Search Results - "Dienes, Hans"

Age and Sex but Not ATP7B Genotype Effectively Influence the Clinical Phenotype of Wilson Disease by Ferenci, Peter, Stremmel, Wolfgang, Członkowska, Anna, Szalay, Ferenc, Viveiros, André, Stättermayer, Albert Friedrich, Bruha, Radan, Houwen, Roderick, Pop, Tudor Lucian, Stauber, Rudolf, Gschwantler, Michael, Pfeiffenberger, Jan, Yurdaydin, Cihan, Aigner, Elmar, Steindl‐Munda, Petra, Dienes, Hans‐Peter, Zoller, Heinz, Weiss, Karl Heinz

“…Wilson disease (WD) is an inherited disorder of hepatic copper metabolism with considerable variation in clinical presentations, the most common ones being…”
Get full text

MicroRNA gene expression profile of hepatitis C virus–associated hepatocellular carcinoma by Varnholt, Heike, Drebber, Uta, Schulze, Falko, Wedemeyer, Inga, Schirmacher, Peter, Dienes, Hans‐Peter, Odenthal, Margarete

“…MicroRNAs are small noncoding RNAs that regulate gene expression by targeting messenger RNAs (mRNAs) through translational repression or RNA degradation. Many…”
Get full text

Simplified criteria for the diagnosis of autoimmune hepatitis by Hennes, Elke M., Zeniya, Mikio, Czaja, Albert. J., Parés, Albert, Dalekos, George N., Krawitt, Edward L., Bittencourt, Paulo L., Porta, Gilda, Boberg, Kirsten M., Hofer, Harald, Bianchi, Francesco B., Shibata, Minoru, Schramm, Christoph, Eisenmann de Torres, Barbara, Galle, Peter R., McFarlane, Ian, Dienes, Hans‐Peter, Lohse, Ansgar W.

“…Diagnosis of autoimmune hepatitis (AIH) may be challenging. However, early diagnosis is important because immunosuppression is life‐saving. Diagnostic criteria…”
Get full text

Severe acute liver disease in adults: Contemporary role of histopathology by Clouston, Andrew D, Gouw, Annette S H, Tiniakos, Dina, Bedossa, Pierre, Brunt, Elizabeth M, Callea, Francesco, Dienes, Hans‐Peter, Goodman, Zachary D, Hubscher, Stefan G, Kakar, Sanjay, Kleiner, David E, Lackner, Carolin, Park, Young N, Roberts, Eve A, Schirmacher, Peter, Terracciano, Luigi, Torbenson, Michael, Wanless, Ian R, Zen, Yoh, Burt, Alastair D

“…Liver biopsies have consistently contributed to our understanding of the pathogenesis and aetiologies of acute liver disease. As other diagnostic modalities…”
Get full text

Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation by Bakiri, Latifa, Hamacher, Rainer, Graña, Osvaldo, Guío-Carrión, Ana, Campos-Olivas, Ramón, Martinez, Lola, Dienes, Hans P, Thomsen, Martin K, Hasenfuss, Sebastian C, Wagner, Erwin F

“…Human hepatocellular carcinomas (HCCs), which arise on a background of chronic liver damage and inflammation, express c-Fos, a component of the AP-1…”
Get full text

Hepatic and serum levels of miR-122 after chronic HCV-induced fibrosis by Trebicka, Jonel, Anadol, Evrim, Elfimova, Natalia, Strack, Ingo, Roggendorf, Michael, Viazov, Sergei, Wedemeyer, Inga, Drebber, Uta, Rockstroh, Jürgen, Sauerbruch, Tilman, Dienes, Hans-Peter, Odenthal, Margarete

“…Background & Aims The progression of liver fibrosis in patients with chronic hepatitis C (CHC) is important to decide on the treatment of the virus. As liver…”
Get full text

Consensus recommendations for histological criteria of autoimmune hepatitis from the International AIH Pathology Group: Results of a workshop on AIH histology hosted by the European Reference Network on Hepatological Diseases and the European Society of Pathology by Lohse, Ansgar W., Sebode, Marcial, Bhathal, Prithi S., Clouston, Andrew D., Dienes, Hans P., Jain, Dhanpat, Gouw, Annette S. H., Guindi, Maha, Kakar, Sanjay, Kleiner, David E., Krech, Till, Lackner, Carolin, Longerich, Thomas, Saxena, Romil, Terracciano, Luigi, Washington, Kay, Weidemann, Sören, Hübscher, Stefan G., Tiniakos, Dina

“…Abstract Background & Aims Diagnostic histological criteria for autoimmune hepatitis (AIH) have not been clearly established. Previously published criteria…”
Get full text

New Lineage of Lassa Virus, Togo, 2016 by Whitmer, Shannon L M, Strecker, Thomas, Cadar, Daniel, Dienes, Hans-Peter, Faber, Kelly, Patel, Ketan, Brown, Shelley M, Davis, William G, Klena, John D, Rollin, Pierre E, Schmidt-Chanasit, Jonas, Fichet-Calvet, Elisabeth, Noack, Bernd, Emmerich, Petra, Rieger, Toni, Wolff, Svenja, Fehling, Sarah Katharina, Eickmann, Markus, Mengel, Jan Philipp, Schultze, Tilman, Hain, Torsten, Ampofo, William, Bonney, Kofi, Aryeequaye, Juliana Naa Dedei, Ribner, Bruce, Varkey, Jay B, Mehta, Aneesh K, Lyon, 3rd, G Marshall, Kann, Gerrit, De Leuw, Philipp, Schuettfort, Gundolf, Stephan, Christoph, Wieland, Ulrike, Fries, Jochen W U, Kochanek, Matthias, Kraft, Colleen S, Wolf, Timo, Nichol, Stuart T, Becker, Stephan, Ströher, Ute, Günther, Stephan

“…We describe a strain of Lassa virus representing a putative new lineage that was isolated from a cluster of human infections with an epidemiologic link to…”
Get full text

Intrahepatic myeloid-cell aggregates enable local proliferation of CD8+ T cells and successful immunotherapy against chronic viral liver infection by Huang, Li-Rung, Wohlleber, Dirk, Reisinger, Florian, Jenne, Craig N, Cheng, Ru-Lin, Abdullah, Zeinab, Schildberg, Frank A, Odenthal, Margarete, Dienes, Hans-Peter, van Rooijen, Nico, Schmitt, Edgar, Garbi, Natalio, Croft, Michael, Kurts, Christian, Kubes, Paul, Protzer, Ulrike, Heikenwalder, Mathias, Knolle, Percy A

“…Chronic infections are commonly established in the liver. Knolle and colleagues show that cytotoxic T lymphocyte responses can be boosted by TLR-mediated…”
Get full text

Hepatitis C virus infection triggers a tumor‐like glutamine metabolism by Lévy, Pierre L., Duponchel, Sarah, Eischeid, Hannah, Molle, Jennifer, Michelet, Maud, Diserens, Gaëlle, Vermathen, Martina, Vermathen, Peter, Dufour, Jean‐Francois, Dienes, Hans‐Peter, Steffen, Hans‐Michael, Odenthal, Margarete, Zoulim, Fabien, Bartosch, Birke

“…Chronic infection with hepatitis C virus (HCV) is one of the main causes of hepatocellular carcinoma. However, the molecular mechanisms linking the infection…”
Get full text

Hepatic steatosis in Wilson disease – Role of copper and PNPLA3 mutations by Stättermayer, Albert Friedrich, Traussnigg, Stefan, Dienes, Hans-Peter, Aigner, Elmar, Stauber, Rudolf, Lackner, Karoline, Hofer, Harald, Stift, Judith, Wrba, Friedrich, Stadlmayr, Andreas, Datz, Christian, Strasser, Michael, Maieron, Andreas, Trauner, Michael, Ferenci, Peter

“…Background & Aims The earliest characteristic alterations of the liver pathology in Wilson disease (WD) include steatosis, which is sometimes indistinguishable…”
Get full text

EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients by Srivatsa, Sriram, Paul, Mariel C, Cardone, Claudia, Holcmann, Martin, Amberg, Nicole, Pathria, Paulina, Diamanti, Michaela A, Linder, Markus, Timelthaler, Gerald, Dienes, Hans P, Kenner, Lukas, Wrba, Fritz, Prager, Gerald W, Rose-John, Stefan, Eferl, Robert, Liguori, Giuseppina, Botti, Gerardo, Martinelli, Erika, Greten, Florian R, Ciardiello, Fortunato, Sibilia, Maria

“…Background & Aims Inhibitors of the epidermal growth factor receptor (EGFR) are the first-line therapy for patients with metastatic colorectal tumors without…”
Get full text

Atorvastatin attenuates hepatic fibrosis in rats after bile duct ligation via decreased turnover of hepatic stellate cells by Trebicka, Jonel, Hennenberg, Martin, Odenthal, Margarete, Shir, Khanwali, Klein, Sabine, Granzow, Michaela, Vogt, Annabelle, Dienes, Hans-Peter, Lammert, Frank, Reichen, Jürg, Heller, Jörg, Sauerbruch, Tilman

“…Background & Aims Activation of hepatic stellate cells (HSC) and transdifferentiation to myofibroblasts following liver injury is the main culprit for hepatic…”
Get full text

Hepatocyte growth factor (HGF) inhibits collagen I and IV synthesis in hepatic stellate cells by miRNA-29 induction by Kwiecinski, Monika, Noetel, Andrea, Elfimova, Natalia, Trebicka, Jonel, Schievenbusch, Stephanie, Strack, Ingo, Molnar, Levente, von Brandenstein, Melanie, Töx, Ulrich, Nischt, Roswitha, Coutelle, Oliver, Dienes, Hans Peter, Odenthal, Margarete

“…In chronic liver disease, hepatic stellate cells (HSC) transdifferentiate into myofibroblasts, promoting extracellular matrix (ECM) synthesis and deposition…”
Get full text

Kinetics of miR-122 expression in the liver during acute HCV infection by Choi, Youkyung, Dienes, Hans-Peter, Krawczynski, Kris

“…The relationships among micro RNA-122 (miR-122) expression in the liver, hepatitis C virus (HCV) replication and hepatic damage were analyzed in three…”
Get full text

Chimeric mouse model for the infection of hepatitis B and C viruses by Tesfaye, Abeba, Stift, Judith, Maric, Dragan, Cui, Qingwen, Dienes, Hans-Peter, Feinstone, Stephen M

“…While the chimpanzee remains the only animal that closely models human hepatitis C virus (HCV) infection, transgenic and immunodeficient mice in which human…”
Get full text

Histopathological diagnosis of non-alcoholic and alcoholic fatty liver disease by Tannapfel, Andrea, Denk, Helmut, Dienes, Hans-Peter, Langner, Cord, Schirmacher, Peter, Trauner, Michael, Flott-Rahmel, Berenike

“…The diagnostic procedures in patients with suspected fatty liver disease—with or without known alcohol consumption—should be standardized and generally…”
Get full text

Combined analysis of HPV‐DNA, p16 and EGFR expression to predict prognosis in oropharyngeal cancer by Reimers, Niklas, Kasper, Hans U., Weissenborn, Soenke J., Stützer, Hartmut, Preuss, Simon F., Hoffmann, Thomas K., Speel, Ernst Jan M., Dienes, Hans P., Pfister, Herbert J., Guntinas‐Lichius, Orlando, Klussmann, Jens P.

“…Molecular prognostic indicators for oropharyngeal squamous cell carcinoma (OSCC), including HPV‐DNA detection, epidermal growth factor receptor (EGFR) and p16…”
Get full text

Long‐term follow‐up of antimitochondrial antibody–positive autoimmune hepatitis by O'Brien, Conor, Joshi, Supriya, Feld, Jordan J., Guindi, Maha, Dienes, Hans P., Heathcote, E. Jenny

“…Antimitochondrial antibodies (AMAs) are the serological hallmark for primary biliary cirrhosis (PBC). When AMAs are detected in patients with chronic…”
Get full text

Steatohepatitic hepatocellular Carcinoma:A new approach to classifying morphological subtypes of hepatocellular carcinoma by Soon, Gwyneth S.T., Callea, Francesco, Burt, Alastair D., Cook, Sam, Terracciano, Luigi, Ercan, Caner, Dienes, Hans-Peter, Goodman, Zachary D., Roberts, Eve A., Clouston, Andrew D., Gouw, Annette S.H., Kleiner, David E., Park, Young Nyun, Chung, Taek, Schirmacher, Peter, Tiniakos, Dina, Dimopoulou, Konstantina, Weber, Achim, Endhardt, Katharina, Torbenson, Michael

“…Histological subtyping of hepatocellular carcinoma (HCC) is challenging in the presence of histological heterogeneity, where distinctly different morphological…”
Get full text