Search Results - "Diem, Alexandra K"

A control mechanism for intra-mural peri-arterial drainage via astrocytes: How neuronal activity could improve waste clearance from the brain by Diem, Alexandra K, Carare, Roxana O, Weller, Roy O, Bressloff, Neil W

“…The mechanisms behind the clearance of soluble waste from deep within the parenchyma of the brain remain unclear. Experimental evidence reveals that one…”
Get full text

Arterial Pulsations cannot Drive Intramural Periarterial Drainage: Significance for A β Drainage by Diem, Alexandra K, MacGregor Sharp, Matthew, Gatherer, Maureen, Bressloff, Neil W, Carare, Roxana O, Richardson, Giles

“…Alzheimer's Disease (AD) is the most common form of dementia and to date there is no cure or efficient prophylaxis. The cognitive decline correlates with the…”
Get full text

VaMpy: A Python Package to Solve 1D Blood Flow Problems by Diem, Alexandra K, Bressloff, Neil W

“…Finite-differences methods such as the Lax-Wendroff method (LW) are commonly used to solve 1D models of blood flow. These models solve for blood flow and lumen…”
Get full text

Time-Lapsing Perfusion: Proof of Concept of a Novel Method to Study Drug Delivery in Whole Organs by Diem, Alexandra K., Valen-Sendstad, Kristian

“…Perfusion is one of the most important processes maintaining organ health. From a computational perspective, however, perfusion is among the least-studied…”
Get full text

Peristalsis with Oscillating Flow Resistance: A Mechanism for Periarterial Clearance of Amyloid Beta from the Brain by Sharp, M. Keith, Diem, Alexandra K., Weller, Roy O., Carare, Roxana O.

“…Alzheimer’s disease is characterized by accumulation of amyloid- β (A β ) in the brain and in the walls of cerebral arteries. The focus of this work is on…”
Get full text

Sustainable computational science: the ReScience initiative by Rougier, Nicolas P, Hinsen, Konrad, Alexandre, Frédéric, Arildsen, Thomas, Barba, Lorena A, Benureau, Fabien C.Y, Brown, C. Titus, de Buyl, Pierre, Caglayan, Ozan, Davison, Andrew P, Delsuc, Marc-André, Detorakis, Georgios, Diem, Alexandra K, Drix, Damien, Enel, Pierre, Girard, Benoît, Guest, Olivia, Hall, Matt G, Henriques, Rafael N, Hinaut, Xavier, Jaron, Kamil S, Khamassi, Mehdi, Klein, Almar, Manninen, Tiina, Marchesi, Pietro, McGlinn, Daniel, Metzner, Christoph, Petchey, Owen, Plesser, Hans Ekkehard, Poisot, Timothée, Ram, Karthik, Ram, Yoav, Roesch, Etienne, Rossant, Cyrille, Rostami, Vahid, Shifman, Aaron, Stachelek, Joseph, Stimberg, Marcel, Stollmeier, Frank, Vaggi, Federico, Viejo, Guillaume, Vitay, Julien, Vostinar, Anya E, Yurchak, Roman, Zito, Tiziano

“…Computer science offers a large set of tools for prototyping, writing, running, testing, validating, sharing and reproducing results; however, computational…”
Get full text

A Simulation Model of Periarterial Clearance of Amyloid-β from the Brain by Diem, Alexandra K, Tan, Mingyi, Bressloff, Neil W, Hawkes, Cheryl, Morris, Alan W J, Weller, Roy O, Carare, Roxana O

“…The accumulation of soluble and insoluble amyloid-β (Aβ) in the brain indicates failure of elimination of Aβ from the brain with age and Alzheimer's disease…”
Get full text

Porous Modelling of Cardiac Perfusion under Contraction to Demonstrate the Distribution of Therapeutic Nanoparticles by Diem, Alexandra K, Valen-Sendstad, Kristian

“…Delivery of therapy-loaded nanoparticles (NP) via inhalation is an innovative technology shown to successfully reduce heart failure in mice, improving the…”
Get full text

A control mechanism for intramural periarterial drainage via astrocytes: How neuronal activity could improve waste clearance from the brain by Diem, Alexandra K, Carare, Roxana O, Bressloff, Neil. W

“…The mechanisms behind waste clearance from deep within the parenchyma of the brain remain unclear to this date. Experimental evidence has shown that one…”
Get full text

Sustainable computational science: the ReScience initiative by Rougier, Nicolas P, Hinsen, Konrad, Alexandre, Frédéric, Arildsen, Thomas, Barba, Lorena, Benureau, Fabien C. Y, Brown, C. Titus, de Buyl, Pierre, Caglayan, Ozan, Davison, Andrew P, Delsuc, Marc André, Detorakis, Georgios, Diem, Alexandra K, Drix, Damien, Enel, Pierre, Girard, Benoît, Guest, Olivia, Hall, Matt G, Henriques, Rafael Neto, Hinaut, Xavier, Jaron, Kamil S, Khamassi, Mehdi, Klein, Almar, Manninen, Tiina, Marchesi, Pietro, McGlinn, Dan, Metzner, Christoph, Petchey, Owen L, Plesser, Hans Ekkehard, Poisot, Timothée, Ram, Karthik, Ram, Yoav, Roesch, Etienne, Rossant, Cyrille, Rostami, Vahid, Shifman, Aaron, Stachelek, Joseph, Stimberg, Marcel, Stollmeier, Frank, Vaggi, Federico, Viejo, Guillaume, Vitay, Julien, Vostinar, Anya, Yurchak, Roman, Zito, Tiziano

“…PeerJ Computer Science 3:e142 (2017) Computer science offers a large set of tools for prototyping, writing, running, testing, validating, sharing and…”
Get full text