Search Results - "Dietz, Robert M."

Circulating heparan sulfate fragments mediate septic cognitive dysfunction by Hippensteel, Joseph A, Anderson, Brian J, Orfila, James E, McMurtry, Sarah A, Dietz, Robert M, Su, Guowei, Ford, Joshay A, Oshima, Kaori, Yang, Yimu, Zhang, Fuming, Han, Xiaorui, Yu, Yanlei, Liu, Jian, Linhardt, Robert J, Meyer, Nuala J, Herson, Paco S, Schmidt, Eric P

“…Septic patients frequently develop cognitive impairment that persists beyond hospital discharge. The impact of sepsis on electrophysiological and molecular…”
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Extended therapeutic window of a novel peptide inhibitor of TRPM2 channels following focal cerebral ischemia by Shimizu, Takeru, Dietz, Robert M., Cruz-Torres, Ivelisse, Strnad, Frank, Garske, Ana K., Moreno, Myriam, Venna, Venugopal R., Quillinan, Nidia, Herson, Paco S.

“…TRPM2 channels have been suggested to play a role in ischemic neuronal injury, specifically in males. A major hindrance to TRPM2 research has been the lack of…”
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Differences in hippocampal plasticity and memory outcomes in anterior versus posterior cerebellar stroke by Moreno, Myriam, Minjarez, Crystal, Vigil, Jose, Orfila, James E., Schmidt, Roxanna, Burch, Amelia, Carter, Danelle J., Kubesh, Molly, Yonchek, Joan, Dietz, Robert M., Quillinan, Nidia

“…Neurological symptoms following cerebellar stroke can range from motor to cognitive-affective impairments. Topographic imaging studies from patients with…”
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Neonates Hospitalized with Community-Acquired SARS-CoV-2 in a Colorado Neonatal Intensive Care Unit by White, Alicia, Mukherjee, Priya, Stremming, Jane, Sherlock, Laura G, Reynolds, Regina M, Smith, Danielle, Asturias, Edwin J, Grover, Theresa R, Dietz, Robert M

“…The novel coronavirus 2019 (SARS-CoV-2) has been well described in adults. Further, the impact on older children and during the perinatal time is becoming…”
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Delayed inhibition of tonic inhibition enhances functional recovery following experimental ischemic stroke by Orfila, James E, Grewal, Himmat, Dietz, Robert M, Strnad, Frank, Shimizu, Takeru, Moreno, Myriam, Schroeder, Christian, Yonchek, Joan, Rodgers, Krista M, Dingman, Andra, Bernard, Timothy J, Quillinan, Nidia, Macklin, Wendy B, Traystman, Richard J, Herson, Paco S

“…The current study focuses on the ability to improve cognitive function after stroke with interventions administered at delayed/chronic time points. In light of…”
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Autonomous CaMKII Activity as a Drug Target for Histological and Functional Neuroprotection after Resuscitation from Cardiac Arrest by Deng, Guiying, Orfila, James E., Dietz, Robert M., Moreno-Garcia, Myriam, Rodgers, Krista M., Coultrap, Steve J., Quillinan, Nidia, Traystman, Richard J., Bayer, K. Ulrich, Herson, Paco S.

“…The Ca2+/calmodulin-dependent protein kinase II (CaMKII) is a major mediator of physiological glutamate signaling, but its role in pathological glutamate…”
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Zn2+ Influx Is Critical for Some Forms of Spreading Depression in Brain Slices by Dietz, Robert M, Weiss, John H, Shuttleworth, Claude W

“…Spreading depression (SD) is wave of profound depolarization that propagates throughout brain tissue and can contribute to the spread of injury after stroke or…”
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Mild myelin disruption elicits early alteration in behavior and proliferation in the subventricular zone by Gould, Elizabeth A, Busquet, Nicolas, Shepherd, Douglas, Dietz, Robert M, Herson, Paco S, Simoes de Souza, Fabio M, Li, Anan, George, Nicholas M, Restrepo, Diego, Macklin, Wendy B

“…Myelin, the insulating sheath around axons, supports axon function. An important question is the impact of mild myelin disruption. In the absence of the myelin…”
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Functional Restoration following Global Cerebral Ischemia in Juvenile Mice following Inhibition of Transient Receptor Potential M2 (TRPM2) Ion Channels by Dietz, Robert M., Orfila, James E., Chalmers, Nicholas, Minjarez, Crystal, Vigil, Jose, Deng, Guying, Quillinan, Nidia, Herson, Paco S.

“…Hippocampal cell death and cognitive dysfunction are common following global cerebral ischemia across all ages, including children. Most research has focused…”
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Neonatal Ketamine Alters High-Frequency Oscillations and Synaptic Plasticity in the Subiculum But Does not Affect Sleep Macrostructure in Adolescent Rats by Manzella, Francesca M, Joksimovic, Srdjan M, Orfila, James E, Fine, Brier R, Dietz, Robert M, Sampath, Dayalan, Fiedler, Hanna K, Tesic, Vesna, Atluri, Navya, Raol, Yogendra H, Jevtovic-Todorovic, Vesna, Herson, Paco S, Todorovic, Slobodan M

“…Exposure to sedative/hypnotic and anesthetic drugs, such as ketamine, during the critical period of synaptogenesis, causes profound neurotoxicity in the…”
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Cardiac Arrest Induces Ischemic Long-Term Potentiation of Hippocampal CA1 Neurons That Occludes Physiological Long-Term Potentiation by Quillinan, Nidia, Dietz, Robert M., Chalmers, Nicholas, Deng, Guiying, Moreno, Myriam, McKinnon, Nicole, Orfila, James E., Herson, Paco S.

“…Ischemic long-term potentiation (iLTP) is a form of synaptic plasticity that occurs in acute brain slices following oxygen-glucose deprivation. In vitro, iLTP…”
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Cerebral ischemia in the developing brain by Dietz, Robert M, Dingman, Andra L, Herson, Paco S

“…Brain ischemia affects all ages, from neonates to the elderly population, and is a leading cause of mortality and morbidity. Multiple preclinical rodent models…”
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Neonatal cardiopulmonary resuscitation: is ROSC enough? by Dietz, Robert M., Gonzalez, Fernando F.

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An Unusual Presentation of Dermatophytosis in a Premature Infant by Dietz, Robert M., MD, PhD, Stewart, Michael S., MD, Fuller, Erin N., MD, Paugh, Holly C., MD, Morelli, Joseph G., MD, Wright, Rachel, MD

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Abdominal Radiograph with Intravesical Air and Possible Small Bowel Atresia by Stewart, Michael S., MD, Dietz, Robert M., MD, PhD, Landman, Matthew P., MD, MPH, Moulton, Steven L., MD, Wright, Clyde J., MD

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Nasal high‐flow therapy for Newborn infants in special care nurseries by Stein, Yin, Dietz, Robert M.

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Oxidative stress diseases unique to the perinatal period: A window into the developing innate immune response by Dietz, Robert M., Wright, Clyde J.

“…The innate immune system has evolved to play an integral role in the normally developing lung and brain. However, in response to oxidative stress, innate…”
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Potential Adjuncts to Therapeutic Hypothermia to Mitigate Multiorgan Injury in Perinatal Hypoxia-Ischemia by Turner, Megan J., Dietz, Robert M.

“…Over the last 2 decades, therapeutic hypothermia has become the standard of care to reduce morbidity and mortality in neonates affected by moderate-to-severe…”
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Experimental pediatric stroke shows age-specific recovery of cognition and role of hippocampal Nogo-A receptor signaling by Orfila, James E, Dietz, Robert M, Rodgers, Krista M, Dingman, Andra, Patsos, Olivia P, Cruz-Torres, Ivelisse, Grewal, Himmat, Strnad, Frank, Schroeder, Christian, Herson, Paco S

“…Ischemic stroke is a leading cause of death worldwide and clinical data suggest that children may recover from stroke better than adults; however, supporting…”
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Late initiation of therapeutic hypothermia: not the new standard of care by Bourque, Stephanie L., Dietz, Robert M.

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