Search Results - "Diez, O."
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RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA-mutated breast cancer
Published in Annals of oncology (01-05-2018)“…BRCA1 and BRCA2 (BRCA1/2)-deficient tumors display impaired homologous recombination repair (HRR) and enhanced sensitivity to DNA damaging agents or to…”
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BRCA1 and BRCA2 genetic testing—pitfalls and recommendations for managing variants of uncertain clinical significance
Published in Annals of oncology (01-10-2015)“…Increasing use of BRCA1/2 testing for tailoring cancer treatment and extension of testing to tumour tissue for somatic mutation is moving BRCA1/2 mutation…”
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Palm oil and cardiovascular disease: a randomized trial of the effects of hybrid palm oil supplementation on human plasma lipid patterns
Published in Food & function (01-01-2016)“…This study examines, for the first time, the effect of hybrid Elaeis oleifera × E. guineensis palm oil supplementation on human plasma lipids related to CVD…”
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A New Mathematical Model for the Characterization of Viscosity Variations in the Aqueous Solutions of Monoalcohols and Polyalcohols
Published in Journal of solution chemistry (01-10-2023)“…This study aims to investigate the viscosity of binary mixtures of water with different monoalcohols and polyalcohols. The viscosity values of the mixtures of…”
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Chitosomes as drug delivery systems for C-phycocyanin: Preparation and characterization
Published in International journal of pharmaceutics (15-06-2010)“…The aim of this work was to investigate chitosomes, i.e. liposomes coated by a polyelectrolyte complex between chitosan (CH) and xantan gum (XG), as potential…”
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Design, characterization and in vitro evaluation of 5-aminosalicylic acid loaded N-succinyl-chitosan microparticles for colon specific delivery
Published in Colloids and surfaces, B, Biointerfaces (01-06-2012)“…[Display omitted] ► N-Succinyl-chitosan has proven to exhibit excellent pharmaceutical properties. ► 5-ASA loaded N-succinyl-chitosan microparticles were…”
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BRCA in breast cancer: ESMO Clinical Practice Guidelines
Published in Annals of oncology (01-05-2010)Get full text
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Influence of obesity on plasma lipid and lipoprotein concentrations in dogs
Published in American journal of veterinary research (2005)“…To determine effects of obesity and diet in dogs on plasma lipid and lipoprotein concentrations by assaying plasma leptin and ghrelin concentrations and…”
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Characterization of novel hyaluronic acid matrix systems for vaginal administration of metronidazole
Published in Journal of applied polymer science (15-01-2015)“…ABSTRACT Polymers such as Hyaluronic acid (HA), Polyethylene glycol‐400 (PEG‐400) and Xanthan Gum (XG) are promising in drug delivery applicationsbecause of…”
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BRCA in breast cancer: ESMO Clinical Practice Guidelines
Published in Annals of oncology (01-09-2011)Get full text
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A study of the refractive index and surface tension synergy of the binary water/ethanol: influence of concentration
Published in Physics and chemistry of liquids (01-02-2005)“…Pure alcohols or alcohols mixed with water are the most widely used solvents in a great variety of industrial applications, including the formulation of…”
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Stochastic resonance in human electroencephalographic activity elicited by mechanical tactile stimuli
Published in Neuroscience letters (24-05-2002)“…Stochastic resonance (SR) is a phenomenon in which the response of a non-linear system to a weak input signal is optimized by the presence of noise. The aim of…”
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Rheological properties of progesterone microemulsions: Influence of xanthan and chitosan biopolymer concentration
Published in Journal of applied polymer science (15-10-2008)“…In this preformulations study, rheological properties of microemulsions with progesterone (1%) were studied to analyze the effect of xanthan and chitosan at…”
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Classification of missense variants of unknown significance in BRCA1 based on clinical and tumor information
Published in Human mutation (01-05-2007)“…Classification of rare missense variants in disease susceptibility genes as neutral or disease‐causing is important for genetic counseling. Different criteria…”
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Rheological characterization of chitosan matrices: Influence of biopolymer concentration
Published in Journal of applied polymer science (15-08-2007)“…Viscoelastic properties of chitosan (CH), chitosan‐poly(ethylene glycol) 400 (CH‐PEG), and chitosan‐poly(ethylene glycol) 400 with glyoxal as crosslinking…”
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Germline ATM mutational analysis in BRCA1/BRCA2 negative hereditary breast cancer families by MALDI-TOF mass spectrometry
Published in Breast cancer research and treatment (01-07-2011)“…Biallelic inactivation of ATM gene causes the rare autosomal recessive disorder Ataxia-telangiectasia (A-T). Female relatives of A-T patients have a two-fold…”
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A solid-phase extraction and size-exclusion liquid chromatographic method for polyethylene glycol 25 p-aminobenzoic acid determination in urine: Validation for urinary excretion studies of users of sunscreens
Published in Analytica chimica acta (24-03-2008)“…No previous publications about percutaneous absorption of polyethylene glycol 25 p-aminobenzoic acid (PEG-25 PABA) have been found in the literature and the…”
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Rheological study and thermodynamic analysis of the binary system (water/ethanol): Influence of concentration
Published in Physics and chemistry of liquids (01-10-2004)“…Water is the most widely used solvent in the chemical and pharmaceutical industry, since it is the most physiological and best tolerated excipient. However, in…”
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Acyclovir delivery matrices based on poly(ethylene glycol)/chitosan semi-interpenetrating networks
Published in Journal of pharmaceutical sciences (01-06-2007)“…Chitosan matrix systems have been studied as potential vehicles for the prolonged release of acyclovir (ACV). The influence of chitosan concentration (from…”
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