Search Results - "Dijk, Karin D."
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Orofacial pain and dysfunction in patients with Parkinson's disease: A scoping review
Published in European journal of pain (01-11-2022)“…Background Parkinson's disease (PD) is commonly known as a disorder that affects the smooth performance of body movements. In addition to the motor…”
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Changes in endolysosomal enzyme activities in cerebrospinal fluid of patients with Parkinson's disease
Published in Movement disorders (01-06-2013)“…ABSTRACT Parkinson's disease (PD) is characterized neuropathologically by the cytoplasmic accumulation of misfolded α‐synuclein in specific brain regions. The…”
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3
Salivation in Parkinson's disease: A scoping review
Published in Gerodontology (01-03-2023)“…Objectives We aimed to provide an overview of the available literature that includes both objective assessments (namely hypersalivation and hyposalivation) and…”
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Deletions at 22q11.2 in idiopathic Parkinson's disease: a combined analysis of genome-wide association data
Published in Lancet neurology (01-05-2016)“…Summary Background Parkinson's disease has been reported in a small number of patients with chromosome 22q11.2 deletion syndrome. In this study, we screened a…”
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Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson's disease
Published in Molecular neurodegeneration (19-01-2016)“…Despite decades of intensive research, to date, there is no accepted diagnosis for Parkinson's disease (PD) based on biochemical analysis of blood or CSF…”
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Parkinson’s disease, temporomandibular disorder pain and bruxism and its clinical consequences: a protocol of a single-centre observational outpatient study
Published in BMJ open (18-04-2022)“…IntroductionA recent questionnaire-based study suggested that bruxism and painful temporomandibular disorders (TMD pain) may be more prevalent in patients with…”
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Inflammatory Blood Biomarkers Are Associated with Long-Term Clinical Disease Severity in Parkinson's Disease
Published in International journal of molecular sciences (01-10-2023)“…An altered immune response has been identified as a pathophysiological factor in Parkinson's disease (PD). We aimed to identify blood immunity-associated…”
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Genome-wide association study confirms extant PD risk loci among the Dutch
Published in European journal of human genetics : EJHG (01-06-2011)“…In view of the population-specific heterogeneity in reported genetic risk factors for Parkinson's disease (PD), we conducted a genome-wide association study…”
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Clinicians’ view on the management of oral health in Parkinson’s disease patients: a qualitative study
Published in BDJ open (12-05-2023)“…Background due to numerous motor and non-motor symptoms, dental treatment in patients with Parkinson’s Disease (PD) can be challenging. Knowledge regarding…”
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Diagnostic cerebrospinal fluid biomarkers for Parkinson's disease: A pathogenetically based approach
Published in Neurobiology of disease (01-09-2010)“…Abstract The inaccuracy of the early diagnosis of Parkinson's disease (PD) has been a major incentive for studies aimed at the identification of biomarkers…”
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Cerebrospinal fluid and plasma clusterin levels in Parkinson's disease
Published in Parkinsonism & related disorders (01-12-2013)“…Abstract Clusterin is a multifunctional chaperone protein that has repeatedly been linked to Alzheimer's disease (AD) pathogenesis and, more recently, also to…”
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Parkinson's disease and oral health: A systematic review
Published in Archives of oral biology (01-07-2023)“…in patients with Parkinson's Disease (PD), oral health can be affected by motor and non-motor symptoms and/or medication use. Therefore, the aim was to…”
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The therapeutic potential of opioids in narcolepsy type 1: A systematic literature review and questionnaire study
Published in Sleep medicine (01-09-2023)“…Narcolepsy type 1 is a primary sleep disorder caused by deficient hypocretin transmission leading to excessive daytime sleepiness and cataplexy. Opioids have…”
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Clusterin Levels in Plasma Predict Cognitive Decline and Progression to Alzheimer's Disease
Published in Journal of Alzheimer's disease (26-06-2015)“…Increased clusterin levels have been reported in brain, cerebrospinal fluid (CSF), and plasma of Alzheimer's disease (AD) patients. Because changes are also…”
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Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease
Published in Proceedings of the National Academy of Sciences - PNAS (18-02-2014)“…Mutations in leucine-rich repeat kinase 2 (LRRK2) cause inherited Parkinson disease (PD), and common variants around LRRK2 are a risk factor for sporadic PD…”
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Is Disturbed Intracortical Excitability a Stable Trait of Chronic Insomnia? A Study Using Transcranial Magnetic Stimulation Before and After Multimodal Sleep Therapy
Published in Biological psychiatry (1969) (15-11-2010)“…Background Chronic insomnia is a poorly understood disorder. Risk factors for developing chronic insomnia are largely unknown, yet disturbances in brain…”
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CSF α-synuclein does not discriminate dementia with Lewy bodies from Alzheimer's disease
Published in Journal of Alzheimer's disease (01-01-2010)“…In this study, we assessed whether cerebrospinal fluid (CSF) levels of the biomarker α-synuclein have a diagnostic value in differential diagnosis of dementia…”
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The Proteome of the Locus Ceruleus in Parkinson's Disease: Relevance to Pathogenesis
Published in Brain pathology (Zurich, Switzerland) (01-07-2012)“…The locus ceruleus is among the earliest affected brain regions in Parkinson's disease (PD) showing Lewy body pathology and neuronal loss. To improve our…”
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Depressive symptoms in Parkinson's disease are related to reduced [123I]FP-CIT binding in the caudate nucleus
Published in Journal of neurology, neurosurgery and psychiatry (01-02-2014)“…Background Depression is a common neuropsychiatric symptom in Parkinson's disease (PD). In previous research, PD-related depression was associated with…”
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CSF Biomarkers Reflecting Protein Pathology and Axonal Degeneration Are Associated with Memory, Attentional, and Executive Functioning in Early-Stage Parkinson′s Disease
Published in International journal of molecular sciences (12-11-2020)“…In early-stage Parkinson′s disease (PD), cognitive impairment is common, and a variety of cognitive domains including memory, attention, and executive…”
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