Search Results - "Dieterich, C."
-
1
Mechanisms of extracellular vesicle-mediated immune evasion in melanoma
Published in Frontiers in immunology (23-08-2022)“…Melanoma-derived extracellular vesicles (EVs) have been found to promote tumor growth and progression, and to predict patient responsiveness to immunotherapy…”
Get full text
Journal Article -
2
Metabolic turnover of synaptic proteins: kinetics, interdependencies and implications for synaptic maintenance
Published in PloS one (02-05-2013)“…Chemical synapses contain multitudes of proteins, which in common with all proteins, have finite lifetimes and therefore need to be continuously replaced…”
Get full text
Journal Article -
3
Proteomics of the Synapse – A Quantitative Approach to Neuronal Plasticity
Published in Molecular & cellular proteomics (01-02-2016)“…The advances in mass spectrometry based proteomics in the past 15 years have contributed to a deeper appreciation of protein networks and the composition of…”
Get full text
Journal Article -
4
Cell-type-specific metabolic labeling of nascent proteomes in vivo
Published in Nature biotechnology (01-12-2017)“…Proteomes of distinct cell types in the brains of live mice are labeled and quantitated with a genetically encoded non-canonical amino-acid labeling method and…”
Get full text
Journal Article -
5
Summer hydrographic changes in the Baltic Sea, Kattegat and Skagerrak projected in an ensemble of climate scenarios downscaled with a coupled regional ocean–sea ice–atmosphere model
Published in Climate dynamics (01-11-2019)“…This model study investigates summer hydrographic changes in response to climate projections following the CMIP5 RCP8.5 scenario. We use the high resolution…”
Get full text
Journal Article -
6
Modeling the combined impact of changing climate and changing nutrient loads on the Baltic Sea environment in an ensemble of transient simulations for 1961–2099
Published in Climate dynamics (01-11-2012)“…The combined future impacts of climate change and industrial and agricultural practices in the Baltic Sea catchment on the Baltic Sea ecosystem were assessed…”
Get full text
Journal Article -
7
Mechanisms and Clinical Significance of Tumor Lymphatic Invasion
Published in Cells (Basel, Switzerland) (29-09-2021)“…Tumor-associated lymphatic vessels play an important role in tumor progression, mediating lymphatic dissemination of malignant cells to tumor-draining lymph…”
Get full text
Journal Article -
8
In situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons
Published in Nature neuroscience (01-07-2010)“…Dieterich et al . describe a methodology to label all newly synthesized neuronal proteins in situ . This method, which they name FUNCAT, relies on the…”
Get full text
Journal Article -
9
Is interactive air sea coupling relevant for simulating the future climate of Europe?
Published in Climate dynamics (2021)“…The majority of regional climate change assessments for the Euro-CORDEX region is based on high resolution atmosphere models. These models use prescribed lower…”
Get full text
Journal Article -
10
An important role of podoplanin in hair follicle growth
Published in PloS one (23-07-2019)“…Podoplanin (PDPN) is a glycoprotein that is expressed by various cell types, including keratinocytes, fibroblasts, and lymphatic endothelial cells. We found…”
Get full text
Journal Article -
11
Microfluidic Local Perfusion Chambers for the Visualization and Manipulation of Synapses
Published in Neuron (Cambridge, Mass.) (15-04-2010)“…The polarized nature of neurons and the size and density of synapses complicates the manipulation and visualization of cell biological processes that control…”
Get full text
Journal Article -
12
Lymphatic vessels: new targets for the treatment of inflammatory diseases
Published in Angiogenesis (London) (01-04-2014)“…The lymphatic system plays an important role in the physiological control of the tissue fluid balance and in the initiation of immune responses. Recent studies…”
Get full text
Journal Article -
13
Cell-selective proteomics segregates pancreatic cancer subtypes by extracellular proteins in tumors and circulation
Published in Nature communications (08-05-2023)“…Cell-selective proteomics is a powerful emerging concept to study heterocellular processes in tissues. However, its high potential to identify…”
Get full text
Journal Article -
14
Identification of circular RNAs with host gene-independent expression in human model systems for cardiac differentiation and disease
Published in Journal of molecular and cellular cardiology (01-08-2017)“…Cardiovascular disease, one of the most common causes of death in western populations, is characterized by changes in RNA splicing and expression. Circular…”
Get full text
Journal Article -
15
Melanoma‐derived extracellular vesicles mediate lymphatic remodelling and impair tumour immunity in draining lymph nodes
Published in Journal of extracellular vesicles (01-02-2022)“…Tumour‐draining lymph nodes (LNs) undergo massive remodelling including expansion of the lymphatic sinuses, a process that has been linked to lymphatic…”
Get full text
Journal Article -
16
An Important Role of VEGF-C in Promoting Lymphedema Development
Published in Journal of investigative dermatology (01-09-2017)“…Secondary lymphedema is a common complication after cancer treatment, but the pathomechanisms underlying the disease remain unclear. Using a mouse tail…”
Get full text
Journal Article -
17
Selective Identification of Newly Synthesized Proteins in Mammalian Cells Using Bioorthogonal Noncanonical Amino Acid Tagging (BONCAT)
Published in Proceedings of the National Academy of Sciences - PNAS (20-06-2006)“…In both normal and pathological states, cells respond rapidly to environmental cues by synthesizing new proteins. The selective identification of a newly…”
Get full text
Journal Article -
18
Mechanisms of Tumor-Induced Lymphovascular Niche Formation in Draining Lymph Nodes
Published in Cell reports (Cambridge) (26-12-2018)“…Enlargement of the lymphatic vascular network in tumor-draining lymph nodes (LNs) often precedes LN metastasis, likely providing a lymphovascular niche for…”
Get full text
Journal Article -
19
Manipulation of DHPS activity affects dendritic morphology and expression of synaptic proteins in primary rat cortical neurons
Published in Frontiers in cellular neuroscience (14-10-2024)“…Deoxyhypusine synthase (DHPS) catalyzes the initial step of hypusine incorporation into the eukaryotic initiation factor 5A (eIF5A), leading to its activation…”
Get full text
Journal Article -
20
Lymphatic MAFB regulates vascular patterning during developmental and pathological lymphangiogenesis
Published in Angiogenesis (London) (01-08-2020)“…MAFB is a transcription factor involved in the terminal differentiation of several cell types, including macrophages and keratinocytes. MAFB is also expressed…”
Get full text
Journal Article