Search Results - "Dik, W. A."

Elevated levels of tumour necrosis factor (TNF)-α, interleukin (IL)-1β and IL-10 in hidradenitis suppurativa skin: a rationale for targeting TNF-α and IL-1β by van der Zee, H.H., de Ruiter, L., van den Broecke, D.G., Dik, W.A., Laman, J.D., Prens, E.P.

“…Summary Background  The pathogenesis of hidradenitis suppurativa (HS) is largely unknown and the disease is difficult to treat. Patients are in high need of an…”
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Adalimumab (antitumour necrosis factor-α) treatment of hidradenitis suppurativa ameliorates skin inflammation: an in situ and ex vivo study by van der Zee, H.H., Laman, J.D., de Ruiter, L., Dik, W.A., Prens, E.P.

“…Summary Background  Hidradenitis suppurativa (HS) is a difficult‐to‐manage disease. Randomized controlled trials with antitumour necrosis factor (TNF)‐α…”
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Obesity-associated T-cell and macrophage activation improve partly after a lifestyle intervention by van der Zalm, I. J. B., van der Valk, E. S., Wester, V. L., Nagtzaam, N. M. A., van Rossum, E. F. C., Leenen, P. J. M., Dik, W. A.

“…Background The relation between low-grade inflammation and metabolic dysfunction in obesity is not fully explored. Objective To evaluate immune parameters in…”
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Orbit-Infiltrating Mast Cells, Monocytes, and Macrophages Produce PDGF Isoforms that Orchestrate Orbital Fibroblast Activation in Graves' Ophthalmopathy by van Steensel, L, Paridaens, D, van Meurs, M, van Hagen, P. M, van den Bosch, W. A, Kuijpers, R. W. A. M, Drexhage, H. A, Hooijkaas, H, Dik, W. A

“…Purpose: Platelet-derived growth factors (PDGF) are regulators of fibroblast activity that may be involved in the pathophysiology of Graves' ophthalmopathy…”
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Serum Soluble Interleukin-2 Receptor Does Not Differentiate Complex Regional Pain Syndrome from Other Pain Conditions in a Tertiary Referral Setting by Dik, W. A., Stronks, D. L., Dirckx, M., Bharwani, K. D., Huygen, F. J. P. M.

“…Previously, we showed that serum soluble interleukin-2 receptor (sIL-2R) levels, a marker for T-cell activation, were higher in complex regional pain syndrome…”
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Soluble Interleukin-2 Receptor: A Potential Marker for Monitoring Disease Activity in IgG4-Related Disease by van Laar, J. A. M., van Hagen, P. M., Bansie, R. D., Eurelings, L. E. M., Karim, A. F., Dik, Wim A.

“…Background. IgG4-related disease (IgG4-RD) is a fibroinflammatory condition. T-cells play a crucial role in the pathogenesis, and therefore, serum soluble…”
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Clinical significance of soluble interleukin-2 receptor measurement in immune-mediated diseases by Dik, W A, Heron, M

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CALM-AF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes by DIK, W. A, BRAHIM, W, BRAUN, C, ASNAFI, V, DASTUGUE, N, BERNARD, O. A, VAN DONGEN, J. M, LANGERAK, A. W, MACINTYRE, E. A, DELABESSE, E

“…The t(10;11)(p13;q14-21) is found in T-ALL and acute myeloid leukemia and fuses CALM (Clathrin-Assembly protein-like Lymphoid-Myeloid leukaemia gene) to AF10…”
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PDGF Enhances Orbital Fibroblast Responses to TSHR Stimulating Autoantibodies in Graves' Ophthalmopathy Patients by van Steensel, L, Hooijkaas, H, Paridaens, D, van den Bosch, W. A, Kuijpers, R. W. A. M, Drexhage, H. A, van Hagen, P. M, Dik, W. A

“…Purpose: Thyroid-stimulating hormone receptor (TSHR) stimulating autoantibodies are associated with Graves' ophthalmopathy (GO), the orbital manifestation of…”
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Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL by PRZYBYLSKI, G. K, DIK, W. A, VAN DONGEN, J. J. M, SCHMIDT, C. A, LANGERAK, A. W, WANZECK, J, GRABARCZYK, P, MAJUNKE, S, MARTIN-SUBERO, J. I, SIEBERT, R, DÖLKEN, G, LUDWIG, W-D, VERHAAF, B

“…T-cell acute lymphoblastic leukemia (T-ALL) is associated with chromosomal aberrations characterized by juxtaposition of proto-oncogenes to T-cell receptor…”
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Are Patients at Risk for Recurrent Disease Activity After Switching From Remicade® to Remsima®? An Observational Study by Xue, Laixi, van Bilsen, K., Schreurs, M. W. J., van Velthoven, M. E. J., Missotten, T. O., Thiadens, A. A. H. J., Kuijpers, R. W. A. M., van Biezen, P., Dalm, V. A. S. H., van Laar, J. A. M., Hermans, M. A. W., Dik, W. A., van Daele, P. L. A., van Hagen, P. M.

“…Background: Since the late ‘90s, infliximab (Remicade ® ) is being used successfully to treat patients with several non-infectious immune mediated inflammatory…”
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The peripheral blood compartment in patients with Graves' disease: activated T lymphocytes and increased transitional and pre‐naive mature B lymphocytes by Van der Weerd, K., Van Hagen, P. M., Schrijver, B., Kwekkeboom, D. J., De Herder, W. W., Ten Broek, M. R. J., Postema, P. T. E., Van Dongen, J. J. M., Staal, F. J. T., Dik, W. A.

“…Summary Graves' disease (GD) is an autoimmune disease that involves aberrant B and T lymphocyte responses. Detailed knowledge about lymphocyte subpopulation…”
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Mitigation of septic shock in mice and rhesus monkeys by human chorionic gonadotrophin-related oligopeptides by Khan, N.A, Vierboom, M.P.M, van Holten - Neelen, C, Breedveld, E, Zuiderwijk-Sick, E, Khan, A, Kondova, I, Braskamp, G, Savelkoul, H.F.J, Dik, W.A, t Hart, B.A, Benner, R

“…The marked improvement of several immune-mediated inflammatory diseases during pregnancy has drawn attention to pregnancy hormones as potential therapeutics…”
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Human T-cell lines with well-defined T-cell receptor gene rearrangements as controls for the BIOMED-2 multiplex polymerase chain reaction tubes by SANDBERG, Y, VERHAAF, B, VAN GASTEL-MOL, E. J, WOLVERS-TETTERO, I. L. M, DE VOS, J, MACLEOD, R. A. F, NOORDZIJ, J. G, DIK, W. A, VAN DONGEN, J. J. M, LANGERAK, A. W

“…The BIOMED-2 multiplex polymerase chain reaction (PCR) tubes for analysis of immunoglobulin and T-cell receptor (TCR) gene rearrangements have recently been…”
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Short course dexamethasone treatment following injury inhibits bleomycin induced fibrosis in rats by Dik, W A, McAnulty, R J, Versnel, M A, Naber, B A E, Zimmermann, L J I, Laurent, G J, Mutsaers, S E

“…Background: Corticosteroids are routinely used in patients with pulmonary fibrosis. The timing for initiation of treatment is likely to be crucial for…”
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Purity for clarity: the need for purification of tumor cells in DNA microarray studies by DE RIDDER, D, VAN DER LINDEN, C. E, SCHONEWILLE, T, DIK, W. A, REINDERS, M. J. T, VAN DONGEN, J. J. M, STAAL, F. J. T

“…It is now well established that gene expression profiling using DNA microarrays can provide novel information about various types of hematological…”
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Mycophenolate mofetil hampers antibody responses to a broad range of vaccinations in kidney transplant recipients: Results from a randomized controlled study by Fatly, Z. Al, Betjes, M.G.H., Dik, W.A., Fouchier, R.A.M., Reinders, M.E.J., de Weerd, A.E.

“…To study the effect of mycophenolate mofetil (MMF) on various vaccination responses in kidney transplant recipients. In a randomized controlled trial (EudraCT…”
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Granulocytosis and thrombocytosis in renal cell carcinoma: a pro-inflammatory cytokine response originating in the tumour by VAN ROSSUM, A. P, VLASVELD, L. Th, VLASVELD, I. N, JANSEN, P. M, DIK, W. A, HOOIJKAAS, H, CASTEL, A

“…In up to 20% of patients with renal cell cancer (RCC) an inflammatory response consisting of low-grade fever, weight loss and an elevated ESR and CRP may occur…”
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An Intraocular Inflammatory Profile of Rubella Associated Uveitis by Fazil, Z., Ten Berge, J. C., Langerak, A. W., Rothova, A., Dik, W. A.

“…Purpose: To analyze intraocular cytokine levels and cell profiles in patients with rubella virus-associated uveitis (RVU). Methods: We collected intraocular…”
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Baseline TGF-β correlates with protection after immunization with Plasmodium falciparum sporozoites in the controlled human malaria infection model by de Jong, G.M., Yap, X.Z., Walk, J., Dik, W.A., McCall, M.B.B., van Genderen, P.J.J., van Hellemond, J.J., Verbon, A., Sauerwein, R.W.

“…•Healthy malaria naïve volunteers participating in controlled human malaria infection (CHMI) show a pro-inflammatory response (in particular IFN-γ) or…”
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