Search Results - "Dilber, M S"

Intercellular delivery of thymidine kinase prodrug activating enzyme by the herpes simplex virus protein, VP22 by DILBER, M. S, PHELAN, A, AINTS, A, MOHAMED, A. J, ELLIOTT, G, SMITH, C. I. E, O'HARE, P

“…We demonstrate that fusion proteins consisting of the herpes simplex virus (HSV) transport protein VP22 linked in frame to HSV thymidine kinase (tk) retain the…”
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OuaSelect, a novel ouabain-resistant human marker gene that allows efficient cell selection within 48 h by TRESCHOW, A, UNGER, C, AINTS, A, FELLDIN, U, ASCHAN, J, DILBER, M. S

“…Efficient selection of gene-modified cells is required for a number of potential gene therapy applications, as well as molecular biology studies. Ideally, a…”
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The prognostic significance of 8p21 deletion in multiple myeloma by Sutlu, T., Alici, E., Jansson, M., Wallblom, A., Dilber, M. S., Gahrton, G., Nahi, H.

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Evaluation of ex vivo expanded human NK cells on antileukemia activity in SCID-beige mice by GUIMARAES, F, GUVEN, H, DONATI, D, CHRISTENSSON, B, LJUNGGREN, H. G, BEJARANO, M. T, DILBER, M. S

“…The possibility of using natural killer (NK) cells in treatment of human hematological malignancies has increased in recent years. One factor contributing to…”
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Expansion of natural killer (NK) and natural killer-like T (NKT)-cell populations derived from patients with B-chronic lymphocytic leukemia (B-CLL): a potential source for cellular immunotherapy by Guven, H, Gilljam, M, Chambers, B J, Ljunggren, H G, Christensson, B, Kimby, E, Dilber, M S

“…B-cell chronic lymphocytic leukemia (B-CLL) is the most common leukemia in the Western world. It is currently an incurable disease, making new treatment…”
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Suicide gene therapy: possible applications in haematopoietic disorders by Dilber, M. S., Gahrton, G.

“… Dilber MS, Gahrton G (Huddinge University Hospital, Karolinska Institutet, Huddinge, Sweden). Suicide gene therapy: possible applications in haematopoietic…”
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Low-dose cyclosporine of short duration increases the risk of mild and moderate GVHD and reduces the risk of relapse in HLA-identical sibling marrow transplant recipients with leukaemia by CARLENS, S, ASCHAN, J, REMBERGER, M, DILBER, M. S, RINGDEN, O

“…Low-dose cyclosporine (CsA), starting at 1 mg/kg/day i.v. with early discontinuation, and four doses of methotrexate (MTX), was given to 82 consecutive…”
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Gap junctions promote the bystander effect of herpes simplex virus thymidine kinase in vivo by DILBER, M. S, ABEDI, M. R, CHRISTENSSON, B, BJÖRKSTRAND, B, KIDDER, G. M, NAUS, C. C. G, GAHRTON, G, SMITH, C. I. E

“…Transfer of the herpes simplex thymidine kinase gene (HSVtk) into tumor cells followed by the administration of ganciclovir (GCV) provides a potential strategy…”
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Long-term follow-up of gene-marked CD34 cells after autologous stem cell transplantation for multiple myeloma by Alici, E, Björkstrand, B, Treschow, A, Aints, A, Smith, C I E, Gahrton, G, Dilber, M S

“…Gene marking can be used to investigate if progenitor cells harvested from patients are contaminated with tumorigenic cells. It can also provide information…”
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Mapping of herpes simplex virus-1 VP22 functional domains for inter- and subcellular protein targeting by AINTS, A, GÜVEN, H, GAHRTON, G, SMITH, C. I. E, DILBER, M. S

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Mapping of herpes simplex virus-1 VP22 functional domains for inter- and subcellular protein targeting by Aints, A, Güven, H, Gahrton, G, Smith, C I, Dilber, M S

“…The herpes simplex virus 1 (HSV-1) tegument protein VP22 has been utilised as a vehicle for trafficking proteins. It has a remarkable property of exiting the…”
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Suicide Gene Therapy for Plasma Cell Tumors by Dilber, M.Siraç, Abedi, Mohammad R., Björkstrand, Bo, Christensson, Birger, Gahrton, Gösta, Xanthopoulos, Kleanthis G., Smith, C.I.Edvard

“…Suicide gene therapy for plasma cell tumors was attempted in severe combined immunodeficient (SCID) mice injected with human myeloma cell lines. Initially, a…”
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Genetically Modified Autoactivated Cells Expressing Intracellular Forms of GM‐CSF as a Model for Regulated Administration of Cytokines by Arteaga, H. J., Mohamed, A. J., Christensson, B., Mahdy, E., Gahrton, G., Smith, C. I. E., Dilber, M. S.

“…The application of cytokines for immunotherapy is frequently hampered by undesirable side effects. To avoid systemic effects, cytokines can be directly…”
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Unrelated donor stem cell transplantation after autologous transplantation : experience of a single center by ASCHAN, J, REMBERGER, M, CARLENS, S, MATTSSON, J, DILBER, M, LÖNNQVIST, B, BJÖRKSTRAND, B

“…Patients who do not respond to autologous stem cell transplantation (ASCT) have a poor prognosis. Concerns about toxicity limit the use of unrelated donor stem…”
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Suicide genes and bystander killing: local and distant effects by Dilber, M S, Smith, C I

“…The mechanism underlying suicide gene therapy is not fully resolved but seems to be complex. Results from two recent studies now demonstrate that the level of…”
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Safety analysis of ex vivo-expanded NK and NK-like T cells administered to cancer patients: a phase I clinical study by Barkholt, Lisbeth, Alici, Evren, Conrad, Reka, Sutlu, Tolga, Gilljam, Mari, Stellan, Birgitta, Christensson, Birger, Guven, Hayrettin, Björkström, Niklas K, Söderdahl, Gunnar, Cederlund, Kerstin, Kimby, Eva, Aschan, Johan, Ringdén, Olle, Ljunggren, Hans-Gustaf, Dilber, M Sirac

“…The chimeric state after allogeneic hematopoietic stem cell transplantation provides a platform for adoptive immunotherapy using donor-derived immune cells…”
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A new method for in vitro expansion of cytotoxic human CD3 −CD56 + natural killer cells by Carlens, Stefan, Gilljam, Mari, Chambers, Benedict J, Aschan, Johan, Guven, Hayrettin, Ljunggren, Hans-Gustaf, Christensson, Birger, Dilber, M.Sirac

“…Adoptive transfer of immunocompetent cells may induce anti-tumor effects in vivo. However, a significant obstacle to the development of successful cellular…”
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Gene marking and gene therapy in multiple myeloma by Gahrton, G, Björkstrand, B, Dilber, M S, Sundman-Engberg, B, Ljungman, P, Smith, C I

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Retroviral-mediated gene transfer into human bone marrow stromal cells: studies of efficiency and in vivo survival in SCID mice by Li, K J, Dilber, M S, Abedi, M R, Björkstrand, B, Smith, C I, Garoff, H, Gahrton, G, Xanthopoulos, K G

“…Retroviral-mediated gene transfer into bone marrow cells is extensively used in gene therapy protocols. Cytokines are needed for stimulation, to achieve a high…”
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Retroviral-mediated gene transfer of CD34-enriched bone marrow and peripheral blood cells during autologous stem cell transplantation for multiple myeloma by Björkstrand, B, Gahrton, G, Dilber, M S, Ljungman, P, Smith, C I, Xanthopoulos, K G

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