Search Results - "Dietze, Eric C."

Triple-negative breast cancer in African-American women: disparities versus biology by Dietze, Eric C., Sistrunk, Christopher, Miranda-Carboni, Gustavo, O'Regan, Ruth, Seewaldt, Victoria L.

“…There is evidence that African-American women with triple-negative breast cancer (TNBC) have worse clinical outcomes than women of European descent with TNBC…”
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Metabolic Health, Insulin, and Breast Cancer: Why Oncologists Should Care About Insulin by Yee, Lisa D, Mortimer, Joanne E, Natarajan, Rama, Dietze, Eric C, Seewaldt, Victoria L

“…Studies investigating the potential link between adult pre-menopausal obesity [as measured by body mass index (BMI)] and triple-negative breast cancer have…”
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Impact of Federal, State, and Local Housing Policies on Disparities in Cardiovascular Disease in Black/African American Men and Women: From Policy to Pathways to Biology by Sistrunk, Christopher, Tolbert, Nora, Sanchez-Pino, Maria Dulfary, Erhunmwunsee, Loretta, Wright, Nikita, Jones, Veronica, Hyslop, Terry, Miranda-Carboni, Gustavo, Dietze, Eric C, Martinez, Ernest, George, Sophia, Ochoa, Augusto C, Winn, Robert A, Seewaldt, Victoria L

“…Racist and discriminatory federal, state, and local housing policies significantly contribute to disparities in cardiovascular disease incidence and mortality…”
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Metformin and Chemoprevention: Potential for Heart-Healthy Targeting of Biologically Aggressive Breast Cancer by Jones, Veronica C, Dietze, Eric C, Jovanovic-Talisman, Tijana, McCune, Jeannine S, Seewaldt, Victoria L

“…Currently, tamoxifen is the only drug approved for reduction of breast cancer risk in premenopausal women. The significant cardiovascular side effects of…”
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Obesity and Triple-Negative Breast Cancer: Disparities, Controversies, and Biology by Dietze, Eric C, Chavez, Tanya A, Seewaldt, Victoria L

“…Once considered a problem of Western nations, obesity (body mass index ≥30 kg/m ) has rapidly increased since the 1970s to become a major threat to world…”
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CpG Island Tumor Suppressor Promoter Methylation in Non-BRCA-Associated Early Mammary Carcinogenesis by VASILATOS, Shauna N, BROADWATER, Gloria, SKAAR, David, PAISIE, Carolyn, TORRES-HERNANDEZ, Alejandro, GRANT, Tracey L, WILKE, Lee G, IBARRA-DRENDALL, Catherine, OSTRANDER, Julie H, D'AMATO, Nicholas C, ZALLES, Carola, JIRTLE, Randy, BARRY, William T, WEAVER, Valerie M, SEEWALDT, Victoria L, BAKER, Joseph C, LEM, Siya, DIETZE, Eric C, BEAN, Gregory R, BRYSON, Andrew D, PILIE, Patrick G, GOLDENBERG, Vanessa

“…Background: Only 5% of all breast cancers are the result of BRCA1/2 mutations. Methylation silencing of tumor suppressor genes is well described in sporadic…”
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Environmental Exposures during Puberty: Window of Breast Cancer Risk and Epigenetic Damage by Natarajan, Rama, Aljaber, Dana, Au, Dawn, Thai, Christine, Sanchez, Angelica, Nunez, Alan, Resto, Cristal, Chavez, Tanya, Jankowska, Marta M, Benmarhnia, Tarik, Yang, Jiue-An, Jones, Veronica, Tomsic, Jerneja, McCune, Jeannine S, Sistrunk, Christopher, Doan, Stacey, Serrano, Mayra, Cardiff, Robert D, Dietze, Eric C, Seewaldt, Victoria L

“…During puberty, a woman's breasts are vulnerable to environmental damage ("window of vulnerability"). Early exposure to environmental carcinogens, endocrine…”
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Insulin Resistance in Women Correlates with Chromatin Histone Lysine Acetylation, Inflammatory Signaling, and Accelerated Aging by Vidal, Christina M, Alva-Ornelas, Jackelyn A, Chen, Nancy Zhuo, Senapati, Parijat, Tomsic, Jerneja, Robles, Vanessa Myriam, Resto, Cristal, Sanchez, Nancy, Sanchez, Angelica, Hyslop, Terry, Emwas, Nour, Aljaber, Dana, Bachelder, Nick, Martinez, Ernest, Ann, David, Jones, Veronica, Winn, Robert A, Miele, Lucio, Ochoa, Augusto C, Dietze, Eric C, Natarajan, Rama, Schones, Dustin, Seewaldt, Victoria L

“…Epigenetic changes link medical, social, and environmental factors with cardiovascular and kidney disease and, more recently, with cancer. The mechanistic link…”
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Epigenetic Dysregulation of KCNK9 Imprinting and Triple-Negative Breast Cancer by Skaar, David A, Dietze, Eric C, Alva-Ornelas, Jackelyn A, Ann, David, Schones, Dustin E, Hyslop, Terry, Sistrunk, Christopher, Zalles, Carola, Ambrose, Adrian, Kennedy, Kendall, Idassi, Ombeni, Miranda Carboni, Gustavo, Gould, Michael N, Jirtle, Randy L, Seewaldt, Victoria L

“…Genomic imprinting is an inherited form of parent-of-origin specific epigenetic gene regulation that is dysregulated by poor prenatal nutrition and…”
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Suppression of p53 Function in Normal Human Mammary Epithelial Cells Increases Sensitivity to Extracellular Matrix-Induced Apoptosis by Seewaldt, Victoria L., Mrózek, Krzysztof, Sigle, Randy, Dietze, Eric C., Heine, Kevin, Hockenbery, David M., Hobbs, Katherine B., Caldwell, L. Elizabeth

“…Little is known about the fate of normal human mammary epithelial cells (HMECs) that lose p53 function in the context of extracellular matrix (ECM)-derived…”
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Spatiotemporal strategies to identify aggressive biology in precancerous breast biopsies by Frankhauser, David E., Jovanovic‐Talisman, Tijana, Lai, Lily, Yee, Lisa D., Wang, Lihong V., Mahabal, Ashish, Geradts, Joseph, Rockne, Russell C., Tomsic, Jerneja, Jones, Veronica, Sistrunk, Christopher, Miranda‐Carboni, Gustavo, Dietze, Eric C., Erhunmwunsee, Loretta, Hyslop, Terry, Seewaldt, Victoria L.

“…Over 90% of breast cancer is cured; yet there remain highly aggressive breast cancers that develop rapidly and are extremely difficult to treat, much less…”
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Mammographic Density: Intersection of Advocacy, Science, and Clinical Practice by Tossas-Milligan, Katherine, Shalabi, Sundus, Jones, Veronica, Keely, Patricia J., Conklin, Matthew W., Eliceiri, Kevin W., Winn, Robert, Sistrunk, Christopher, Geradts, Joseph, Miranda-Carboni, Gustavo A., Dietze, Eric C., Yee, Lisa D., Seewaldt, Victoria L.

“…Purpose of Review Here we aim to review the association between mammographic density, collagen structure, and breast cancer risk. Recent Findings While…”
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Purification and characterization of recombinant CH3 domain fragment of the CREB-binding protein by Drendall, Catherine Ibarra, Pham, Quang H., Dietze, Eric C.

“…CREB-binding protein (CBP) is an important coactivator of basal transcription machinery and a critical regulator of cellular proliferation, differentiation,…”
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Metabolic Syndrome and Breast Cancer Risk: Is There a Role for Metformin? by Ibarra-Drendall, Catherine, Dietze, Eric C., Seewaldt, Victoria L.

“…Obesity is one of the most important known preventable causes of cancer, accounting for up to 20% of cancer deaths in women. Obese women have increased risk of…”
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Interferon-regulatory factor-1 is critical for tamoxifen-mediated apoptosis in human mammary epithelial cells by BOWIE, Michelle L, DIETZE, Eric C, DELROW, Jeffery, BEAN, Gregory R, TROCH, Michelle M, MARJORAM, Robin J, SEEWALDT, Victoria L

“…Unlike estrogen receptor-positive (ER(+)) breast cancers, normal human mammary epithelial cells (HMECs) typically express low nuclear levels of ER (ER poor)…”
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Tamoxifen but Not 4-Hydroxytamoxifen Initiates Apoptosis in p53(−) Normal Human Mammary Epithelial Cells by Inducing Mitochondrial Depolarization by Dietze, Eric C., Caldwell, L. Elizabeth, Grupin, Svetlana L., Mancini, Mariangela, Seewaldt, Victoria L.

“…Despite the widespread clinical use of tamoxifen as a breast cancer prevention agent, the molecular mechanism of tamoxifen chemoprevention is poorly…”
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CREB-binding protein regulates apoptosis and growth of HMECs grown in reconstituted ECM via laminin-5 by Dietze, Eric C, Bowie, Michelle L, Mrózek, Krzysztof, Caldwell, L Elizabeth, Neal, Cassandra, Marjoram, Robin J, Troch, Michelle M, Bean, Gregory R, Yokoyama, Kazunari K, Ibarra, Catherine A, Seewaldt, Victoria L

“…Interactions between normal mammary epithelial cells and extracellular matrix (ECM) are important for mammary gland homeostasis. Loss of interactions between…”
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CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells by Dietze, Eric C, Troch, Michelle M, Bowie, Michelle L, Yee, Lisa, Bean, Gregory R, Seewaldt, Victoria L

“…The coactivators CBP and p300 are recruited by retinoic acid receptors (RARs) during retinoid mediated transcriptional regulation. To assess the role of…”
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Re: Active Tamoxifen Metabolite Plasma Concentrations After Coadministration of Tamoxifen and the Selective Serotonin Reuptake Inhibitor Paroxetine by Ponzone, Riccardo, Biglia, Nicoletta, Sismondi, Piero

“…J Natl Cancer Inst 2003;95:1758 64.(2) Early Breast Cancer Trialists CollaborativeGroup. Tamoxifen for early breast cancer: anoverview of the randomised…”
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Tamoxifen and tamoxifen ethyl bromide induce apoptosis in acutely damaged mammary epithelial cells through modulation of AKT activity by DIETZE, Eric C, TROCH, Michelle M, BEAN, Gregory R, HEFFNER, Joshua B, BOWIE, Michelle L, ROSENBERG, Paul, RATLIFF, Brooke, SEEWALDT, Victoria L

“…Normal human mammary epithelial cells (HMECs), unlike estrogen receptor-positive (ER+) breast cancers, typically express low nuclear levels of ER (ER-'poor')…”
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