Search Results - "Diehl, Diane M."
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Systematic and comprehensive strategy for reducing matrix effects in LC/MS/MS analyses
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-06-2007)“…A systematic, comprehensive strategy that optimizes sample preparation and chromatography to minimize matrix effects in bioanalytical LC/MS/MS assays was…”
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Journal Article -
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Systematic development of an UPLC–MS/MS method for the determination of tricyclic antidepressants in human urine
Published in Journal of pharmaceutical and biomedical analysis (01-01-2014)“…•The UPLC–MS/MS method measures five tricyclic antidepressants in human urine.•Simple screening protocols and subsequent optimization delivered the final…”
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Journal Article -
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Simultaneous analysis of morphine-related compounds in plasma using mixed-mode solid phase extraction and UltraPerformance liquid chromatography-mass spectrometry
Published in Journal of separation science (01-07-2009)“…A bioanalytical method using mixed-mode solid phase extraction and UltraPerformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was developed…”
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Journal Article -
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Effects of extra-column band spreading, liquid chromatography system operating pressure, and column temperature on the performance of sub-2-μm porous particles
Published in Journal of Chromatography A (07-08-2009)“…The effects of extra-column band spreading, LC system operating pressure, and separation temperature were investigated for sub-2-μm particle columns using both…”
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Journal Article -
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Influence of stationary phase chemistry and mobile-phase composition on retention, selectivity, and MS response in hydrophilic interaction chromatography
Published in Journal of separation science (01-03-2010)“…A comprehensive retention and selectivity characterization of several hydrophilic interaction chromatography (HILIC) stationary phases was performed with 28…”
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Journal Article -
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application of novel 1.7 μm ethylene bridged hybrid particles for hydrophilic interaction chromatography
Published in Journal of separation science (01-05-2008)“…An un-derivatized 1.7 μm ethylene bridged hybrid (BEH) particle was evaluated for its utility in retaining polar species in hydrophilic interaction…”
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Journal Article -
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Differences in preparative loadability between the charged and uncharged forms of ionizable compounds
Published in Journal of Chromatography A (19-03-2004)“…Ionizable compounds experience a drastic difference in preparative loadability as a function of pH. It can be shown that the preparative loadability of a…”
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Journal Article Conference Proceeding -
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The application of novel 1.7 mum ethylene bridged hybrid particles for hydrophilic interaction chromatography
Published in Journal of separation science (01-05-2008)“…An un-derivatized 1.7 m ethylene bridged hybrid (BEH) particle was evaluated for its utility in retaining polar species in hydrophilic interaction…”
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The application of novel 1.7 microm ethylene bridged hybrid particles for hydrophilic interaction chromatography
Published in Journal of separation science (01-05-2008)“…An un-derivatized 1.7 microm ethylene bridged hybrid (BEH) particle was evaluated for its utility in retaining polar species in hydrophilic interaction…”
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Journal Article -
11
Effects of extra-column band spreading, liquid chromatography system operating pressure, and column temperature on the performance of sub-2-microm porous particles
Published in Journal of chromatography. A (07-08-2009)“…The effects of extra-column band spreading, LC system operating pressure, and separation temperature were investigated for sub-2-microm particle columns using…”
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Journal Article -
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SIMPLIFYING PEPTIDE BIOANALYSIS
Published in Pharmaceutical Technology (01-11-2009)Get full text
Trade Publication Article -
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N-linked glycans of glycoproteins: a new column for improved resolution
Published in Biopharm International (01-11-2009)“…Since the labeled oligosaccharides are very hydrophilic, the preferred mode of separation is Hydrophilic Interaction Chromatography (HIUC). Since the set of…”
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Magazine Article Trade Publication Article -
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Monitoring cell culture media with the UPLC amino acid analysis solution
Published in Biopharm International (01-11-2009)“…AccQ*Tag Ultra Cell Culture Method Injection volume: 1 µL RESULTS An analysis of amino acid standards representing the compounds commonly found in cell culture…”
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Magazine Article Trade Publication Article