Search Results - "Dietl, Alexander"

Comparative Analysis of Mitochondria Surrounding the Intercalated Discs in Heart Diseases-An Ultrastructural Pilot Study by Schönmehl, Rebecca, Mendelsohn, Daniel H, Winter, Lina, Pabel, Steffen, Niedermair, Tanja, Evert, Katja, Cheung, Wing-Hoi, Wong, Ronald Man Yeung, Schmitt, Volker H, Keller, Karsten, Barsch, Friedrich, Dietl, Alexander, Gummert, Jan F, Schramm, René, Sossalla, Samuel, Brochhausen, Christoph

“…Mitochondria play a crucial role in adapting to fluctuating energy demands, particularly in various heart diseases. This study investigates mitochondrial…”
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NT-proBNP Predicts Cardiovascular Death in the General Population Independent of Left Ventricular Mass and Function: Insights from a Large Population-Based Study with Long-Term Follow-Up by Dietl, Alexander, Stark, Klaus, Zimmermann, Martina E, Meisinger, Christa, Schunkert, Heribert, Birner, Christoph, Maier, Lars S, Peters, Annette, Heid, Iris M, Luchner, Andreas

“…B-type natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) predict cardiovascular endpoints in patients and all-cause death in the general population…”
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Changes in healthcare seeking and lifestyle in old aged individuals during COVID-19 lockdown in Germany: the population-based AugUR study by Brandl, Caroline, Zimmermann, Martina E, Günther, Felix, Dietl, Alexander, Küchenhoff, Helmut, Loss, Julika, Stark, Klaus J, Heid, Iris M

“…Containment measures in the COVID-19 pandemic protected individuals at high risk, particularly individuals at old age, but little is known about how these…”
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Skeletal muscle alterations in tachycardia-induced heart failure are linked to deficient natriuretic peptide signalling and are attenuated by RAS-/NEP-inhibition by Dietl, Alexander, Winkel, Ingrid, Pietrzyk, Gabriela, Paulus, Michael, Bruckmann, Astrid, Schröder, Josef A, Sossalla, Samuel, Luchner, Andreas, Maier, Lars S, Birner, Christoph

“…Heart failure induced cachexia is highly prevalent. Insights into disease progression are lacking. Early state of left ventricular dysfunction (ELVD) and…”
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Distribution and specificity of high-sensitivity cardiac troponin T in older adults without acute cardiac conditions: cross-sectional results from the population-based AugUR study by Dietl, Alexander, Zimmermann, Martina E, Brandl, Caroline, Wallner, Stefan, Burkhardt, Ralph, Maier, Lars S, Luchner, Andreas, Heid, Iris M, Stark, Klaus J

“…ObjectiveEuropean guidelines recommended a uniform upper reference limit of high-sensitivity cardiac troponin T (hsTnT) to rule out non-ST segment elevation…”
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Combined Inhibition of the Renin-Angiotensin System and Neprilysin Positively Influences Complex Mitochondrial Adaptations in Progressive Experimental Heart Failure by Grois, Laura, Hupf, Julian, Reinders, Jörg, Schröder, Josef, Dietl, Alexander, Schmid, Peter M, Jungbauer, Carsten, Resch, Markus, Maier, Lars S, Luchner, Andreas, Birner, Christoph

“…Inhibitors of the renin angiotensin system and neprilysin (RAS-/NEP-inhibitors) proved to be extraordinarily beneficial in systolic heart failure. Furthermore,…”
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3D vena contracta area after MitraClip© procedure: precise quantification of residual mitral regurgitation and identification of prognostic information by Dietl, Alexander, Prieschenk, Christine, Eckert, Franziska, Birner, Christoph, Luchner, Andreas, Maier, Lars S, Buchner, Stefan

“…Percutaneous mitral valve repair (PMVR) is increasingly performed in patients with severe mitral regurgitation (MR). Post-procedural MR grading is challenging…”
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Cardiac unloading by LVAD support differentially influences components of the cGMP–PKG signaling pathway in ischemic and dilated cardiomyopathy by Persoon, Sven, Paulus, Michael, Hirt, Stephan, Jungbauer, Carsten, Dietl, Alexander, Luchner, Andreas, Schmid, Christof, Maier, Lars S., Birner, Christoph

“…Implantation of left ventricular assist devices (LVADs) as bridge to transplant in end-stage heart failure allows for analyzing reverse remodeling processes of…”
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Experimental Heart Failure Induces Alterations of the Lung Proteome - Insight into Molecular Mechanisms by Birner, Christoph, Hierl, Sarah, Dietl, Alexander, Hupf, Julian, Jungbauer, Carsten, Schmid, Peter M., Rümmele, Petra, Deutzmann, Rainer, Riegger, Günter, Luchner, Andreas

“…Background: Heart failure (CHF) is characterized by dyspnea and pulmonary changes. The underlying molecular adaptations are unclear, but might provide targets…”
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Targeting Mitochondrial Calcium Handling and Reactive Oxygen Species in Heart Failure by Dietl, Alexander, Maack, Christoph

“…Purpose of Review In highly prevalent cardiac diseases, new therapeutic approaches are needed. Since the first description of oxidative stress in heart…”
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Regulation of titin-based cardiac stiffness by unfolded domain oxidation (UnDOx) by Loescher, Christine M., Breitkreuz, Martin, Li, Yong, Nickel, Alexander, Unger, Andreas, Dietl, Alexander, Schmidt, Andreas, Mohamed, Belal A., Kötter, Sebastian, Schmitt, Joachim P., Krüger, Marcus, Krüger, Martina, Toischer, Karl, Maack, Christoph, Leichert, Lars I., Hamdani, Nazha, Linke, Wolfgang A.

“…The relationship between oxidative stress and cardiac stiffness is thought to involve modifications to the giant muscle protein titin, which in turn can…”
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Metabolic imbalance of T cells in COVID-19 is hallmarked by basigin and mitigated by dexamethasone by Siska, Peter J, Decking, Sonja-Maria, Babl, Nathalie, Matos, Carina, Bruss, Christina, Singer, Katrin, Klitzke, Jana, Schön, Marian, Simeth, Jakob, Köstler, Josef, Siegmund, Heiko, Ugele, Ines, Paulus, Michael, Dietl, Alexander, Kolodova, Kristina, Steines, Louisa, Freitag, Katharina, Peuker, Alice, Schönhammer, Gabriele, Raithel, Johanna, Graf, Bernhard, Geismann, Florian, Lubnow, Matthias, Mack, Matthias, Hau, Peter, Bohr, Christopher, Burkhardt, Ralph, Gessner, Andre, Salzberger, Bernd, Wagner, Ralf, Hanses, Frank, Hitzenbichler, Florian, Heudobler, Daniel, Lüke, Florian, Pukrop, Tobias, Herr, Wolfgang, Wolff, Daniel, Spang, Rainer, Poeck, Hendrik, Hoffmann, Petra, Jantsch, Jonathan, Brochhausen, Christoph, Lunz, Dirk, Rehli, Michael, Kreutz, Marina, Renner, Kathrin

“…Metabolic pathways regulate immune responses and disrupted metabolism leads to immune dysfunction and disease. Coronavirus disease 2019 (COVID-19) is driven by…”
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Abstract 16339: Mitochondrial Function in Animal and Novel Human Disease Models of Tachycardiomyopathy by Paulus, Michael G, Renner, Kathrin, Pabel, Steffen, Pietrzyk, Gabriela, Luchner, Andreas, Maier, Lars S, Birner, Christoph M, Streckfuß-Bömeke, Katrin, Sossalla, Samuel T, Dietl, Alexander

“…IntroductionClinical significance of tachycardiomyopathy (TCM) increased with trials on catheter ablation therapy. Myocardial biopsies from patients show…”
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Alterations of the renin angiotensin system in human end-stage heart failure before and after mechanical cardiac unloading by LVAD support by Messmann, Rebecca, Dietl, Alexander, Wagner, Stefan, Domenig, Oliver, Jungbauer, Carsten, Luchner, Andreas, Maier, Lars S., Schopka, Simon, Hirt, Stephan, Schmid, Christof, Birner, Christoph

“…Heart transplantation is often an unrealizable therapeutic option for end-stage heart failure, which is why mechanical left ventricular assist devices (LVADs)…”
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Increasing social welfare by taxing pesticide externalities in the Indian cotton sector by Rasche, Livia, Dietl, Alexander, Shakhramanyan, Nikolinka, Pandey, Divya, Schneider, Uwe A

“…BACKGROUND Pesticide use in the Indian cotton industry has decreased with the introduction of Bt cotton, but rates are still high in comparison with other…”
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Tachycardiomyopathy entails a dysfunctional pattern of interrelated mitochondrial functions by Paulus, Michael G., Renner, Kathrin, Nickel, Alexander G., Brochhausen, Christoph, Limm, Katharina, Zügner, Elmar, Baier, Maria J., Pabel, Steffen, Wallner, Stefan, Birner, Christoph, Luchner, Andreas, Magnes, Christoph, Oefner, Peter J., Stark, Klaus J., Wagner, Stefan, Maack, Christoph, Maier, Lars S., Streckfuss-Bömeke, Katrin, Sossalla, Samuel, Dietl, Alexander

“…Tachycardiomyopathy is characterised by reversible left ventricular dysfunction, provoked by rapid ventricular rate. While the knowledge of mitochondria…”
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Interatrial differences of basal molecular set-up and changes in tachycardia-induced heart failure-a proteomic profiling study by Dietl, Alexander, Winkel, Ingrid, Deutzmann, Rainer, Schröder, Josef, Hupf, Julian, Riegger, Günter, Luchner, Andreas, Birner, Christoph

“…Aims Left and right atria show compelling differences regarding organogenesis and specific clinical diseases. In congestive heart failure (CHF), remodelling of…”
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Long-term outcomes and predictors of recurrence after pulmonary vein isolation with multielectrode ablation catheter in patients with atrial fibrillation by Fredersdorf, Sabine, Fenzl, Carolin, Jungbauer, Carsten, Weber, Stefan, von Bary, Christian, Dietl, Alexander, Seegers, Joachim, Maier, Lars S, Ücer, Ekrem

“…PURPOSEDespite various techniques used in atrial fibrillation ablation, recurrence of atrial arrhythmias still constitutes a clinical problem. The aim of this…”
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Treatments targeting inotropy - A position paper of the Committees on Translational Research and Acute Heart Failure of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) by Maack, Christoph, Eschenhagen, Thomas, Hamdani, Nazha, Heinzel, Frank R, Lyon, Alexander, Manstein, Dietmar, Metzger, Joseph, Papp, Zoltán, Tocchetti, Carlo G, Birhan Yilmaz, M, Anker, Stefan D, Balligand, Jean-Luc, Bauersachs, Johann, Brutsaert, Dirk, Carrier, Lucie, Chlopicki, Stefan, Cleland, John G, de Boer, Rudolf A, Dietl, Alexander, Fischmeister, Rodolphe, Harjola, Veli-Pekka, Heymans, Stephane, Hilfiker-Kleiner, Denise, Holzmeister, Johannes, de Keulenaer, Gilles, Limongelli, Giuseppe, Linke, Wolfgang A, Lund, Lars H, Masip, Josep, Metra, Marco, Mueller, Christian, Pieske, Burkert, Ponikowski, Piotr, Ristić, Arsen, Ruschitzka, Frank, Seferović, Petar M, Skouri, Hadi, Zimmermann, Wolfram H., Mebazaa, Alexandre

“…Acute heart failure (HF) and in particular, cardiogenic shock are associated with high morbidity and mortality. A therapeutic dilemma is that the use of…”
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Cardiovascular Risk Factor Control in 70- to 95-Year-Old Individuals: Cross-Sectional Results from the Population-Based AugUR Study by Donhauser, Ferdinand J, Zimmermann, Martina E, Steinkirchner, Anna B, Wiegrebe, Simon, Dietl, Alexander, Brandl, Caroline, Burkhardt, Ralph, Gessner, André, Schweda, Frank, Bergler, Tobias, Schäffner, Elke, Böger, Carsten A, Kronenberg, Florian, Luchner, Andreas, Stark, Klaus J, Heid, Iris M

“…Cardiovascular risk factors such as high glucose, LDL-cholesterol, blood pressure, and impaired kidney function are particularly frequent in old-aged…”
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