Search Results - "Digby, J. E."

Orexin receptor expression in human adipose tissue: effects of orexin-A and orexin-B by Digby, J E, Chen, J, Tang, J Y, Lehnert, H, Matthews, R N, Randeva, H S

“…Orexin-A and orexin-B, via their receptors orexin-1 receptor (OX1R) and orexin-2 receptor (OX2R) have been shown to play a role in the regulation of feeding,…”
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Depot- and sex-specific differences in human leptin mRNA expression: implications for the control of regional fat distribution by Montague, C. T., Prins, J. B., Sanders, L., Digby, J. E., O'Rahilly, S.

“…Depot- and sex-specific differences in human leptin mRNA expression: implications for the control of regional fat distribution. C T Montague , J B Prins , L…”
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Upregulation of adiponectin receptor 1 and 2 mRNA and protein in adipose tissue and adipocytes in insulin-resistant women with polycystic ovary syndrome by TAN, B. K, CHEN, J, DIGBY, J. E, KEAY, S. D, KENNEDY, C. R, RANDEVA, H. S

“…Polycystic ovary syndrome (PCOS) is a multifaceted metabolic disease linked with insulin resistance (IR) and obesity. Adiponectin, which is lower in IR states,…”
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Regulation of tumour necrosis factor-alpha release from human adipose tissue in vitro by Sewter, CP, Digby, JE, Blows, F, Prins, J, O'Rahilly, S

“…Tumour necrosis factor-alpha (TNF-alpha), secreted by cells of the macrophage-monocyte lineage, has a well established role in inflammation and host-defence…”
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Congenital leptin deficiency is associated with severe early-onset obesity in humans by O'Rahilly, Stephen, Montague, Carl T, Farooqi, I. Sadaf, Whitehead, Jonathan P, Soos, Maria A, Rau, Harald, Wareham, Nicholas J, Sewter, Ciaran P, Digby, Janet E, Mohammed, Shehla N, Hurst, Jane A, Cheetham#, Christopher H, Earley#, Alison R, Barnett, Anthony H, Prins, Johannes B

“…The extreme obesity of the obese (ob/ob) mouse is attributable to mutations in the gene encoding leptin, an adipocyte-specific secreted protein which has…”
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Activators of peroxisome proliferator-activated receptor gamma have depot-specific effects on human preadipocyte differentiation by Adams, M, Montague, C T, Prins, J B, Holder, J C, Smith, S A, Sanders, L, Digby, J E, Sewter, C P, Lazar, M A, Chatterjee, V K, O'Rahilly, S

“…Activation of peroxisome proliferator-activated receptor (PPAR) gamma, a nuclear receptor highly expressed in adipocytes, induces the differentiation of murine…”
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Thiazolidinedione exposure increases the expression of uncoupling protein 1 in cultured human preadipocytes by Digby, J. E., Montague, C. T., Sewter, C. P., Sanders, L., Wilkison, W. O., O'Rahilly, S., Prins, J. B.

“…Thiazolidinedione exposure increases the expression of uncoupling protein 1 in cultured human preadipocytes. J E Digby , C T Montague , C P Sewter , L Sanders…”
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Brachial artery low-flow-mediated constriction is increased early after coronary intervention and reduces during recovery after acute coronary syndrome: characterization of a recently described index of vascular function by SPIRO, Jonathan R, DIGBY, Janet E, GHIMIRE, Gopal, MASON, Mark, MITCHELL, Andrew G, ILSLEY, Charles, DONALD, Ann, DALBY, Miles C. D, KHARBANDA, Rajesh K

“…The endothelium plays a role in regulating vascular tone. Acute and dynamic changes in low-flow-mediated constriction (L-FMC) and how it changes with regard to…”
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The regulation of adiponectin receptors in human prostate cancer cell lines by Mistry, T., Digby, J.E., Chen, J., Desai, K.M., Randeva, H.S.

“…Obesity is a risk factor for prostate cancer, and plasma levels of the adipokine, adiponectin, are low in the former but high in the latter. Adiponectin has…”
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Depot- and sex-specific differences in human leptin mRNA expression: implications for the control of regional fat distribution by MONTAGUE, C. T, PRINS, J. B, SANDERS, L, DIGBY, J. E, O'RAHILLY, S

“…Obese subjects with excess intra-abdominal fat deposition suffer greater adverse metabolic consequences than do similarly overweight subjects with a…”
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Depot-related and thiazolidinedione-responsive expression of uncoupling protein 2 (UCP2) in human adipocytes by Digby, J.E, Crowley, V.E.F, Sewter, C.P, Whitehead, J.P, Prins, J.B, O'Rahilly, S

“…Uncoupling protein 2 (UCP2) is a recently described homologue of the uncoupling protein of brown adipocytes (UCP1), which is expressed at high levels in human…”
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Thiazolidinedione exposure increases the expression of uncoupling protein 1 in cultured human preadipocytes by DIGBY, J. E, MONTAGUE, C. T, SEWTER, C. P, SANDERS, L, WILKISON, W. O, O'RAHILLY, S, PRINS, J. B

“…Thiazolidinediones (TZDs) are a novel class of insulin-sensitizing agents used in the treatment of NIDDM and are potent agonists for the nuclear hormone…”
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The polymerase chain reaction by BAUMFORTH, K. R. N, NELSON, P. N, DIGBY, J. E, O'NEIL, J. D, MURRAY, P. G

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High prevalence of coeliac disease in a population‐based study from Western Australia: a case for screening? by Hovell, Chris J, Collett, Judith A, Vautier, Guy, Cheng, Andy JP, Sutanto, Erica, Mallon, Dominic F, Olynyk, John K, Cullen, Digby JE

“…Objectives To determine the prevalence of coeliac disease in an Australian rural community. Design Retrospective analysis of stored serum samples from 3011…”
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Phonon studies of the fractional quantum Hall effect by Mellor, C.J., Digby, J.E., Eyles, R.H., Kent, A.J., Benedict, K.A., Challis, L.J., Henini, M., Foxon, C.T., Harris, J.J.

“…The energy of the magneto-roton minimum has been measured by non-equilibrium phonon absorption in high mobility electron and hole gases. In the electron gas…”
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Phonon spectroscopy of the fractional quantum Hall effect by Digby, J E, Zeitler, U, Mellor, C J, Kent, A J, Benedict, K A, Henini, M, Foxon, C T, Harris, J J

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Phonon absorption at the magnetoroton minimum in the fractional quantum Hall effect by Mellor, CJ, Eyles, RH, Digby, JE, Kent, AJ, Benedict, KA, Challis, LJ, Henini, M, Foxon, CT, Harris, JJ

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Long-term follow-up of gastric histology after Helicobacter pylori eradication by Forbes, G M, Warren, J R, Glaser, M E, Cullen, D J, Marshall, B J, Collins, B J

“…Helicobacter pylori causes chronic active gastritis and is thought to be associated with the development of gastric atrophy, intestinal metaplasia and…”
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Demystified ... the polymerase chain reaction by Baumforth, K R, Nelson, P N, Digby, J E, O'Neil, J D, Murray, P G

“…Since its initial description over twenty years ago the PCR has become one of the most valuable and flexible tools available to biomedical research…”
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Ballistic phonon absorption in the fractional and non-quantised Hall effects by Zeitler, U., Devitt, A.M., Digby, J.E., Mellor, C.J., Kent, A.J., Benedict, K.A., Cheng, T.

“…We have measured the direct absorption of ballistic phonons by a two-dimensional electron system (2DES) in the fractional quantum Hall regime. We show…”
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