Search Results - "Diglio, C A"

Mitogen‐activated protein kinase (MAPK) regulates the expression of progelatinase B (MMP‐9) in breast epithelial cells by Reddy, Kaladhar B., Krueger, Joseph S., B. Kondapaka, Sudhir, Diglio, Clement A.

“…Mitogen‐activated protein kinases (MAPKs) play a major role in the mitogenic signal transduction pathway and are essential components of both growth and…”
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Endothelin stimulates protein synthesis in smooth muscle cells by Chua, B H, Krebs, C J, Chua, C C, Diglio, C A

“…The present work was carried out to assess the effect of endothelin on the relative synthesis of protein, RNA, and DNA in confluent rat aortic smooth muscle…”
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Identification of PECAM-1 in solid tumor cells and its potential involvement in tumor cell adhesion to endothelium by Tang, D.G., Chen, Y.Q., Newman, P.J., Shi, L, Gao, X, Diglio, C.A., Honn, K.V.

“…PECAM-1 (CD31/EndoCAM) is an adhesion molecule in the immunoglobulin supergene family that is expressed on endothelial cells, platelets, and some hematopoietic…”
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Angiogenesis in rat aorta ring explant cultures by Diglio, C A, Grammas, P, Giacomelli, F, Wiener, J

“…This report describes the utilization of rat aorta "rings" as explants to study angiogenesis. Under short-term culture conditions, ring explants transferred at…”
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Bradykinin Blocks Angiotensin II-Induced Hypertrophy in the Presence of Endothelial Cells by Ritchie, Rebecca H, Marsh, James D, Lancaster, Wayne D, Diglio, Clement A, Schiebinger, Rick J

“…Angiotensin-converting enzyme inhibitors block left ventricular hypertrophy in vivo. A component of this effect has been attributed to tissue accumulation of…”
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Enhanced tumor cell adhesion to the subendothelial matrix resulting from 12(S)-HETE-induced endothelial cell retraction by Honn, K V, Grossi, I M, Diglio, C A, Wojtukiewicz, M, Taylor, J D

“…A 12-lipoxygenase metabolite of arachidonic acid, 12(S)-hydroxyeicosatetraenoic acid (12[S]-HETE), which is produced by platelets and tumor cells, was tested…”
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Lipoxygenase metabolites of arachidonic and linoleic acids modulate the adhesion of tumor cells to endothelium via regulation of protein kinase C by Liu, B, Timar, J, Howlett, J, Diglio, C A, Honn, K V

“…12(S)-hydroxyeicosatetraenoic acid (12[S]-HETE) and 13(S)-hydroxyoctadecadienoic acid (13[S]-HODE), lipoxygenase metabolites of arachidonic acid and linoleic…”
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Tumor cell-derived 12(S)-hydroxyeicosatetraenoic acid induces microvascular endothelial cell retraction by HONN, K. V, TANG, D. G, KIMLER, V. A, TAYLOR, J. D, MARNETT, L. J, GROSSI, I, DUNIEC, Z. M, TIMAR, J, RERNAUD, C, LEITHAUSER, M, BLAIR, I, JOHNSON, C. R, DIGLIO, C. A

“…Our previous work demonstrated that the 12-lipoxygenase metabolite of arachidonic acid, 12(S)-hydroxyeicosatetraenoic acid [12(S)-HETE] induced a…”
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Thrombin increases the metastatic potential of tumor cells by Wojtukiewicz, M Z, Tang, D G, Ciarelli, J J, Nelson, K K, Walz, D A, Diglio, C A, Mammen, E F, Honn, K V

“…Initial arrest of tumor cells in the microvasculature and their attachment to the endothelium and subendothelial matrix (SEM) are essential prerequisites for…”
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5-Hydroxytryptamine1-like receptors linked to increases in intracellular calcium concentration and inhibition of cyclic AMP accumulation in cultured vascular smooth muscle cells derived from bovine basilar artery by Ebersole, B J, Diglio, C A, Kaufman, D W, Berg, K A

“…Vascular smooth muscle cells derived from bovine basilar artery by the explant method were grown in culture. In the presence of 1 microM forskolin and the…”
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Inhibition of TPA and 12(S)-HETE-stimulated tumor cell adhesion by prostacyclin and its stable analogs: rationale for their antimetastatic effects by Tang, D G, Grossi, I M, Tang, K Q, Diglio, C A, Honn, K V

“…We have investigated the regulatory role of PGI2 and its stable analogs, i.e., iloprost and cicaprost, on 12(S)-HETE- and TPA-enhanced tumor cell integrin…”
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12(S)-HETE promotes tumor-cell adhesion by increasing surface expression of alpha V beta 3 integrins on endothelial cells by Tang, D G, Grossi, I M, Chen, Y Q, Diglio, C A, Honn, K V

“…The present work was undertaken to investigate the regulatory role of 12(S)-HETE, a lipoxygenase metabolite of arachidonic acid, in the surface expression of…”
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Biosynthesis of 12(S)-hydroxyeicosatetraenoic acid by B16 amelanotic melanoma cells is a determinant of their metastatic potential by Liu, B, Marnett, L J, Chaudhary, A, Ji, C, Blair, I A, Johnson, C R, Diglio, C A, Honn, K V

“…We have previously demonstrated that the metastatic potential of tumor cells can be increased by treatment with exogenous 12(S)hydroxyeicosatetraenoic acid…”
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Mesothelial cells produce a chemoattractant for lung fibroblasts: role of fibronectin by Kuwahara, M, Kuwahara, M, Bijwaard, K E, Gersten, D M, Diglio, C A, Kagan, E

“…Pleural fibrosis may complicate several types of non-exudative pleural injury. Although the pathogenesis of such lesions is poorly understood, it is…”
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Protein Kinase C-Dependent Effects of 12(S)-HETE on Endothelial Cell Vitronectin Receptor and Fibronectin Receptor by Tang, G., Chen, Yong Q., Diglio, Clement A., Honn, Kenneth V.

“…12(S)-HETE, a lipoxygenase metabolite of arachidonic acid induced a nondestructive and reversible endothelial cell (EC) retraction. 12(S)-HETE induced EC…”
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Enhanced endothelial cell retraction mediated by 12(S)-HETE: a proposed mechanism for the role of platelets in tumor cell metastasis by Honn, K V, Tang, D G, Grossi, I M, Renaud, C, Duniec, Z M, Johnson, C R, Diglio, C A

“…Platelets have been hypothesized to contribute to tumor cell metastasis, but the underlying mechanism(s) remain unknown. We demonstrate here that one mechanism…”
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Endothelial Cell Interactions With Synthetic Peptides From the Carboxyl-Terminal Heparin-Binding Domains of Fibronectin by Huebsch, Joseph C, McCarthy, James B, Diglio, Clement A, Mooradian, Daniel L

“…Fibronectin (FN) plays an important role in endothelial cell adhesion, spreading, and motility.Within FN, a number of functional domains have been identified,…”
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Low dose radiation-induced endothelial cell retraction by Kantak, S S, Diglio, C A, Onoda, J M

“…We characterized in vitro the effects of gamma-radiation (12.5-100 cGy) on pulmonary microvascular endothelial cell (PMEC) morphology and F-actin organization…”
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The lipoxygenase metabolite, 12(S)-HETE, induces a protein kinase C-dependent cytoskeletal rearrangement and retraction of microvascular endothelial cells by Tang, D G, Timar, J, Grossi, I M, Renaud, C, Kimler, V A, Diglio, C A, Taylor, J D, Honn, K V

“…We previously reported that a lipoxygenase metabolite of arachidonic acid, 12(S)-hydroxyeicosatetraenoic acid [12(S)-HETE], induced large vessel endothelial…”
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Rat heart-derived endothelial and smooth muscle cell cultures: isolation, cloning and characterization by Diglio, C A, Grammas, P, Giacomelli, F, Wiener, J

“…This report describes the initiation, cloning and establishment of long-term serial cultures of rat heart-derived vascular endothelial (EC) and smooth muscle…”
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