Search Results - "Dignass, A. U."

Escherichia coli Strain Nissle 1917 Ameliorates Experimental Colitis via Toll-Like Receptor 2- and Toll-Like Receptor 4-Dependent Pathways by Grabig, A, Paclik, D, Guzy, C, Dankof, A, Baumgart, D.C, Erckenbrecht, J, Raupach, B, Sonnenborn, U, Eckert, J, Schumann, R.R, Wiedenmann, B, Dignass, A.U, Sturm, A

“…Toll-like receptors (TLRs) are key components of the innate immune system that trigger antimicrobial host defense responses. The aim of the present study was…”
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Rescue therapy with tacrolimus is effective in patients with severe and refractory inflammatory bowel disease by Baumgart, D. C., Wiedenmann, B., Dignass, A. U.

“…Summary Background : Oral tacrolimus, approved for the prophylaxis of organ rejection in liver or kidney transplants, has been reported to be effective in…”
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Patients with active inflammatory bowel disease lack immature peripheral blood plasmacytoid and myeloid dendritic cells by Baumgart, D C, Metzke, D, Schmitz, J, Scheffold, A, Sturm, A, Wiedenmann, B, Dignass, A U

“…Background: Breakdown of tolerance against the commensal microflora is believed to be a major factor in the pathogenesis of inflammatory bowel disease (IBD)…”
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Clinical trial: five or ten cycles of granulocyte–monocyte apheresis show equivalent efficacy and safety in ulcerative colitis by DIGNASS, A. U., ERIKSSON, A., KILANDER, A., PUKITIS, A., RHODES, J. M., VAVRICKA, S.

“…Aliment Pharmacol Ther 31, 1286–1295 Summary Background  Ulcerative colitis is characterized by leucocyte infiltration into the colonic mucosa…”
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Clinical relevance of transabdominal ultrasonography and magnetic resonance imaging in patients with inflammatory bowel disease of the terminal ileum and large bowel by Pascu, M., Roznowski, A. B., Müller, H‐P., Adler, A., Wiedenmann, B., Dignass, A. U.

“…Background: Ileocolonoscopy represents the diagnostic standard in the work‐up of patients with inflammatory bowel diseases (IBD). Patients are often reluctant…”
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Cytokine modulation of intestinal epithelial cell restitution: central role of transforming growth factor beta by Dignass, A U, Podolsky, D K

“…After various forms of superficial injury, mucosal integrity is re-established by rapid migration of epithelial cells across the wound margins in a process…”
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Uneventful pregnancy and neonatal outcome with tacrolimus in refractory ulcerative colitis by Baumgart, D C, Sturm, A, Wiedenmann, B, Dignass, A U

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Modulation of intestinal epithelial wound healing in vitro and in vivo by lysophosphatidic acid by Sturm, Andreas, Sudermann, Thomas, Schulte, Klaus–Martin, Goebell, Harald, Dignass, Axel U.

“…Background & Aims: Lysophosphatidic acid (LPA) is assumed to play an important role in the modulation of injury and tissue repair in nonepithelial tissues. The…”
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Bone Loss in Patients with Inflammatory Bowel Disease Is Less Than Expected: A Follow-up Study by SCHULTE, C, DIGNASS, A. U, MANN, K, GOEBELL, H

“…In spite of the accumulating evidence of an increased prevalence of osteopenia and osteoporosis in patients with inflammatory bowel diseases (IBD), the time…”
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Effects of exogenous zinc supplementation on intestinal epithelial repair in vitro by CARIO, E, JUNG, S, HARDER D'HEUREUSE, J, SCHULTE, C, STURM, A, WIEDENMANN, B, GOEBELL, H, DIGNASS, A. U

“…Background Substitution of zinc modulates antioxidant capabilities within the intestinal mucosa and improves intestinal wound healing in zinc‐deficient…”
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Fibroblast growth factors modulate intestinal epithelial cell growth and migration by Dignass, A U, Tsunekawa, S, Podolsky, D K

“…Various peptide growth factors have been found to exert functional effects among epithelial cell populations. This study assessed the role of certain…”
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Functional Relevance of Activin A in the Intestinal Epithelium by Dignass, A. U., Jung, S., Harder-d'Heureuse, J., Wiedenmann, B.

“…Background: Activin A modulates inflammation and repair in various tissues. The aim of this study was to characterize the effects of activin A on intestinal…”
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Acute epithelial injury in the rat small intestine in vivo is associated with expanded expression of transforming growth factor alpha and beta by Dignass, A U, Stow, J L, Babyatsky, M W

“…BACKGROUND--Previous studies have shown the importance of transforming growth factors alpha and beta (TGF alpha and TGF beta) in modulating epithelial cell…”
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Corticosteroids Impair Intestinal Epithelial Wound Repair Mechanisms In Vitro by Jung, S., Fehr, S., Harder-D'Heureuse, J., Wiedenmann, B., Dignass, A. U.

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Shingles following infliximab infusion by Baumgart, D C, Dignass, A U

“…DISCUSSION Adult varicella can be a severe illness complicated by pneumonia, encephalitis, hepatitis, thrombocytopenia, and prolonged fever. 3 Blood levels of…”
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A study for the evaluation of safety and tolerability of intravenous high-dose iron sucrose in patients with iron deficiency anemia due to gastrointestinal bleeding by Schröder, O, Schrott, M, Blumenstein, I, Jahnel, J, Dignass, A U, Stein, J

“…The provision of adequate iron to support erythropoiesis in iron deficient patients is a time-consuming process which may present compliance problems for…”
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Adenine nucleotides modulate epithelial wound healing in vitro by DIGNASS, A. U, BECKER, A, SPIEGLER, S, GOEBELL, H

“…Background Adenine nucleotides have been demonstrated to enhance structural and functional regeneration in experimental renal injury in rats. The mechanisms of…”
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Current position on Vedolizumab for ulcerative colitis and Crohn's disease by Schreiber, S, Dignass, A U, Hartmann, H, Kruis, W, Rogler, G, Siegmund, B, Stallmach, A, Witte, C, Bokemeyer, B

“…Vedolizumab, the first drug in the class of anti-integrin molecules, is newly approved for ulcerative colitis and Crohn's disease and can be prescribed in…”
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Mechanisms and modulation of intestinal epithelial repair by Dignass, Axel U.

“…The mucosal epithelium of the alimentary tract represents a crucial barrier to a broad spectrum of noxious and immunogenic substances within the intestinal…”
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Mycophenolate mofetil reduces tissue damage and inflammation in an experimental model of colitis in rats by ZEEH, J. M, ZORLU, I, RILEY, N. E, HOFFMANN, P, RUWE, M, GOEBELL, H, GERKEN, G, DIGNASS, A. U

“…Lymphocytes are widely believed to be responsible for persistent intestinal inflammation in inflammatory bowel diseases. Mycophenolate mofetil (MMF) is a…”
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