been…”
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Fixation of Embryonic Mouse Tissue for Cytoneme Analysis by Hall, Eric T, Daly, Christina A, Zhang, Yan, Dillard, Miriam E, Ogden, Stacey K

“…Developmental tissue patterning and postdevelopmental tissue homeostasis depend upon controlled delivery of cellular signals called morphogens. Morphogens act…”
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Sonic Hedgehog Activates Phospholipase A2 to Enhance Smoothened Ciliary Translocation by Arensdorf, Angela M., Dillard, Miriam E., Menke, Jacob M., Frank, Matthew W., Rock, Charles O., Ogden, Stacey K.

“…The G protein-coupled receptor Smoothened (Smo) is the signal transducer of the Sonic Hedgehog (Shh) pathway. Smo signals through G protein-dependent and…”
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Canal cristae growth and fiber extension to the outer hair cells of the mouse ear require Prox1 activity by Fritzsch, Bernd, Dillard, Miriam, Lavado, Alfonso, Harvey, Natasha L, Jahan, Israt

“…The homeobox gene Prox1 is required for lens, retina, pancreas, liver, and lymphatic vasculature development and is expressed in inner ear supporting cells and…”
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Prox1 maintains muscle structure and growth in the developing heart by Risebro, Catherine A, Searles, Richelle G, Melville, Athalie A D, Ehler, Elisabeth, Jina, Nipurna, Shah, Sonia, Pallas, Jacky, Hubank, Mike, Dillard, Miriam, Harvey, Natasha L, Schwartz, Robert J, Chien, Kenneth R, Oliver, Guillermo, Riley, Paul R

“…Impaired cardiac muscle growth and aberrant myocyte arrangement underlie congenital heart disease and cardiomyopathy. We show that cardiac-specific…”
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Lymph sacs are not required for the initiation of lymph node formation by Vondenhoff, Mark F, van de Pavert, Serge A, Dillard, Miriam E, Greuter, Mascha, Goverse, Gera, Oliver, Guillermo, Mebius, Reina E

“…The lymphatic vasculature drains lymph fluid from the tissue spaces of most organs and returns it to the blood vasculature for recirculation. Before reaching…”
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The Proxi-Vegfr3 feedback loop maintains the identity and the number of lymphatic endothelial cell progenitors by Srinivasan, R Sathish, Escobedo, Noelia, Yang, Ying, Interiano, Ashley, Dillard, Miriam E, Finkelstein, David, Mukatira, Suraj, Gil, Hyea Jin, Nurmi, Harri, Alitalo, Kari, Oliver, Guillermo

“…The mammalian lymphatic vasculature is important for returning fluids from the extracellular tissue milieu back to the blood circulation. We showed previously…”
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Cellular and molecular mechanisms controlling lymphatic vasculature development in mammals by Oliver, Guillermo C., Sathish Srinivasan, R., Johnson, Nicole, Dillard, Miriam

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Prox1 maintains muscle structure and growth in the developing heart by Risebro, Catherine A., Searles, Richelle G., Melville, Athalie A. D., Ehler, Elisabeth, Jina, Nipurna, Shah, Sonia, Pallas, Jacky, Hubank, Mike, Dillard, Miriam, Harvey, Natasha L., Schwartz, Robert J., Chien, Kenneth R., Oliver, Guillermo, Riley, Paul R.

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