Search Results - "Diehl, Anna M"

Cause, Pathogenesis, and Treatment of Nonalcoholic Steatohepatitis by Diehl, Anna M, Day, Christopher

“…Nonalcoholic steatohepatitis is a major cause of cirrhosis and liver cancer. It is associated with visceral adiposity and the metabolic syndrome and is nearly…”
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Thyroid hormone receptor alpha modulates fibrogenesis in hepatic stellate cells by Manka, Paul, Coombes, Jason D., Sydor, Svenja, Swiderska‐Syn, Marzena K., Best, Jan, Gauthier, Karine, Grunsven, Leo A., Oo, Ye H., Wang, Cindy, Diehl, Anna M., Hönes, Georg S., Moeller, Lars C., Figge, Anja, Boosman, René J., Faber, Klaas N., Tannapfel, Andrea, Goetze, Oliver, Aspichueta, Patricia, Lange, Christian M., Canbay, Ali, Syn, Wing‐Kin

“…Objective Progressive hepatic fibrosis can be considered the final stage of chronic liver disease. Hepatic stellate cells (HSC) play a central role in liver…”
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Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma by Pereira, Thiago de Almeida, Witek, Rafal P, Syn, Wing-Kin, Choi, Steve S, Bradrick, Shelton, Karaca, Gamze F, Agboola, Kolade M, Jung, Youngmi, Omenetti, Alessia, Moylan, Cynthia A, Yang, Liu, Fernandez-Zapico, Martin E, Jhaveri, Ravi, Shah, Vijay H, Pereira, Fausto E, Diehl, Anna M

“…Hedgehog (Hh) pathway activation promotes many processes that occur during fibrogenic liver repair. Whether the Hh pathway modulates the outcomes of virally…”
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MicroRNA-375 Suppresses the Growth and Invasion of Fibrolamellar Carcinoma by Dinh, Timothy A, Jewell, Mark L, Kanke, Matt, Francisco, Adam, Sritharan, Ramja, Turnham, Rigney E, Lee, Seona, Kastenhuber, Edward R, Wauthier, Eliane, Guy, Cynthia D, Yeung, Raymond S, Lowe, Scott W, Reid, Lola M, Scott, John D, Diehl, Anna M, Sethupathy, Praveen

“…Background & Aims Fibrolamellar carcinoma (FLC) is a rare liver cancer that primarily affects adolescents and young adults. It is characterized by a…”
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Overexpression of caspase-3 in hepatocellular carcinomas by Persad, Rajendra, Liu, Chen, Wu, Tsung-Teh, Houlihan, Patrick S, Hamilton, Stanley R, Diehl, Anna M, Rashid, Asif

“…Caspase-3 is a downstream effector cysteine protease in the apoptotic pathway. It is ubiquitously expressed in normal human tissues including the liver…”
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Implication of gut microbiota in nonalcoholic fatty liver disease by Boursier, Jerome, Diehl, Anna Mae

“…It is now well established that gut flora and chronic liver diseases are closely interrelated. This association is most evident at late stages of the disease:…”
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Nonalcoholic Steatohepatitis by Yildiz, Halil, Ashrafian, Hutan, Sachak, Taha, Yearsley, Martha, Levin, Douglas, Rahmoune, Hakim, Boutrid, Nada, Bioud, Belkacem, Diehl, Anna M, Day, Christopher

“…To the Editor: In the review article by Diehl and Day (Nov. 23 issue), 1 about the cause, pathogenesis, and treatment of nonalcoholic steatohepatitis, the…”
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Nonalcoholic steatosis and steatohepatitis IV. Nonalcoholic fatty liver disease abnormalities in macrophage function and cytokines by Diehl, Anna Mae

“…Macrophage products, such as cytokines, prostanoids, nitric oxide, and reactive oxygen intermediates, influence the function and viability of macrophages and…”
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Differential effects of arsenic trioxide on chemosensitization in human hepatic tumor and stellate cell lines by Rangwala, Fatima, Williams, Kevin P, Smith, Ginger R, Thomas, Zainab, Allensworth, Jennifer L, Lyerly, H Kim, Diehl, Anna Mae, Morse, Michael A, Devi, Gayathri R

“…Crosstalk between malignant hepatocytes and the surrounding peritumoral stroma is a key modulator of hepatocarcinogenesis and therapeutic resistance. To…”
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MicroRNA-375 Suppresses the Growth and Invasion of Fibrolamellar CarcinomaSummary by Timothy A. Dinh, Mark L. Jewell, Matt Kanke, Adam Francisco, Ramja Sritharan, Rigney E. Turnham, Seona Lee, Edward R. Kastenhuber, Eliane Wauthier, Cynthia D. Guy, Raymond S. Yeung, Scott W. Lowe, Lola M. Reid, John D. Scott, Anna M. Diehl, Praveen Sethupathy

“…Background & Aims: Fibrolamellar carcinoma (FLC) is a rare liver cancer that primarily affects adolescents and young adults. It is characterized by a…”
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Kupffer cell depletion by CI2MDP-liposomes alters hepatic cytokine expression and delays liver regeneration after partial hepatectomy by Meijer, Catharina, Wiezer, Marinus J., Diehl, Anna M., Yang, Shi-Qi, Schouten, Hylke J., Meijer, Sybren, Van Rooijen, Nico, Van Lambalgen, Antonie A., Dijkstra, Christine D., Van Leeuwen, Paul A. M.

“…: Background: Although Kupffer cells (KCs) are capable of producing important growth‐stimulating cytokines, their role in liver regeneration following partial…”
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The Diagnosis and Management of Non-alcoholic Fatty Liver Disease: Practice Guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology by Chalasani, Naga, MD, FACG, Younossi, Zobair, MD, FACG, Lavine, Joel E., MD, PhD, Diehl, Anna Mae, MD, Brunt, Elizabeth M., MD, Cusi, Kenneth, MD, Charlton, Michael, MD, Sanyal, Arun J., MD

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Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma: Hepatitis Infection and hedgehog signaling p66Shc impairs liver regeneration in aged mice Mouse model of autoimmune pancreatitis by DE ALMEIDA PEREIRA, Thiago, WITEK, Rafal P, LIU YANG, FERNANDEZ-ZAPICO, Martin E, JHAVERI, Ravi, SHAH, Vijay H, PEREIRA, Fausto E, DIEHL, Anna M, SYN, Wing-Kin, CHOI, Steve S, BRADRICK, Shelton, KARACA, Gamze F, AGBOOLA, Kolade M, YOUNGMI JUNG, OMENETTI, Alessia, MOYLAN, Cynthia A

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Nonalcoholic Fatty Liver Disease and the Gut Microbiome by Boursier, Jerome, MD, PhD, Diehl, Anna Mae, MD

“…Recent progress has allowed a more comprehensive study of the gut microbiota. Gut microbiota helps in health maintenance and gut dysbiosis associates with…”
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Hepatic Complications of Obesity by Diehl, Anna Mae, MD

“…Obesity is associated with a spectrum of chronic liver disease. Because obesity increases the risk for advanced forms of liver disease (ie, cirrhosis and liver…”
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Nonalcoholic Fatty Liver Disease as a Complication of Insulin Resistance by Abdelmalek, Manal F., MD, MPH, Diehl, Anna Mae, MD

“…Nonalcoholic fatty liver disease (NAFLD) refers to a spectrum of liver damage ranging from simple steatosis to nonalcoholic steatohepatitis, advanced fibrosis,…”
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Inflammation Writes the Fibrogenic Code by Friedersdorf, Matthew, Diehl, Anna Mae

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Apoptosis and Cytokines in Non-Alcoholic Steatohepatitis by Syn, Wing-Kin, MBChB, MRCP, Choi, Steve S., MD, Diehl, Anna Mae, MD

“…Non-alcoholic fatty liver disease (NAFLD), one of the commonest causes of chronic liver disease in the United States, represents several overlapping…”
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Liver Renewal: Detecting Misrepair and Optimizing Regeneration by Machado, Mariana Verdelho, MD, Diehl, Anna Mae, MD

“…Abstract Cirrhosis and liver cancer, the main causes of liver-related morbidity and mortality, result from defective repair of liver injury. This article…”
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Costaining for keratins 8/18 plus ubiquitin improves detection of hepatocyte injury in nonalcoholic fatty liver disease by Guy, Cynthia D., MD, Suzuki, Ayako, MD, PhD, Burchette, James L., HT, Brunt, Elizabeth M., MD, Abdelmalek, Manal F., MD, MPH, Cardona, Diana, MD, McCall, Shannon J., MD, Ünalp, Aynur, MD, PhD, Belt, Patricia, BS, Ferrell, Linda D., MD, Diehl, Anna Mae, MD

“…Summary Nonalcoholic fatty liver disease is a global health dilemma. The gold standard for diagnosis is liver biopsy. Ballooned hepatocytes are histologic…”
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