Search Results - "Dignan, R J"

Limiting edema in neonatal cardiopulmonary bypass with narrow-range molecular weight hydroxyethyl starch by Yeh, Jr, T, Parmar, J M, Rebeyka, I M, Lofland, G K, Allen, E L, Dignan, R J, Dyke, C M, Wechsler, A S

“…The marked edema observed in neonatal cardiopulmonary bypass is thought to result from pathologic increases in capillary permeability. Pentafraction is a…”
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Effects of dynamic cardiomyoplasty on left ventricular performance and myocardial mechanics in dilated cardiomyopathy by Lee, K F, Dignan, R J, Parmar, J M, Dyke, C M, Benton, G, Yeh, Jr, T, Abd-Elfattah, A S, Wechsler, A S

“…We tested the hypothesis that dynamic cardiomyoplasty produces beneficial changes in the functional mechanics of the dilated, failing left ventricle. Chronic…”
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Reactivity of gastroepiploic and internal mammary arteries. Relevance to coronary artery bypass grafting by Dignan, R J, Yeh, Jr, T, Dyke, C M, Lee, K F, Lutz, 3rd, H A, Ding, M, Wechsler, A S

“…The gastroepiploic artery is an alternate conduit for coronary artery bypass grafting. To test the hypothesis that its vasoreactive properties are different…”
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Microvascular dysfunction after myocardial ischemia by Dignan, Rebecca J., Kadletz, Margit, Dyke, Cornelius M., Lutz, Harry A., Yeh, Thomas, Wechsler, Andrew S.

“…Endothelium-mediated relaxation and smooth muscle function in large coronary arteries are resistant to prolonged global ischemia. We used a small-vessel…”
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Coronary artery endothelial cell and smooth muscle dysfunction after global myocardial ischemia by Dignan, Rebecca J., Dyke, Cornelius M., Abd-Elfattah, Anwar S., Lutz, Harry A., Yeh, Thomas, Lee, K.Francis, Parmar, Jitendra, Wechsler, Andrew S.

“…We hypothesized that coronary artery endothelial cell function and smooth muscle function are modified by global myocardial ischemia and used…”
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Reactivity to alpha agonists is heightened in immature porcine pulmonary arteries by Kadletz, Margit, Dignan, Rebecca J., Wechsler, Andrew S.

“…Pulmonary hypertension after cardiopulmonary bypass is a common problem in pediatric cardiac operations. This study tested the hypothesis that there is a…”
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Ischemia and activated neutrophils alter coronary microvascular but not epicardial coronary artery reactivity by Kadletz, Margit, Dignan, Rebecca J., Loesser, Kathryn E., Hess, Michael L., Wechsler, Andrew S.

“…Activated neutrophils have been implicated in reperfusion injury and the no-reflow phenomenon of intramyocardial arterioles. This study tested the hypothesis…”
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Pulmonary Artery Endothelial Cell Function in Swine Pseudomonas Sepsis by Kadletz, Margit, Dignan, Rebecca J., Mullen, Patrick G., Windsor, Alastair C.J., Sugerman, Harvey J., Wechsler, Andrew S.

“…A substantial increase in pulmonary vascular resistance is associated with sepsis and its sequelae (sepsis syndrome and septic shock). It is postulated that…”
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Coronary vasomotor dysfunction following hemorrhagic shock by Dignan, R J, Wechsler, A S, DeMaria, E J

“…Myocardial dysfunction and subendocardial ischemia have been described during hemorrhagic shock, but technical limitations have precluded the in vitro…”
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Efficacy of a hydroxyl radical scavenger (VF 233) in preventing reperfusion injury in the isolated rabbit heart by Ding, Mai, Dyke, Cornelius M., Abd-elfattah, Anwar S., Lehman, Ionathan D., Dignan, Rebecca J., Wechsler, Andrew S.

“…We tested the hypothesis that 3,4,5,-trihydroxybenzamidoxime (VF 233), a demonstrated hydroxyl radical scavenger and an effective Fe 3+ chelator, attenuates…”
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Ultra-low dose aprotinin decreases transfusion requirements and is cost effective in coronary operations by Dignan, Rebecca J, Law, David W, Seah, Peng W, Manganas, Con W, Newman, David C, Grant, Peter W, Wolfenden, Hugh D

“…Background. The recommended dose of aprotinin has been shown to reduce blood loss and need for blood transfusions, but the cost precludes its routine use. This…”
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Does a combined procedure for cardiac surgery and thyroidectomy offer acceptable outcomes? by De Silva, Ramesh P., Dignan, Rebecca J.

“…This best evidence topic on cardiothoracic surgery was written using a structured protocol. The question addressed was: ‘in an adult patient requiring cardiac…”
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Orotic acid improves recovery of left ventricular function days after heterotopic transplantation by YEH, T. JR, REBEYKA, I, JAKOI, E. R, JOHNSON, D. E, DIGNAN, R. J, DYKE, C. M, WECHSLER, A. S

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Effects of triiodothyronine supplementation after myocardial ischemia by Dyke, Cornelius M., Ding, Mai, Abd-Elfattah, Anwar S., Loesser, Kathy, Dignan, Rebecca J., Wechsler, Andrew S., Salter, David R.

“…Cardiopulmonary bypass causes a “euthyroid-sick” state characterized by low levels of circulating triiodothyronine. Triiodothyronine supplementation in this…”
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The influence of age and sex on human internal mammary artery size and reactivity by Dignan, Rebecca J., Yeh, Thomas, Dyke, Cornelius M., Lutz, Harry A., Wechsler, Andrew S.

“…Internal mammary arteries (IMAs) from women and the elderly have been postulated to be smaller and more reactive than IMAs from men and younger patients and,…”
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Orotic acid improves left ventricular recovery four days after heterotopic transplantation by Yeh, Thomas, Rebeyka, Ivan M., Jakoi, Emma R., Johnson, Danna E., Dignan, Rebecca J., Dyke, Cornelius M., Wechsler, Andrew S.

“…Orotic acid accelerates compensatory myocardial hypertrophy after regional ischemia and improves left ventricular function acutely after global ischemia. In…”
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Inotropic stimulation and oxygen consumption in a canine model of dilated cardiomyopathy by Dyke, Cornelius M., Lee, K.Francis, Parmar, Jitendra, Dignan, Rebecca J., Yeh, Thomas, Abd-Elfattah, Anwar, Wechsler, Andrew S.

“…Inotropic support for the dilated, failing ventricle results in complex hemodynamic changes affecting preload, afterload, contractility, and heart rate, each…”
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Penetrating injury to the heart requiring cardiopulmonary bypass: a case study by Webb, D P, Ramsey, J J, Dignan, R J, Drinkwater, Jr, D C

“…Penetrating wounds to the heart represent a significant surgical challenge because of their unique clinical course and the need for emergent operative care…”
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Left ventricular assist device implantation via left thoracotomy: alternative to repeat sternotomy by Pierson, Richard N., Howser, Renee, Donaldson, Terri, Merrill, Walter H., Dignan, Rebecca J., Drinkwater, Davis C., Christian, Karla G., Butler, Javed, Chomsky, Don, Wilson, John R., Clark, Rick, Davis, Stacy F.

“…Repeat sternotomy for left ventricular assist device insertion may result in injury to the right heart or patent coronary grafts, complicating intraoperative…”
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Microvascular dysfunction after myocardial ischemia. Discussion by DIGNAN, R. J, KADLETZ, M, DYKE, C. M, LUTZ, H. A, YEH, T. JR, WECHSLER, A. S, VERRIER, E. D

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