Search Results - "Digby, Elyse M."

An Activatable Photosensitizer Targeting Human NAD(P)H: Quinone Oxidoreductase 1 by Digby, Elyse M., Sadovski, Oleg, Beharry, Andrew A.

“…Human NAD(P)H: Quinone Oxidoreductase 1 (hNQO1) is an attractive enzyme for cancer therapeutics due to its significant overexpression in tumors compared to…”
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Photocaged DNA-Binding Photosensitizer Enables Photocontrol of Nuclear Entry for Dual-Targeted Photodynamic Therapy by Digby, Elyse M., Ayan, Seylan, Shrestha, Pradeep, Gehrmann, Elizabeth J., Winter, Arthur H., Beharry, Andrew A.

“…Photodynamic therapy (PDT) is a clinically approved cancer treatment that requires a photosensitizer (PS), light, and molecular oxygena combination which…”
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Dark Dynamic Therapy: Photosensitization without Light Excitation Using Chemiluminescence Resonance Energy Transfer in a Dioxetane–Erythrosin B Conjugate by Digby, Elyse M., Tung, Matthew T., Kagalwala, Husain N., Ryan, Lucas S., Lippert, Alexander R., Beharry, Andrew A.

“…Reactive oxygen species (e.g., singlet oxygen) are the primary cytotoxic agents used in the clinically approved technique photodynamic therapy (PDT). Although…”
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Correction to “Dark Dynamic Therapy: Photosensitization without Light Excitation Using Chemiluminescence Resonance Energy Transfer in a Dioxetane−Erythrosin B Conjugate” by Digby, Elyse M., Tung, Matthew T., Kagalwala, Husain N., Ryan, Lucas S., Lippert, Alexander R., Beharry, Andrew A.

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Highly Potent Photoinactivation of Bacteria Using a Water-Soluble, Cell-Permeable, DNA-Binding Photosensitizer by Digby, Elyse M, Ma, Tianyi, Zipfel, Warren R, Milstein, Joshua N, Beharry, Andrew A

“…Antimicrobial photodynamic therapy (APDT) employs a photosensitizer, light, and molecular oxygen to treat infectious diseases via oxidative damage, with a low…”
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