Search Results - "Dierck, Kevin"

SHIP1 Is Present but Strongly Downregulated in T-ALL, and after Restoration Suppresses Leukemia Growth in a T-ALL Xenotransplantation Mouse Model by Ehm, Patrick, Rietow, Ruth, Wegner, Wiebke, Bußmann, Lara, Kriegs, Malte, Dierck, Kevin, Horn, Stefan, Streichert, Thomas, Horstmann, Martin, Jücker, Manfred

“…Acute lymphoblastic leukemia (ALL) is the most common cause of cancer-related death in children. Despite significantly increased chances of cure, especially…”
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High-Throughput Phosphotyrosine Profiling Using SH2 Domains by Machida, Kazuya, Thompson, Christopher M., Dierck, Kevin, Jablonowski, Karl, Kärkkäinen, Satu, Liu, Bernard, Zhang, Haimin, Nash, Piers D., Newman, Debra K., Nollau, Peter, Pawson, Tony, Renkema, G. Herma, Saksela, Kalle, Schiller, Martin R., Shin, Dong-Guk, Mayer, Bruce J.

“…Protein tyrosine phosphorylation controls many aspects of signaling in multicellular organisms. One of the major consequences of tyrosine phosphorylation is…”
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Aberrant ZNF423 impedes B cell differentiation and is linked to adverse outcome of ETV6-RUNX1 negative B precursor acute lymphoblastic leukemia by Harder, Lena, Eschenburg, Georg, Zech, Antonia, Kriebitzsch, Neele, Otto, Benjamin, Streichert, Thomas, Behlich, Anna-Sophie, Dierck, Kevin, Klingler, Bine, Hansen, Arne, Stanulla, Martin, Zimmermann, Martin, Kremmer, Elisabeth, Stocking, Carol, Horstmann, Martin A

“…Differentiation arrest is a hallmark of acute leukemia. Genomic alterations in B cell differentiation factors such as PAX5, IKZF1, and EBF-1 have been…”
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PML domain of PML–RARα blocks senescence to promote leukemia by Korf, Katharina, Wodrich, Harald, Haschke, Alexander, Ocampo, Corinne, Harder, Lena, Gieseke, Friederike, Pollmann, Annika, Dierck, Kevin, Prall, Sebastian, Staege, Hannah, Ma, Hui, Horstmann, Martin A., Evans, Ronald M., Sternsdorf, Thomas

“…In most acute promyelocytic leukemia (APL) cases, translocons produce a promyelocytic leukemia protein–retinoic acid receptor α (PML–RARα) fusion gene…”
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Technical Note From Industry: A New Compression Garment, JOBST Relax, BSN Medical, Inc by Bell, Lesli, Dierck, Kevin

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Key Nodes In FLT3 Dependent Signaling Determine Growth and Survival Of Childhood Acute Lymphoblastic Leukemia by Dierck, Kevin, Siekmann, Ina, Prall, Sebastian, Beck, Florian, Jeremias, Irmela, Sickmann, Albert, Horstmann, Martin A.

“…The balanced regulation of complex signaling networks plays an important role in cell proliferation, survival and apoptosis. Receptor tyrosine kinase (RTK)…”
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Abstract 2950: Regulation of the functional interface between nucleotide excision repair and transcription by MITF modulates melanoma growth by Seoane, Marcos, Raluy, Laia Pagerols, Kaufmann, Karoline, Strauss, Julia, Dierck, Kevin, Thomale, Jüergen, Brandner, Johanna M., Schumacher, Udo, Nollau, Peter, Wild, Peter J., Zimmermann, Martin, Du, Jinyan, Fisher, David E., Horstmann, Martin A.

“…Abstract Nucleotide excision repair (NER) is an essential instrument to maintain genomic stability in eukaryotes especially towards ultraviolet radiation…”
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The PML domain of PML-RAR[Alpha] blocks senescence to promote leukemia by Korf, Katharina, Wodrich, Harald, Haschke, Alexander, Ocampo, Corinne, Harder, Lena, Gieseke, Friederike, Pollmann, Annika, Dierck, Kevin, Prall, Sebastian, Staege, Hannah, Ma, Hui, Horstmann, Martin A, Evans, Ronald M, Sternsdorf, Thomas

“…In most acute promyelocytic leukemia (APL) cases, translocons produce a promyelocytic leukemia protein- retinoic acid receptor α (PML-RARα) fusion gene…”
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Combined inhibition of receptor tyrosine and p21-activated kinases as a therapeutic strategy in childhood ALL by Siekmann, Ina-Katrin, Dierck, Kevin, Prall, Sebastian, Klokow, Marianne, Strauss, Julia, Buhs, Sophia, Wrzeszcz, Antonina, Bockmayr, Michael, Beck, Florian, Trochimiuk, Magdalena, Gottschling, Kristina, Martens, Victoria, Khosh-Naucke, Melissa, Gerull, Helwe, Müller, Jürgen, Behrmann, Lena, Blohm, Martin, Zahedi, René P., Jeremias, Irmela, Sickmann, Albert, Nollau, Peter, Horstmann, Martin A.

“…Receptor tyrosine kinase (RTK)-dependent signaling has been implicated in the pathogenesis of acute lymphoblastic leukemia (ALL) of childhood. However, the…”
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Profiling the tyrosine phosphorylation state using SH2 domains by Dierck, Kevin, Machida, Kazuya, Mayer, Bruce J, Nollau, Peter

“…Global monitoring of cellular signaling activity is of great importance for the understanding of the regulation of complex signaling networks and the…”
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Quantitative multiplexed profiling of cellular signaling networks using phosphotyrosine-specific DNA-tagged SH2 domains by Nollau, Peter, Dierck, Kevin, Machida, Kazuya, Voigt, Anja, Thimm, Julian, Horstmann, Martin, Fiedler, Walter, Mayer, Bruce J

“…Deciphering global signaling networks is of great importance for the detailed understanding of cellular signaling processes controlling many important…”
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