Search Results - "Digestive diseases and sciences"

Diet and the Human Gut Microbiome: An International Review by Wilson, Annette S., Koller, Kathryn R., Ramaboli, Matsepo C., Nesengani, Lucky T., Ocvirk, Soeren, Chen, Caixia, Flanagan, Christie A., Sapp, Flora R., Merritt, Zoe T., Bhatti, Faheem, Thomas, Timothy K., O’Keefe, Stephen J. D.

“…This review summarizes the key results of recently published studies on the effects of dietary change and nutritional intervention on the human microbiome from…”
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Disease Burden of Hepatocellular Carcinoma: A Global Perspective by Sayiner, Mehmet, Golabi, Pegah, Younossi, Zobair M.

“…Liver cancer is one of the leading causes of cancer-related mortality around the world. Hepatocellular carcinoma (HCC) is the primary cancer of the liver,…”
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Role of Dietary Fructose and Hepatic De Novo Lipogenesis in Fatty Liver Disease by Softic, Samir, Cohen, David E., Kahn, C. Ronald

“…Nonalcoholic fatty liver disease (NAFLD) is a liver manifestation of metabolic syndrome. Overconsumption of high-fat diet (HFD) and increased intake of…”
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Innate Immunity and Inflammation in NAFLD/NASH by Arrese, Marco, Cabrera, Daniel, Kalergis, Alexis M., Feldstein, Ariel E.

“…Inflammation and hepatocyte injury and death are the hallmarks of nonalcoholic steatohepatitis (NASH), the progressive form of nonalcoholic fatty liver disease…”
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Bile Acid Signaling in Inflammatory Bowel Diseases by Fiorucci, Stefano, Carino, Adriana, Baldoni, Monia, Santucci, Luca, Costanzi, Emanuele, Graziosi, Luigina, Distrutti, Eleonora, Biagioli, Michele

“…Bile acids are a group of chemically different steroids generated at the host/microbial interface. Indeed, while primary bile acids are the end-product of…”
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Healthy Human Gastrointestinal Microbiome: Composition and Function After a Decade of Exploration by Ruan, Wenly, Engevik, Melinda A., Spinler, Jennifer K., Versalovic, James

“…The human gastrointestinal (GI) tract contains communities of microbes (bacteria, fungi, viruses) that vary by anatomic location and impact human health…”
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Microbiome and Its Role in Irritable Bowel Syndrome by Pimentel, Mark, Lembo, Anthony

“…Irritable bowel syndrome (IBS) is an extremely common and often very debilitating chronic functional gastrointestinal disorder. Despite its prevalence,…”
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Liver Transplantation for Nonalcoholic Steatohepatitis in the US: Temporal Trends and Outcomes by Cholankeril, George, Wong, Robert J., Hu, Menghan, Perumpail, Ryan B., Yoo, Eric R., Puri, Puneet, Younossi, Zobair M., Harrison, Stephen A., Ahmed, Aijaz

“…Background and Aims Nonalcoholic steatohepatitis (NASH) is a rapidly growing etiology of end-stage liver disease in the US. Temporal trends and outcomes in…”
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Changing Epidemiology of Upper Gastrointestinal Hemorrhage in the Last Decade: A Nationwide Analysis by Wuerth, Brandon A., Rockey, Don C.

“…Background Upper gastrointestinal hemorrhage (UGIH) is common and carries substantial mortality requiring frequent hospitalizations. Aim To investigate trends…”
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Empagliflozin for the Treatment of Nonalcoholic Steatohepatitis in Patients with Type 2 Diabetes Mellitus by Lai, Lee-Lee, Vethakkan, Shireene Ratna, Nik Mustapha, Nik Raihan, Mahadeva, Sanjiv, Chan, Wah-Kheong

“…Background and Aims Sodium-glucose cotransporter-2 (SGLT2) inhibitors are a novel class of drugs that lower glucose by inducing renal glycosuria. We aimed to…”
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Racial and Socioeconomic Disparities in Utilization of Telehealth in Patients with Liver Disease During COVID-19 by Wegermann, Kara, Wilder, Julius M., Parish, Alice, Niedzwiecki, Donna, Gellad, Ziad F., Muir, Andrew J., Patel, Yuval A.

“…Background and Aims The coronavirus disease 2019 (COVID-19) pandemic resulted in a rapid expansion of telehealth services in hepatology. However, known racial…”
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Altered Bile Acid Metabolome in Patients with Nonalcoholic Steatohepatitis by Ferslew, Brian C., Xie, Guoxiang, Johnston, Curtis K., Su, Mingming, Stewart, Paul W., Jia, Wei, Brouwer, Kim L. R., Sidney Barritt, A.

“…Background and Aims The prevalence of nonalcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH) is increasing at an alarming rate. The role of bile…”
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Microbial-Based and Microbial-Targeted Therapies for Inflammatory Bowel Diseases by Oka, Akihiko, Sartor, R. Balfour

“…Inflammatory bowel diseases (IBD), including Crohn’s disease, ulcerative colitis, and pouchitis, are chronic, relapsing intestinal inflammatory disorders…”
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Convolutional Neural Network for Differentiating Gastric Cancer from Gastritis Using Magnified Endoscopy with Narrow Band Imaging by Horiuchi, Yusuke, Aoyama, Kazuharu, Tokai, Yoshitaka, Hirasawa, Toshiaki, Yoshimizu, Shoichi, Ishiyama, Akiyoshi, Yoshio, Toshiyuki, Tsuchida, Tomohiro, Fujisaki, Junko, Tada, Tomohiro

“…Background Early detection of early gastric cancer (EGC) allows for less invasive cancer treatment. However, differentiating EGC from gastritis remains…”
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Efficacy of Single-Strain Probiotics Versus Multi-Strain Mixtures: Systematic Review of Strain and Disease Specificity by McFarland, Lynne V.

“…The diversity of probiotic products makes choosing an appropriate probiotic challenging. One unanswered question is whether single-strain probiotics are more…”
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The “Leaky Gut”: Tight Junctions but Loose Associations? by Hollander, Daniel, Kaunitz, Jonathan D.

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Overlap of Irritable Bowel Syndrome and Functional Dyspepsia in the Clinical Setting: Prevalence and Risk Factors by von Wulffen, Moritz, Talley, Nicholas J., Hammer, Johann, McMaster, Jessica, Rich, Graeme, Shah, Ayesha, Koloski, Natasha, Kendall, Bradley J., Jones, Mike, Holtmann, Gerald

“…Background According to Rome IV criteria, functional dyspepsia (FD) and irritable bowel syndrome (IBS) are distinct functional gastrointestinal disorders…”
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Butyrate Enhances Intestinal Epithelial Barrier Function via Up-Regulation of Tight Junction Protein Claudin-1 Transcription by Wang, Hong-Bo, Wang, Peng-Yuan, Wang, Xin, Wan, Yuan-Lian, Liu, Yu-Cun

“…Background Barrier function is essential for the maintenance of normal intestinal function. Dysregulation of the intestinal barrier underlies a wide range of…”
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Seven-Year Efficacy and Safety of Treatment with Tenofovir Disoproxil Fumarate for Chronic Hepatitis B Virus Infection by Buti, Maria, Tsai, Naoky, Petersen, Joerg, Flisiak, Robert, Gurel, Selim, Krastev, Zahary, Aguilar Schall, Raul, Flaherty, John F., Martins, Eduardo B., Charuworn, Prista, Kitrinos, Kathryn M., Mani Subramanian, G., Gane, Edward, Marcellin, Patrick

“…Background Long-term tenofovir disoproxil fumarate (TDF) treatment for chronic hepatitis B (CHB) is associated with sustained viral suppression and regression…”
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Direct Oral Anticoagulants in Cirrhosis Patients Pose Similar Risks of Bleeding When Compared to Traditional Anticoagulation by Intagliata, N. M., Henry, Z. H., Maitland, H., Shah, N. L., Argo, C. K., Northup, P. G., Caldwell, S. H.

“…Background and Aims Direct oral anticoagulants (DOAC) are important new anticoagulant therapies that are not well studied in patients with chronic liver…”
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