Search Results - "Diembeck, W"

The Cosmetics Europe strategy for animal-free genotoxicity testing: Project status up-date by Pfuhler, S., Fautz, R., Ouedraogo, G., Latil, A., Kenny, J., Moore, C., Diembeck, W., Hewitt, N.J., Reisinger, K., Barroso, J.

“…•Overview of the Cosmetics Europe Genotoxicity Task projects.•Improved specificity by selecting relevant cells and sensitive toxicity measures.•Develop and…”
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Coenzyme Q10, a cutaneous antioxidant and energizer by Hoppe, U., Bergemann, J., Diembeck, W., Ennen, J., Gohla, S., Harris, I., Jacob, J., Kielholz, J., Mei, W., Pollet, D., Schachtschabel, D., Sauermann, G., Schreiner, V., Stäb, F., Steckel, F.

“…The processes of aging and photoaging are associated with an increase in cellular oxidation. This may be in part due to a decline in the levels of the…”
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Report from the EPAA workshop: In vitro ADME in safety testing used by EPAA industry sectors by Schroeder, K., Bremm, K.D., Alépée, N., Bessems, J.G.M., Blaauboer, B., Boehn, S.N., Burek, C., Coecke, S., Gombau, L., Hewitt, N.J., Heylings, J., Huwyler, J., Jaeger, M., Jagelavicius, M., Jarrett, N., Ketelslegers, H., Kocina, I., Koester, J., Kreysa, J., Note, R., Poth, A., Radtke, M., Rogiers, V., Scheel, J., Schulz, T., Steinkellner, H., Toeroek, M., Whelan, M., Winkler, P., Diembeck, W.

“…There are now numerous in vitro and in silico ADME alternatives to in vivo assays but how do different industries incorporate them into their decision tree…”
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Test Guidelines for In Vitro Assessment of Dermal Absorption and Percutaneous Penetration of Cosmetic Ingredients by Diembeck, W, Beck, H, Benech-Kieffer, F, Courtellemont, P, Dupuis, J, Lovell, W, Paye, M, Spengler, J, Steiling, W

“…The following guidelines present an in vitro alternative, which uses excised animal or human skin, to experiments conducted in vivo on animals or humans for…”
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Test guidelines for assessment of skin compatibility of cosmetic finished products in man by Walker, A.P., Basketter, D.A., Baverel, M., Diembeck, W., Matthies, W., Mougin, D., Paye, M., Röthlisberger, R., Dupuis, J.

“…The following guidelines present an alternative, by using humans, to the patch test on rabbits for assessment of the skin irritation potential of…”
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A toxicological review of topical exposure to white mineral oils by Nash, J.F., Gettings, S.D., Diembeck, W., Chudowski, M., Kraus, A.L.

“…White mineral oils have a long history of safe use by humans in orally ingested and topically applied products. A re-evaluation of the use of certain mineral…”
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Simultaneous HPLC determination of metabolites of the inflammatory cascade by Schepky, A G, Siegner, R, Diembeck, W

“…A model approach is presented to the in vivo inflammation cascade, in which the activities of key enzymes (phospholipase A2 [3.1.1.4], prostaglandin synthase…”
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Test guidelines for the assessment of skin tolerance of potentially irritant cosmetic ingredients in man by Walker, A.P., Basketter, D.A., Baverel, M., Diembeck, W., Matthies, W., Mougin, D., RÖthlisberger, R., Coroama, M.

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Use of Reconstructed Human Epidermis for Skin Absorption Testing: Results of the Validation Study by Schäfer-Korting, Monika, Bock, Udo, Diembeck, Walter, Düsing, Hans-Jürgen, Gamer, Armin, Haltner-Ukomadu, Eleonore, Hoffmann, Christine, Kaca, Monika, Kamp, Hennicke, Kersen, Silke, Kietzmann, Manfred, Korting, Hans Christian, Krächter, Hans-Udo, Lehr, Claus-Michael, Liebsch, Manfred, Mehling, Annette

“…A formal validation study was performed, in order to investigate whether the commerciallyavailable reconstructed human epidermis (RHE) models, EPISKIN, EpiDerm…”
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The Outermost Stratum Corneum Layer is an Effective Barrier Against Dermal Uptake of Topically Applied Micronized Titanium Dioxide by Pflücker, F., Hohenberg, H., Hölzle, E., Will, T., Pfeiffer, S., Wepf, R., Diembeck, W., Wenck, H., Gers-Barlag, H.

“…In order to help clarify the controversially discussed dermal uptake properties of micronized titanium dioxide (TiO ), we conducted extensive in vitro dermal…”
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Skin sensitisation and epidermal disposition: the relevance of epidermal disposition for sensitisation hazard identification and risk assessment. The report and recommendations of ECVAM workshop 59 by Basketter, David, Pease, Camilla, Kasting, Gerald, Kimber, Ian, Casati, Silvia, Cronin, Mark, Diembeck, Walter, Gerberick, Frank, Hadgraft, Jonathan, Hartung, Thomas, Marty, Jean-Paul, Nikolaidis, Efstathios, Patlewicz, Grace, Roberts, David, Roggen, Erwin, Rovida, Costanza, van de Sandt, Johannes

“…This is the 59th report of a series of workshops organised by the European Centre for the Validation of Alternative Methods (ECVAM). A workshop on Skin…”
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Barrier Characteristics of Different Human Skin Types Investigated with X-Ray Diffraction, Lipid Analysis, and Electron Microscopy Imaging by Schreiner, Volker, Pfeiffer, Stephan, Lanzendörfer, Ghita, Wenck, Horst, Diembeck, Walter, Gooris, Gert S., Proksch, Ehrhardt, Bouwstra, Joke

“…The stratum corneum requires ceramides, cholesterol, and fatty acids to provide the cutaneous permeability barrier. The lipids are organized in intercellular…”
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Development of an in vitro sensitization assay based on monocyte-derived dendritic cells by Schepky, Andreas, Spieker, Jochem, Gerlach, Silke, Kolbe, Ludger, Diembeck, Walter, Pape, Wolfgang, Wenck, Horst, Wittern, Klaus-Peter, Reuter, Hendrik

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The COLIPA strategy for animal-free genotoxicity testing by Diembeck, Walter, Carmichael, Paul, Aardema, Marilyn, Fautz, Rolf, Harvey, James, Hewitt, Nicky, Latil, Alain, Marrec-Fairley, Monique, Pfuhler, Stefan, Quedraogo, Gladys, Reisinger, Kerstin

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The COLIPA strategy for developing and evaluating animal alternatives for skin sensitization testing by Aeby, Pierre, Ashikaga, Takao, Bessou-Touya, Sandrine, Diembeck, Walter, Gerberick, Frank, Kern, Petra, Marrec-Fairley, Monique, Maxwell, Gavin, Ovigne, Jean-Marc, Sakaguchi, Hitoshi, Schroeder, Klaus, Tailhardat, Magali, Teissier, Silvia, Winkler, Petra

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Test guidelines for in vitro assessment of dermal absorption and percutaneous penetration of cosmetic ingredients. European Cosmetic, Toiletry and Perfumery Association by Diembeck, W, Beck, H, Benech-Kieffer, F, Courtellemont, P, Dupuis, J, Lovell, W, Paye, M, Spengler, J, Steiling, W

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Test guidelines for the assessment of skin tolerance of potentially irritant cosmetic ingredients in man by Walker, A P, Basketter, DA, Baverel, M, Diembeck, W, Matthies, W, Mougin, D, Roethlisberger, R, Coroama, M

“…The following guidelines complement the previous publication by presenting guidelines for the assessment of the tolerance of human skin to the chemical…”
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Test guidelines for the assessment of skin tolerance of potentially irritant cosmetic ingredients in man. European Cosmetic, Toiletry and Perfumery Association by Walker, A P, Basketter, D A, Baverel, M, Diembeck, W, Matthies, W, Mougin, D, Röthlisberger, R, Coroama, M

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Test guidelines for assessment of skin compatibility of cosmetic finished products in man. Task Force of COLIPA by Walker, A P, Basketter, D A, Baverel, M, Diembeck, W, Matthies, W, Mougin, D, Paye, M, Röthlisberger, R, Dupuis, J

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Clinical and biophysical efficacy of a novel coenzyme Q10 containing anti-wrinkle cream (Eucerin® Q10 active) by Schölermann, A., Wendt, G., Diembeck, W., Ennen, J., Gohla, S., Kielholz, J., Nielsen, J., Sauermann, G., Stäb, F., Schreiner, V., Hoppe, U., Rippke, F., Moll, I.

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