Search Results - "Dieter Blaas"
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Viral entry pathways: the example of common cold viruses
Published in Wiener medizinische Wochenschrift (01-05-2016)“…Summary For infection, viruses deliver their genomes into the host cell. These nucleic acids are usually tightly packed within the viral capsid, which, in…”
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Rhinovirus Inhibitors: Including a New Target, the Viral RNA
Published in Viruses (07-09-2021)“…Rhinoviruses (RVs) are the main cause of recurrent infections with rather mild symptoms characteristic of the common cold. Nevertheless, RVs give rise to…”
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3
A novel mechanism of antibody-mediated enhancement of flavivirus infection
Published in PLoS pathogens (01-09-2017)“…Antibody-dependent enhancement of viral infection is a well-described phenomenon that is based on the cellular uptake of infectious virus-antibody complexes…”
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4
Uncoating of human rhinoviruses
Published in Reviews in medical virology (01-09-2010)“…Human rhinoviruses (HRVs) are a major cause of the common cold. The more than one hundred serotypes, divided into species HRV‐A and HRV‐B, either bind…”
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Human Rhinovirus Subviral A Particle Binds to Lipid Membranes over a Twofold Axis of Icosahedral Symmetry
Published in Journal of Virology (01-10-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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nanoDSF: In vitro Label-Free Method to Monitor Picornavirus Uncoating and Test Compounds Affecting Particle Stability
Published in Frontiers in microbiology (26-06-2020)“…Thermal shift assays measure the stability of macromolecules and macromolecular assemblies as a function of temperature. The Particle Stability Thermal Release…”
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Aichivirus A1 replicates in human intestinal epithelium and bronchial tissue: Lung–gut axis?
Published in Virus research (01-04-2024)“…•AiV-A1 replicates in ApoA1 and Ki-67 positive cells of stem cell-derived human small intestinal epithelium model.•AiV-A1 infection of intestinal cells…”
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Cellular N-myristoyltransferases play a crucial picornavirus genus-specific role in viral assembly, virion maturation, and infectivity
Published in PLoS pathogens (01-08-2018)“…In nearly all picornaviruses the precursor of the smallest capsid protein VP4 undergoes co-translational N-terminal myristoylation by host cell…”
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Multiple receptors involved in human rhinovirus attachment to live cells
Published in Proceedings of the National Academy of Sciences - PNAS (18-11-2008)“…Minor group human rhinoviruses (HRVs) attach to members of the low-density lipoprotein receptor family and are internalized via receptor-mediated endocytosis…”
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10
Sensing Picornaviruses Using Molecular Imprinting Techniques on a Quartz Crystal Microbalance
Published in Analytical chemistry (Washington) (01-07-2009)“…Molecular imprinting techniques were adapted to design a sensor for the human rhinovirus (HRV) and the foot-and-mouth disease virus (FMDV), which are two…”
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Recent developments in capillary and chip electrophoresis of bioparticles: Viruses, organelles, and cells
Published in Electrophoresis (01-06-2011)“…In appropriate aqueous buffer solutions, biological particles usually exhibit a particular electric surface charge due to exposed charged or chargeable…”
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Insights into minor group rhinovirus uncoating: the X-ray structure of the HRV2 empty capsid
Published in PLoS pathogens (01-01-2012)“…Upon attachment to their respective receptor, human rhinoviruses (HRVs) are internalized into the host cell via different pathways but undergo similar…”
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Uncoating of common cold virus is preceded by RNA switching as determined by X-ray and cryo-EM analyses of the subviral A-particle
Published in Proceedings of the National Academy of Sciences - PNAS (10-12-2013)“…During infection, viruses undergo conformational changes that lead to delivery of their genome into host cytosol. In human rhinovirus A2, this conversion is…”
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Stabilization of the Quadruplex-Forming G-Rich Sequences in the Rhinovirus Genome Inhibits Uncoating-Role of Na + and K
Published in Viruses (01-04-2023)“…Rhinoviruses (RVs) are the major cause of common cold, a respiratory disease that generally takes a mild course. However, occasionally, RV infection can lead…”
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Viral uncoating is directional: exit of the genomic RNA in a common cold virus starts with the poly-(A) tail at the 3'-end
Published in PLoS pathogens (01-04-2013)“…Upon infection, many RNA viruses reorganize their capsid for release of the genome into the host cell cytosol for replication. Often, this process is triggered…”
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A New, Simple Method for Linking of Antibodies to Atomic Force Microscopy Tips
Published in Bioconjugate chemistry (01-07-2007)“…Functionalization of atomic force microscope (AFM) tips with bioligands converts them into monomolecular biosensors which can detect complementary receptor…”
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Monolithic anion-exchange chromatography yields rhinovirus of high purity
Published in Journal of virological methods (01-01-2018)“…[Display omitted] •Human Rhinovirus (RV) purification and polishing is investigated.•Monolithic ion-exchange chromatography is employed in this context.•RV…”
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Capillary electrophoresis of biological particles: Viruses, bacteria, and eukaryotic cells
Published in Electrophoresis (01-07-2004)“…A review about the application of electrophoretic methods in the capillary format for the investigation of large biological assemblies like viruses, bacteria,…”
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Productive Entry Pathways of Human Rhinoviruses
Published in Advances in virology (01-01-2012)“…Currently, complete or partial genome sequences of more than 150 human rhinovirus (HRV) isolates are known. Twelve species A use members of the low-density…”
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Catching Common Cold Virus with a Net: Pyridostatin Forms Filaments in Tris Buffer That Trap Viruses-A Novel Antiviral Strategy?
Published in Viruses (04-07-2020)“…The neutrophil extracellular trap (ET) is a eukaryotic host defense machinery that operates by capturing and concentrating pathogens in a filamentous network…”
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