Search Results - "Dihan Zhou"
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Over-activation of TLR5 signaling by high-dose flagellin induces liver injury in mice
Published in Cellular & molecular immunology (01-11-2015)“…Flagellin is a potent activator of a broad range of cell types that are involved in innate and adaptive immunity. Therefore, it is a good adjuvant candidate…”
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2
Evaluation of a plasma cell-free DNA methylation test for colorectal cancer diagnosis: a multicenter clinical study
Published in BMC medicine (08-10-2024)“…A blood-based diagnostic test is a promising strategy for colorectal cancer (CRC). The MethyDT test (IColohunter), which detects methylation levels of NTMT1…”
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3
Rab11-FIP1 and Rab11-FIP5 Regulate pIgR/pIgA Transcytosis through TRIM21-Mediated Polyubiquitination
Published in International journal of molecular sciences (01-10-2021)“…Polymeric immunoglobulin receptor (pIgR)-mediated polymeric immunoglobulin A (pIgA) transcytosis across mucosal epithelial cells plays an essential role in…”
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4
Frontline Science: Nasal epithelial GM‐CSF contributes to TLR5‐mediated modulation of airway dendritic cells and subsequent IgA response
Published in Journal of leukocyte biology (01-09-2017)“…Flagellin‐activated NECs secrete certain cytokines, particularly GM‐CSF, that convey the TLR5 signal of NECs to mucosal DCs, resulting in the subsequent IgA…”
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5
A high-dose inoculum size results in persistent viral infection and arthritis in mice infected with chikungunya virus
Published in PLoS neglected tropical diseases (01-01-2022)“…Chikungunya virus (CHIKV) is an emerging mosquito-transmitted alphavirus that leads to acute fever and chronic debilitating polyarthralgia. To date, the…”
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6
Virucidal activity of a scorpion venom peptide variant mucroporin-M1 against measles, SARS-CoV and influenza H5N1 viruses
Published in Peptides (New York, N.Y. : 1980) (01-07-2011)“…► We investigated the antiviral activities of mucroporin and optimized mucroporin-M1. ► Mucroporin and mucroporin-M1 were scorpion venom-derived host defense…”
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7
Genome-wide methylation profiling identify hypermethylated HOXL subclass genes as potential markers for esophageal squamous cell carcinoma detection
Published in BMC medical genomics (29-11-2022)“…Numerous studies have revealed aberrant DNA methylation in esophageal squamous cell carcinoma (ESCC). However, they often focused on the partial genome, which…”
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DNA methylation and gene expression profiling reveal potential association of retinol metabolism related genes with hepatocellular carcinoma development
Published in PeerJ (San Francisco, CA) (23-08-2024)“…Aberrant DNA methylation patterns play a critical role in the development of hepatocellular carcinoma (HCC). However, the molecular mechanisms associated with…”
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9
Anti-HIV-1 activity of a new scorpion venom peptide derivative Kn2-7
Published in PloS one (19-04-2012)“…For over 30 years, HIV/AIDS has wreaked havoc in the world. In the absence of an effective vaccine for HIV, development of new anti-HIV agents is urgently…”
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10
Longitudinal Characteristics of T Cell Responses in Asymptomatic SARS-CoV-2 Infection
Published in Virologica Sinica (01-12-2020)Get full text
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11
Development of a New Reverse Genetics System for Ebola Virus
Published in mSphere (05-05-2021)“…Ebola virus (EBOV) is a highly pathogenic negative-stranded RNA virus that has caused several deadly endemics in the past decades. EBOV reverse genetics…”
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12
Activation of NLRC4 downregulates TLR5-mediated antibody immune responses against flagellin
Published in Cellular & molecular immunology (01-07-2016)“…Bacterial flagellin is a unique pathogen-associated molecular pattern (PAMP), which can be recognized by surface localized Toll-like receptor 5 (TLR5) and the…”
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13
Characteristics of T‐cell responses in COVID‐19 patients with prolonged SARS‐CoV‐2 positivity – a cohort study
Published in Clinical & translational immunology (2021)“…Objective SARS‐CoV‐2 has caused a worldwide pandemic of COVID‐19. The existence of prolonged SARS‐CoV‐2 positivity (PP) has further increased the burden on the…”
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14
Matrix Protein-Specific IgA Antibody Inhibits Measles Virus Replication by Intracellular Neutralization
Published in Journal of Virology (01-11-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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15
Unpolarized release of vaccinia virus and HIV antigen by colchicine treatment enhances intranasal HIV antigen expression and mucosal humoral responses
Published in PloS one (15-09-2011)“…The induction of a strong mucosal immune response is essential to building successful HIV vaccines. Highly attenuated recombinant HIV vaccinia virus can be…”
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16
L-Selectin and P-Selectin Are Novel Biomarkers of Cervicovaginal Inflammation for Preclinical Mucosal Safety Assessment of Anti-HIV-1 Microbicide
Published in Antimicrobial Agents and Chemotherapy (01-06-2012)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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17
A safe and effective mucosal RSV vaccine in mice consisting of RSV phosphoprotein and flagellin variant
Published in Cell reports (Cambridge) (20-07-2021)“…Respiratory syncytial virus (RSV) is a major cause of serious acute lower respiratory tract infection in infants and the elderly. The lack of a licensed RSV…”
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18
A high-dose inoculum size results in persistent viral infection and arthritis in mice infected with chikungunya virus
Published in PLoS neglected tropical diseases (01-01-2022)“…Chikungunya virus (CHIKV) is an emerging mosquito-transmitted alphavirus that leads to acute fever and chronic debilitating polyarthralgia. To date, the…”
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19
Second-generation Flagellin-rPAc Fusion Protein, KFD2-rPAc, Shows High Protective Efficacy against Dental Caries with Low Potential Side Effects
Published in Scientific reports (11-09-2017)“…Dental caries is one of the most common global chronic diseases affecting all ages of the population; thus a vaccine against caries is urgently needed. Our…”
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20
Broad phenotypic alterations and potential dysfunction of lymphocytes in individuals clinically recovered from COVID-19
Published in Journal of molecular cell biology (06-07-2021)“…Although millions of patients have clinically recovered from COVID-19, little is known about the immune status of lymphocytes in these individuals. In this…”
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