Search Results - "Dilberger, Benjamin"
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Cerebral Mitochondrial Function and Cognitive Performance during Aging: A Longitudinal Study in NMRI Mice
Published in Oxidative medicine and cellular longevity (2020)“…Brain aging is one of the major risk factors for the development of several neurodegenerative diseases. Therefore, mitochondrial dysfunction plays an important…”
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A Walnut Diet in Combination with Enriched Environment Improves Cognitive Function and Affects Lipid Metabolites in Brain and Liver of Aged NMRI Mice
Published in Neuromolecular medicine (01-03-2021)“…This in vivo study aimed to test if a diet enriched with 6% walnuts alone or in combination with physical activity supports healthy ageing by changing the…”
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Betaine reduces β-amyloid-induced paralysis through activation of cystathionine-β-synthase in an Alzheimer model of Caenorhabditis elegans
Published in Genes & nutrition (27-07-2018)“…The neurodegenerative disorder Alzheimer's disease is caused by the accumulation of toxic aggregates of β-amyloid in the human brain. On the one hand,…”
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SK channel-mediated metabolic escape to glycolysis inhibits ferroptosis and supports stress resistance in C. elegans
Published in Cell death & disease (23-04-2020)“…Metabolic flexibility is an essential characteristic of eukaryotic cells in order to adapt to physiological and environmental changes. Especially in mammalian…”
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Polyphenols and Metabolites Enhance Survival in Rodents and Nematodes-Impact of Mitochondria
Published in Nutrients (13-08-2019)“…(1) Background: Polyphenols (PP) play an important role in the prevention of non-communicable diseases and may contribute to healthy aging. To investigate the…”
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Phenolic acid metabolites of polyphenols act as inductors for hormesis in C. elegans
Published in Mechanisms of ageing and development (01-09-2021)“…Phenolic acids as metabolites from polyphenols and especially vanilic acid induce the expression of genes involved in hormetic pathways including sirt-2.1…”
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Purified oleocanthal and ligstroside protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing
Published in Experimental neurology (01-06-2020)“…As components of the Mediterranean diet (MedDiet) olive polyphenols may play a crucial role for the prevention of Alzheimer's disease (AD). Since mitochondrial…”
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Mitochondrial Oxidative Stress Impairs Energy Metabolism and Reduces Stress Resistance and Longevity of C. elegans
Published in Oxidative medicine and cellular longevity (2019)“…Introduction. Mitochondria supply cellular energy and are key regulators of intrinsic cell death and consequently affect longevity. The nematode Caenorhabditis…”
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Metabolic escape to glycolysis through SK channel activation inhibits ferroptosis and increases the life span of C. elegans in conditions of heat stress
Published in The FASEB journal (01-04-2019)“…Metabolic flexibility is a characteristic of essentially all cells in order to cope with environmental alterations. One example of adaptation is represented by…”
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Infertility induced by auxin in PX627 Caenorhabditis elegans does not affect mitochondrial functions and aging parameters
Published in Aging (Albany, NY.) (08-06-2020)“…is widely used for aging studies. 5-Fluoro-2´-deoxyuridine (FUdR) is commonly used to control offspring. While larvae are stopped from further development,…”
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A Walnut-enriched Diet and Physical Activity Enhanced Cognitive and Motor Function in Aged Mice (P14-010-19)
Published in Current developments in nutrition (01-06-2019)“…This study aims to investigate walnut’s effect alone and in combination with an enriched environment on brain aging of aged NMRI mice by investigation of…”
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