Search Results - "Dierickx, P J"
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In vitro long-term cytotoxicity testing of 27 MEIC chemicals on Hep G2 cells and comparison with acute human toxicity data
Published in Toxicology in vitro (01-04-2001)“…Within the framework of the EDIT (Evaluation guided Development of In vitro Toxicity and toxicokinetic tests) programme, the long-term cytotoxicity of 27…”
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Formation of reactive oxygen species in rat hepatoma-derived Fa32 cells to predict human toxicity
Published in Toxicology in vitro (01-12-2002)“…The cytotoxicity of the MEIC (Multicentre Evaluation of In vitro Cytotoxicity) reference chemicals was investigated by measuring the increased reactive oxygen…”
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CYP1/2 Activation and Glutathione-dependent Cytotoxicity of Four Pesticides in Hep G2 and Fa32 Cells
Published in Toxicology in vitro (01-08-1999)“…The cytotoxicity of the carbamate insecticide carbaryl, the organophosphate insecticide quinalphos, the benzimidazole fungicide benomyl, and its…”
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Glutathione-dependent cytotoxicity of the chloroacetanilide herbicides alachlor, metolachlor, and propachlor in rat and human hepatoma-derived cultured cells
Published in Cell biology and toxicology (1999)“…Alachlor, metolachlor, and propachlor are widely used chloroacetanilide herbicides. Their cytotoxicity in rat (Fa32) and human (Hep G2) hepatoma-derived cells…”
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Glutathione S-transferases of Aulacorthum solani and Acyrthosiphon pisum: partial purification and characterization
Published in Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology (01-05-2001)“…Glutathione S-transferases (GST) play an important role in the detoxification of many substances including allelochemicals from plants. Brassicaceae plants…”
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The role of oxidative stress on the effect of 1,4,7,10,13,16-hexathiacyclooctadecane on copper and zinc toxicity in HepG2 cells
Published in Human & experimental toxicology (01-02-2003)“…Experiments have shown that 1,4,7,10,13,16-hexathiacyclooctadecane (L3) increased the Cu2+ toxicity on HepG2 cells, whereas the combination Zn(2+)/L3 was less…”
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Increased cytotoxic sensitivity of cultured FHM fish cells by simultaneous treatment with sodium dodecyl sulfate and buthionine sulfoximine
Published in Chemosphere (Oxford) (01-03-1998)“…A previously described neutral red uptake inhibition assay on cultured fathead minnow (FHM) fish cells revealed a good correlation with fish toxicity data…”
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In vitro cytotoxicity testing for prediction of acute human toxicity
Published in Cell biology and toxicology (01-06-1994)“…This study was designed to compare the cytotoxic concentrations of chemicals, determined with three independent in vitro cytotoxicity testing protocols, with…”
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Comparative cytotoxicity of 5-aminosalicylic acid (mesalazine) and related compounds in different cell lines
Published in Cell biology and toxicology (01-10-1997)“…Nonsteroidal anti-inflammatory drugs can cause serious side-effects such as tubulo-interstitial nephritis. Mesalazine (5-ASA, 5-aminosalicylic acid) is used…”
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Toxicological Evaluation of Waste-Water Samples to Appropriately Sensitized Cultured Fathead Minnow Cells Compared with the Microtox Assay
Published in Bulletin of environmental contamination and toxicology (01-02-2002)“…We have previously shown that a good correlation exists between in vitro cytotoxicity data to cultured fathead minnow (FHM) fish cells and fish lethality data…”
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The effect of hexaaza- and hexathia-macrocyclic ligands on transition metal cytotoxicity in human hepatoma-derived cultured cells
Published in Human & experimental toxicology (01-08-2002)“…The effect of macrocyclic ligands on cytotoxic concentrations of the transition metal ions of copper, zinc, and cadmium was investigated. For this purpose, a…”
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Cytotoxicity of mercury compounds in LLC-PK1, MDCK and human proximal tubular cells
Published in Kidney international (01-02-1995)“…Cytotoxicity of mercury compounds in LLC-PK1, MDCK and human proximal tubular cells. Six mercury compounds [HgCl2 (MC), Hg(CH3COO)2 (MA), Hg(NO3)2 (MN),…”
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Journal Article Conference Proceeding -
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Glutathione protection against hydrogen peroxide, tert-butyl hydroperoxide and diamide cytotoxicity in rat hepatoma-derived Fa32 cells
Published in Human & experimental toxicology (01-10-1999)“…1. Several ozonides, peroxides and aldehydes are formed during ozone therapy, recently introduced in medicine. tert-Butyl hydroperoxide (t-BHP), H2O2 and…”
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Cytotoxicity of the MEIC reference chemicals in antioxidant-enriched, rat hepatoma-derived Fa32 cells
Published in Alternatives to laboratory animals (01-05-2001)“…Since vitamin E increases the antioxidant status of cells, its influence on cytotoxicity was investigated. The neutral red uptake (NRU) inhibition effects of…”
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Correlation between the in vitro cytotoxicity of inorganic metal compounds to cultured fathead minnow fish cells and the toxicity to Daphnia magna
Published in Bulletin of environmental contamination and toxicology (01-07-1996)“…The cytotoxicity of inorganic salts of 19 metals to cultured fathead minnow(FHM) cells was measured by the neutral red uptake inhibition assay and compared…”
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Effect of diet and beta-naphthoflavone on hepatic and renal glutathione S-transferase isoenzymes in carp (Cyprinus carpio)
Published in Fish physiology and biochemistry (01-03-1998)“…Glutathione S-transferase (GST) isoenzymes were isolated from liver and kidney of carp (Cyprinus carpio) by glutathione affinity chromatography and…”
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Interaction of 1,4-benzoquinone and 2,4-dichlorophenoxyacetic acid with microsomal glutathione transferase from rat liver
Published in Archives internationales de physiologie et de biochimie (1988)“…Glutathione transferase (GST) was purified from the microsomes of rat liver by glutathione affinity chromatography. The interaction of…”
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Cytotoxicity of the MEIC reference chemicals in rat hepatoma-derived Fa32 cells
Published in Toxicology (Amsterdam) (07-09-2000)“…The cytotoxicity of the MEIC reference chemicals was investigated in rat hepatoma-derived Fa32 cells. The total protein content was measured as an endpoint…”
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Correlation of the neutral red uptake inhibition assay of cultured fathead minnow fish cells with fish lethality tests
Published in Bulletin of environmental contamination and toxicology (01-05-1991)“…Fathead minnow cells were incubated for 2 h with one of 29 chemicals belonging to the groups of inorganic compounds, alcohols, acid, ketones, and others then…”
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