Search Results - "Dietrich, Melanie"

Humoral and circulating follicular helper T cell responses in recovered patients with COVID-19 by Juno, Jennifer A., Tan, Hyon-Xhi, Lee, Wen Shi, Reynaldi, Arnold, Kelly, Hannah G., Wragg, Kathleen, Esterbauer, Robyn, Kent, Helen E., Batten, C. Jane, Mordant, Francesca L., Gherardin, Nicholas A., Pymm, Phillip, Dietrich, Melanie H., Scott, Nichollas E., Tham, Wai-Hong, Godfrey, Dale I., Subbarao, Kanta, Davenport, Miles P., Kent, Stephen J., Wheatley, Adam K.

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has dramatically expedited global vaccine development efforts 1 – 3 , most targeting…”
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The bulky and the sweet: How neutralizing antibodies and glycan receptors compete for virus binding by Dietrich, Melanie H., Harprecht, Christina, Stehle, Thilo

“…Numerous viruses rely on glycan receptor binding as the initial step in host cell infection. Engagement of specific glycan receptors such as sialylated…”
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Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice by Pymm, Phillip, Adair, Amy, Chan, Li-Jin, Cooney, James P., Mordant, Francesca L., Allison, Cody C., Lopez, Ester, Haycroft, Ebene R., O’Neill, Matthew T., Tan, Li Lynn, Dietrich, Melanie H., Drew, Damien, Doerflinger, Marcel, Dengler, Michael A., Scott, Nichollas E., Wheatley, Adam K., Gherardin, Nicholas A., Venugopal, Hariprasad, Cromer, Deborah, Davenport, Miles P., Pickering, Raelene, Godfrey, Dale I., Purcell, Damian F. J., Kent, Stephen J., Chung, Amy W., Subbarao, Kanta, Pellegrini, Marc, Glukhova, Alisa, Tham, Wai-Hong

“…Neutralizing antibodies are important for immunity against SARS-CoV-2 and as therapeutics for the prevention and treatment of COVID-19. Here, we identified…”
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Plasmodium vivax Reticulocyte Binding Proteins for invasion into reticulocytes by Chan, Li‐Jin, Dietrich, Melanie H., Nguitragool, Wang, Tham, Wai‐Hong

“…Plasmodium vivax is responsible for most of the malaria infections outside Africa and is currently the predominant malaria parasite in countries under…”
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Reovirus Neurotropism and Virulence Are Dictated by Sequences in the Head Domain of the Viral Attachment Protein by Sutherland, Danica M, Aravamudhan, Pavithra, Dietrich, Melanie H, Stehle, Thilo, Dermody, Terence S

“…Viral capsid components that bind cellular receptors mediate critical functions in viral tropism and disease pathogenesis. Mammalian orthoreoviruses…”
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Structural and Functional Features of the Reovirus σ1 Tail by Dietrich, Melanie H, Ogden, Kristen M, Long, Jacob M, Ebenhoch, Rebecca, Thor, Alexandra, Dermody, Terence S, Stehle, Thilo

“…Mammalian orthoreovirus attachment to target cells is mediated by the outer capsid protein σ1, which projects from the virion surface. The σ1 protein is a…”
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Nanobodies against Pfs230 block Plasmodium falciparum transmission by Dietrich, Melanie H, Gabriela, Mikha, Reaksudsan, Kitsanapong, Dixon, Matthew W A, Chan, Li-Jin, Adair, Amy, Trickey, Stephanie, O'Neill, Matthew T, Tan, Li Lynn, Lopaticki, Sash, Healer, Julie, Keremane, Sravya, Cowman, Alan F, Tham, Wai-Hong

“…Transmission blocking interventions can stop malaria parasite transmission from mosquito to human by inhibiting parasite infection in mosquitos. One of the…”
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Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b by Chan, Li-Jin, Gandhirajan, Anugraha, Carias, Lenore L, Dietrich, Melanie H, Vadas, Oscar, Visentin, Remy, França, Camila T, Menant, Sebastien, Soldati-Favre, Dominique, Mueller, Ivo, King, Christopher L, Tham, Wai-Hong

“…Plasmodium vivax preferentially invades reticulocytes and recognition of these cells is mediated by P. vivax Reticulocyte Binding Protein 2b (PvRBP2b) binding…”
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Plasmodium 6-Cysteine Proteins: Functional Diversity, Transmission-Blocking Antibodies and Structural Scaffolds by Lyons, Frankie M T, Gabriela, Mikha, Tham, Wai-Hong, Dietrich, Melanie H

“…The 6-cysteine protein family is one of the most abundant surface antigens that are expressed throughout the   life cycle. Many members of the 6-cysteine…”
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Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax by Hodder, Anthony N, Christensen, Janni, Scally, Stephen, Triglia, Tony, Ngo, Anna, Birkinshaw, Richard W, Bailey, Brodie, Favuzza, Paola, Dietrich, Melanie H, Tham, Wai-Hong, Czabotar, Peter E, Lowes, Kym, Guo, Zhuyan, Murgolo, Nicholas, Lera Ruiz, Manuel de, McCauley, John A, Sleebs, Brad E, Olsen, David, Cowman, Alan F

“…Plasmepsins IX (PMIX) and X (PMX) are essential aspartyl proteases for Plasmodium spp. egress, invasion, and development. WM4 and WM382 inhibit PMIX and PMX in…”
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Comparison of total immunoglobulin G antibody responses to different protein fragments of Plasmodium vivax Reticulocyte binding protein 2b by Bourke, Caitlin, Takashima, Eizo, Chan, Li-Jin, Dietrich, Melanie H, Mazhari, Ramin, White, Michael, Sattabongkot, Jetsumon, Tham, Wai-Hong, Tsuboi, Takafumi, Mueller, Ivo, Longley, Rhea

“…Plasmodium vivax is emerging as the dominant and prevalent species causing malaria in near-elimination settings outside of Africa. Hypnozoites, the dormant…”
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Structure of Serotype 1 Reovirus Attachment Protein sigma 1 in Complex with Junctional Adhesion Molecule A Reveals a Conserved Serotype-Independent Binding Epitope by Stettner, Eva, Dietrich, Melanie H, Reiss, Kerstin, Dermody, Terence S, Stehle, Thilo

“…Mammalian orthoreoviruses use glycans and junctional adhesion molecule A (JAM-A) as attachment receptors. We determined the structure of serotype 1 reovirus…”
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Structure of Serotype 1 Reovirus Attachment Protein σ1 in Complex with Junctional Adhesion Molecule A Reveals a Conserved Serotype-Independent Binding Epitope by Stettner, Eva, Dietrich, Melanie H, Reiss, Kerstin, Dermody, Terence S, Stehle, Thilo

“…Mammalian orthoreoviruses use glycans and junctional adhesion molecule A (JAM-A) as attachment receptors. We determined the structure of serotype 1 reovirus…”
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Naturally acquired blocking human monoclonal antibodies to Plasmodiumvivax reticulocyte binding protein 2b by Chan, Li-Jin, Gandhirajan, Anugraha, Carias, Lenore L., Dietrich, Melanie H., Vadas, Oscar, Visentin, Remy, França, Camila T., Menant, Sebastien, Soldati-Favre, Dominique, Mueller, Ivo, King, Christopher L., Tham, Wai-Hong

“…Plasmodium vivax preferentially invades reticulocytes and recognition of these cells is mediated by P. vivax Reticulocyte Binding Protein 2b (PvRBP2b) binding…”
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Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain by Wheatley, Adam K., Pymm, Phillip, Esterbauer, Robyn, Dietrich, Melanie H., Lee, Wen Shi, Drew, Damien, Kelly, Hannah G., Chan, Li-Jin, Mordant, Francesca L., Black, Katrina A., Adair, Amy, Tan, Hyon-Xhi, Juno, Jennifer A., Wragg, Kathleen M., Amarasena, Thakshila, Lopez, Ester, Selva, Kevin J., Haycroft, Ebene R., Cooney, James P., Venugopal, Hariprasad, Tan, Li Lynn, O Neill, Matthew T., Allison, Cody C., Cromer, Deborah, Davenport, Miles P., Bowen, Richard A., Chung, Amy W., Pellegrini, Marc, Liddament, Mark T., Glukhova, Alisa, Subbarao, Kanta, Kent, Stephen J., Tham, Wai-Hong

“…Potent neutralizing monoclonal antibodies are one of the few agents currently available to treat COVID-19. SARS-CoV-2 variants of concern (VOCs) that carry…”
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Structural Insights into Reovirus σ1 Interactions with Two Neutralizing Antibodies by Dietrich, Melanie H, Ogden, Kristen M, Katen, Sarah P, Reiss, Kerstin, Sutherland, Danica M, Carnahan, Robert H, Goff, Matthew, Cooper, Tracy, Dermody, Terence S, Stehle, Thilo

“…Reovirus attachment protein σ1 engages glycan receptors and junctional adhesion molecule-A (JAM-A) and is thought to undergo a conformational change during the…”
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Structural Insights into Reovirus sigma 1 Interactions with Two Neutralizing Antibodies by Dietrich, Melanie H, Ogden, Kristen M, Katen, Sarah P, Reiss, Kerstin, Sutherland, Danica M, Carnahan, Robert H, Goff, Matthew, Cooper, Tracy, Dermody, Terence S, Stehle, Thilo

“…Reovirus attachment protein sigma 1 engages glycan receptors and junctional adhesion molecule-A (JAM-A) and is thought to undergo a conformational change…”
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Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle by Favuzza, Paola, de Lera Ruiz, Manuel, Thompson, Jennifer K., Triglia, Tony, Ngo, Anna, Steel, Ryan W.J., Vavrek, Marissa, Christensen, Janni, Healer, Julie, Boyce, Christopher, Guo, Zhuyan, Hu, Mengwei, Khan, Tanweer, Murgolo, Nicholas, Zhao, Lianyun, Penington, Jocelyn Sietsma, Reaksudsan, Kitsanapong, Jarman, Kate, Dietrich, Melanie H., Richardson, Lachlan, Guo, Kai-Yuan, Lopaticki, Sash, Tham, Wai-Hong, Rottmann, Matthias, Papenfuss, Tony, Robbins, Jonathan A., Boddey, Justin A., Sleebs, Brad E., Sabroux, Hélène Jousset, McCauley, John A., Olsen, David B., Cowman, Alan F.

“…Artemisin combination therapy (ACT) is the main treatment option for malaria, which is caused by the intracellular parasite Plasmodium. However, increased…”
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Structure of the Pf12 and Pf41 heterodimeric complex of Plasmodium falciparum 6-cysteine proteins by Dietrich, Melanie H, Chan, Li-Jin, Adair, Amy, Boulet, Coralie, O'Neill, Matthew T, Tan, Li Lynn, Keremane, Sravya, Mok, Yee-Foong, Lo, Alvin W, Gilson, Paul, Tham, Wai-Hong

“…Abstract During the different stages of the Plasmodium life cycle, surface-associated proteins establish key interactions with the host and play critical roles…”
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The usefulness of Enhanced Recovery After Surgery concepts for colorectal resections: an economic analysis under DRG conditions by Koch, Franziska, Green, Martina, Dietrich, Melanie, Moikow, Lutz, Schmidt, Mareike, Ristig, Matthias, Meier-Hellmann, Andreas, Ritz, Jörg-Peter

“…Purpose ERAS® (Enhanced Recovery After Surgery) describes a multimodal, interdisciplinary, and interprofessional treatment concept that optimizes the…”
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